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The landscape of tolerated genetic variation in humans and primates.

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Title: The landscape of tolerated genetic variation in humans and primates.
Authors: Gao H; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Hamp T; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Ede J; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Schraiber JG; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., McRae J; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Singer-Berk M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA., Yang Y; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Dietrich A; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Fiziev P; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Kuderna L; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain., Sundaram L; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Wu Y; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Adhikari A; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Field Y; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Chen C; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Batzoglou S; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Aguet F; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA., Lemire G; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA.; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA., Reimers R; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA., Balick D; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA., Janiak MC; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom., Kuhlwilm M; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Department of Evolutionary Anthropology, University of Vienna; Djerassiplatz 1, 1030, Vienna, Austria.; Human Evolution and Archaeological Sciences (HEAS), University of Vienna; 1030, Vienna, Austria., Orkin JD; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Département d'anthropologie, Université de Montréal; 3150 Jean-Brillant, Montréal, QC, H3T 1N8, Canada., Manu S; Academy of Scientific and Innovative Research (AcSIR); Ghaziabad, 201002, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology; Hyderabad, 500007, India., Valenzuela A; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain., Bergman J; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark.; Section for Ecoinformatics & Biodiversity, Department of Biology, Aarhus University; Aarhus, 8000, Denmark., Rouselle M; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark., Silva FE; Research Group on Primate Biology and Conservation, Mamirauá Institute for Sustainable Development; Estrada da Bexiga 2584, Tefé, Amazonas, CEP 69553-225, Brazil.; Faculty of Sciences, Department of Organismal Biology, Unit of Evolutionary Biology and Ecology, Université Libre de Bruxelles (ULB); Avenue Franklin D. Roosevelt 50, 1050, Brussels, Belgium., Agueda L; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain., Blanc J; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain., Gut M; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain., de Vries D; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom., Goodhead I; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom., Harris RA; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine; Houston, Texas, 77030, USA., Raveendran M; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine; Houston, Texas, 77030, USA., Jensen A; Department of Ecology and Genetics, Animal Ecology, Uppsala University; SE-75236, Uppsala, Sweden., Chuma IS; Tanzania National Parks; Arusha, Tanzania., Horvath J; North Carolina Museum of Natural Sciences; Raleigh, North Carolina, 27601, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University; Durham, North Carolina , 27707, USA.; Department of Biological Sciences, North Carolina State University; Raleigh, North Carolina , 27695, USA.; Department of Evolutionary Anthropology, Duke University; Durham, North Carolina , 27708, USA.; Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Hvilsom C; Copenhagen Zoo; 2000 Frederiksberg, Denmark., Juan D; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain., Frandsen P; Copenhagen Zoo; 2000 Frederiksberg, Denmark., de Melo FR; Universidade Federal de Viçosa; Viçosa, 36570-900, Brazil., Bertuol F; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL); Manaus, Amazonas, 69080-900, Brazil., Byrne H; Department of Anthropology, University of Utah; Salt Lake City, Utah, 84102, USA., Sampaio I; Universidade Federal do Para; Guamá, Belém - PA, 66075-110, Brazil., Farias I; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL); Manaus, Amazonas, 69080-900, Brazil., do Amaral JV; Research Group on Terrestrial Vertebrate Ecology, Mamirauá Institute for Sustainable Development; Tefé, Amazonas, 69553-225, Brazil.; Rede de Pesquisa para Estudos sobre Diversidade, Conservação e Uso da Fauna na Amazônia - RedeFauna; Manaus, Amazonas, 69080-900, Brazil.; Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica - ComFauna; Iquitos, Loreto, 16001, Peru., Messias M; Universidade Federal de Rondonia; Porto Velho, Rondônia, 78900-000, Brazil.; PPGREN - Programa de Pós-Graduação 'Conservação e Uso dos Recursos Naturais and BIONORTE - Programa de Pós-Graduação em Biodiversidade e Biotecnologia da Rede BIONORTE, Universidade Federal de Rondonia; Porto Velho, Rondônia, 78900-000, Brazil., da Silva MNF; Instituto Nacional de Pesquisas da Amazonia; Petrópolis, Manaus - AM, 69067-375, Brazil., Trivedi M; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology; Hyderabad, 500007, India., Rossi R; Universidade Federal do Mato Grosso; Boa Esperança, Cuiabá - MT, 78060-900, Brazil., Hrbek T; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL); Manaus, Amazonas, 69080-900, Brazil.; Department of Biology, Trinity University; San Antonio, Texas, 78212, USA., Andriaholinirina N; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga; Mahajanga, 401, Madagascar., Rabarivola CJ; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga; Mahajanga, 401, Madagascar., Zaramody A; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga; Mahajanga, 401, Madagascar., Jolly CJ; New York University; New York City, 10012, USA., Phillips-Conroy J; Washington University in St. Louis; St. Louis, Missouri,63130, USA., Wilkerson G; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center; Houston, Texas, 77030, USA., Abee C; Yale University; New Haven, Connecticut, 06520, USA., Simmons JH; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center; Houston, Texas, 77030, USA., Fernandez-Duque E; Yale University; New Haven, Connecticut, 06520, USA.; Universidad Nacional de Formosa, Argentina Fundacion ECO, Formosa, Argentina., Kanthaswamy S; Arizona State University; Tempe, Arizona, 85281, USA., Shiferaw F; Hawassa University; Hawassa, 005, Ethiopia., Wu D; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences; Kunming, Yunnan, 650223, China., Zhou L; Center for Evolutionary & Organismal Biology, Zhejiang University School of Medicine, Hangzhou, 310058, China., Shao Y; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences; Kunming, Yunnan, 650223, China., Zhang G; Center for Evolutionary & Organismal Biology, Zhejiang University School of Medicine, Hangzhou, 310058, China.; Villum Center for Biodiversity Genomics, Section for Ecology and Evolution, Department of Biology, University of Copenhagen; Copenhagen, DK-2100, Denmark.; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China.; Liangzhu Laboratory, Zhejiang University Medical Center; 1369 West Wenyi Road, Hangzhou, 311121, China.; Women's Hospital, School of Medicine, Zhejiang University; 1 Xueshi Road, Shangcheng District, Hangzhou, 310006, China., Keyyu JD; Tanzania Wildlife Research Institute (TAWIRI), Head Office; P.O.Box 661, Arusha, Tanzania., Knauf S; Institute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health; 17493 Greifswald - Isle of Riems, Germany., Le MD; Department of Environmental Ecology, Faculty of Environmental Sciences, University of Science and Central Institute for Natural Resources and Environmental Studies, Vietnam National University; Hanoi, 100000, Vietnam., Lizano E; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain., Merker S; Department of Zoology, State Museum of Natural History Stuttgart; 70191 Stuttgart, Germany., Navarro A; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA) and Universitat Pompeu Fabra, Pg. Luís Companys 23, Barcelona, 08010, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology; Av. Doctor Aiguader, N88, Barcelona, 08003, Spain.; BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation; C. Wellington 30, Barcelona, 08005, Spain., Batallion T; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark., Nadler T; Cuc Phuong Commune; Nho Quan District, Ninh Binh Province, 430000, Vietnam., Khor CC; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Republic of Singapore., Lee J; Mandai Nature; 80 Mandai Lake Road, Singapore 729826, Republic of Singapore., Tan P; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Republic of Singapore.; SingHealth Duke-NUS Institute of Precision Medicine (PRISM); Singapore 168582, Republic of Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School; Singapore 168582, Republic of Singapore., Lim WK; SingHealth Duke-NUS Institute of Precision Medicine (PRISM); Singapore 168582, Republic of Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School; Singapore 168582, Republic of Singapore.; SingHealth Duke-NUS Genomic Medicine Centre; Singapore 168582, Republic of Singapore., Kitchener AC; Department of Natural Sciences, National Museums Scotland; Chambers Street, Edinburgh, EH1 1JF, UK.; School of Geosciences, University of Edinburgh; Drummond Street, Edinburgh, EH8 9XP, UK., Zinner D; Cognitive Ethology Laboratory, Germany Primate Center, Leibniz Institute for Primate Research; 37077 Göttingen, Germany.; Department of Primate Cognition, Georg-August-Universität Göttingen; 37077 Göttingen, Germany., Gut I; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain.; Universitat Pompeu Fabra, Pg. Luís Companys 23, Barcelona, 08010, Spain., Melin A; Leibniz Science Campus Primate Cognition; 37077 Göttingen, Germany.; Department of Anthropology & Archaeology and Department of Medical Genetics., Guschanski K; Department of Ecology and Genetics, Animal Ecology, Uppsala University; SE-75236, Uppsala, Sweden.; Alberta Children's Hospital Research Institute; University of Calgary; 2500 University Dr NW T2N 1N4, Calgary, Alberta, Canada., Schierup MH; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark., Beck RMD; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom., Umapathy G; Academy of Scientific and Innovative Research (AcSIR); Ghaziabad, 201002, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology; Hyderabad, 500007, India., Roos C; Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh; Edinburgh, EH8 9XP, UK., Boubli JP; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom., Lek M; Gene Bank of Primates and Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research; Kellnerweg 4, 37077 Göttingen, Germany., Sunyaev S; Department of Genetics, Yale School of Medicine; New Haven, Connecticut, 06520, USA.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA., O'Donnell A; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA.; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, 02115, USA., Rehm H; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, 02115, USA., Xu J; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.; Toyota Technological Institute at Chicago; Chicago, Illinois, 60637, USA., Rogers J; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine; Houston, Texas, 77030, USA., Marques-Bonet T; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA) and Universitat Pompeu Fabra, Pg. Luís Companys 23, Barcelona, 08010, Spain., Kai-How Farh K; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 02. Date of Electronic Publication: 2023 May 02.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 37205491
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: The landscape of tolerated genetic variation in humans and primates.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Gao+H%22">Gao H</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Hamp+T%22">Hamp T</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Ede+J%22">Ede J</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Schraiber+JG%22">Schraiber JG</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22McRae+J%22">McRae J</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Singer-Berk+M%22">Singer-Berk M</searchLink>; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Dietrich+A%22">Dietrich A</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Fiziev+P%22">Fiziev P</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Kuderna+L%22">Kuderna L</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sundaram+L%22">Sundaram L</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Adhikari+A%22">Adhikari A</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Field+Y%22">Field Y</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Batzoglou+S%22">Batzoglou S</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Aguet+F%22">Aguet F</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.<br /><searchLink fieldCode="AU" term="%22Lemire+G%22">Lemire G</searchLink>; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA.; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Reimers+R%22">Reimers R</searchLink>; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Balick+D%22">Balick D</searchLink>; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Janiak+MC%22">Janiak MC</searchLink>; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kuhlwilm+M%22">Kuhlwilm M</searchLink>; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Department of Evolutionary Anthropology, University of Vienna; Djerassiplatz 1, 1030, Vienna, Austria.; Human Evolution and Archaeological Sciences (HEAS), University of Vienna; 1030, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Orkin+JD%22">Orkin JD</searchLink>; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Département d'anthropologie, Université de Montréal; 3150 Jean-Brillant, Montréal, QC, H3T 1N8, Canada.<br /><searchLink fieldCode="AU" term="%22Manu+S%22">Manu S</searchLink>; Academy of Scientific and Innovative Research (AcSIR); Ghaziabad, 201002, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology; Hyderabad, 500007, India.<br /><searchLink fieldCode="AU" term="%22Valenzuela+A%22">Valenzuela A</searchLink>; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bergman+J%22">Bergman J</searchLink>; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark.; Section for Ecoinformatics & Biodiversity, Department of Biology, Aarhus University; Aarhus, 8000, Denmark.<br /><searchLink fieldCode="AU" term="%22Rouselle+M%22">Rouselle M</searchLink>; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark.<br /><searchLink fieldCode="AU" term="%22Silva+FE%22">Silva FE</searchLink>; Research Group on Primate Biology and Conservation, Mamirauá Institute for Sustainable Development; Estrada da Bexiga 2584, Tefé, Amazonas, CEP 69553-225, Brazil.; Faculty of Sciences, Department of Organismal Biology, Unit of Evolutionary Biology and Ecology, Université Libre de Bruxelles (ULB); Avenue Franklin D. Roosevelt 50, 1050, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Agueda+L%22">Agueda L</searchLink>; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Blanc+J%22">Blanc J</searchLink>; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gut+M%22">Gut M</searchLink>; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22de+Vries+D%22">de Vries D</searchLink>; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goodhead+I%22">Goodhead I</searchLink>; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Harris+RA%22">Harris RA</searchLink>; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine; Houston, Texas, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Raveendran+M%22">Raveendran M</searchLink>; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine; Houston, Texas, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Jensen+A%22">Jensen A</searchLink>; Department of Ecology and Genetics, Animal Ecology, Uppsala University; SE-75236, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Chuma+IS%22">Chuma IS</searchLink>; Tanzania National Parks; Arusha, Tanzania.<br /><searchLink fieldCode="AU" term="%22Horvath+J%22">Horvath J</searchLink>; North Carolina Museum of Natural Sciences; Raleigh, North Carolina, 27601, USA.; Department of Biological and Biomedical Sciences, North Carolina Central University; Durham, North Carolina , 27707, USA.; Department of Biological Sciences, North Carolina State University; Raleigh, North Carolina , 27695, USA.; Department of Evolutionary Anthropology, Duke University; Durham, North Carolina , 27708, USA.; Renaissance Computing Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Hvilsom+C%22">Hvilsom C</searchLink>; Copenhagen Zoo; 2000 Frederiksberg, Denmark.<br /><searchLink fieldCode="AU" term="%22Juan+D%22">Juan D</searchLink>; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Frandsen+P%22">Frandsen P</searchLink>; Copenhagen Zoo; 2000 Frederiksberg, Denmark.<br /><searchLink fieldCode="AU" term="%22de+Melo+FR%22">de Melo FR</searchLink>; Universidade Federal de Viçosa; Viçosa, 36570-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Bertuol+F%22">Bertuol F</searchLink>; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL); Manaus, Amazonas, 69080-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Byrne+H%22">Byrne H</searchLink>; Department of Anthropology, University of Utah; Salt Lake City, Utah, 84102, USA.<br /><searchLink fieldCode="AU" term="%22Sampaio+I%22">Sampaio I</searchLink>; Universidade Federal do Para; Guamá, Belém - PA, 66075-110, Brazil.<br /><searchLink fieldCode="AU" term="%22Farias+I%22">Farias I</searchLink>; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL); Manaus, Amazonas, 69080-900, Brazil.<br /><searchLink fieldCode="AU" term="%22do+Amaral+JV%22">do Amaral JV</searchLink>; Research Group on Terrestrial Vertebrate Ecology, Mamirauá Institute for Sustainable Development; Tefé, Amazonas, 69553-225, Brazil.; Rede de Pesquisa para Estudos sobre Diversidade, Conservação e Uso da Fauna na Amazônia - RedeFauna; Manaus, Amazonas, 69080-900, Brazil.; Comunidad de Manejo de Fauna Silvestre en la Amazonía y en Latinoamérica - ComFauna; Iquitos, Loreto, 16001, Peru.<br /><searchLink fieldCode="AU" term="%22Messias+M%22">Messias M</searchLink>; Universidade Federal de Rondonia; Porto Velho, Rondônia, 78900-000, Brazil.; PPGREN - Programa de Pós-Graduação 'Conservação e Uso dos Recursos Naturais and BIONORTE - Programa de Pós-Graduação em Biodiversidade e Biotecnologia da Rede BIONORTE, Universidade Federal de Rondonia; Porto Velho, Rondônia, 78900-000, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+MNF%22">da Silva MNF</searchLink>; Instituto Nacional de Pesquisas da Amazonia; Petrópolis, Manaus - AM, 69067-375, Brazil.<br /><searchLink fieldCode="AU" term="%22Trivedi+M%22">Trivedi M</searchLink>; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology; Hyderabad, 500007, India.<br /><searchLink fieldCode="AU" term="%22Rossi+R%22">Rossi R</searchLink>; Universidade Federal do Mato Grosso; Boa Esperança, Cuiabá - MT, 78060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Hrbek+T%22">Hrbek T</searchLink>; Universidade Federal do Amazonas, Departamento de Genética, Laboratório de Evolução e Genética Animal (LEGAL); Manaus, Amazonas, 69080-900, Brazil.; Department of Biology, Trinity University; San Antonio, Texas, 78212, USA.<br /><searchLink fieldCode="AU" term="%22Andriaholinirina+N%22">Andriaholinirina N</searchLink>; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga; Mahajanga, 401, Madagascar.<br /><searchLink fieldCode="AU" term="%22Rabarivola+CJ%22">Rabarivola CJ</searchLink>; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga; Mahajanga, 401, Madagascar.<br /><searchLink fieldCode="AU" term="%22Zaramody+A%22">Zaramody A</searchLink>; Life Sciences and Environment, Technology and Environment of Mahajanga, University of Mahajanga; Mahajanga, 401, Madagascar.<br /><searchLink fieldCode="AU" term="%22Jolly+CJ%22">Jolly CJ</searchLink>; New York University; New York City, 10012, USA.<br /><searchLink fieldCode="AU" term="%22Phillips-Conroy+J%22">Phillips-Conroy J</searchLink>; Washington University in St. Louis; St. Louis, Missouri,63130, USA.<br /><searchLink fieldCode="AU" term="%22Wilkerson+G%22">Wilkerson G</searchLink>; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center; Houston, Texas, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Abee+C%22">Abee C</searchLink>; Yale University; New Haven, Connecticut, 06520, USA.<br /><searchLink fieldCode="AU" term="%22Simmons+JH%22">Simmons JH</searchLink>; Keeling Center for Comparative Medicine and Research, MD Anderson Cancer Center; Houston, Texas, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Fernandez-Duque+E%22">Fernandez-Duque E</searchLink>; Yale University; New Haven, Connecticut, 06520, USA.; Universidad Nacional de Formosa, Argentina Fundacion ECO, Formosa, Argentina.<br /><searchLink fieldCode="AU" term="%22Kanthaswamy+S%22">Kanthaswamy S</searchLink>; Arizona State University; Tempe, Arizona, 85281, USA.<br /><searchLink fieldCode="AU" term="%22Shiferaw+F%22">Shiferaw F</searchLink>; Hawassa University; Hawassa, 005, Ethiopia.<br /><searchLink fieldCode="AU" term="%22Wu+D%22">Wu D</searchLink>; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences; Kunming, Yunnan, 650223, China.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Center for Evolutionary & Organismal Biology, Zhejiang University School of Medicine, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Shao+Y%22">Shao Y</searchLink>; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences; Kunming, Yunnan, 650223, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Center for Evolutionary & Organismal Biology, Zhejiang University School of Medicine, Hangzhou, 310058, China.; Villum Center for Biodiversity Genomics, Section for Ecology and Evolution, Department of Biology, University of Copenhagen; Copenhagen, DK-2100, Denmark.; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, 650223, China.; Liangzhu Laboratory, Zhejiang University Medical Center; 1369 West Wenyi Road, Hangzhou, 311121, China.; Women's Hospital, School of Medicine, Zhejiang University; 1 Xueshi Road, Shangcheng District, Hangzhou, 310006, China.<br /><searchLink fieldCode="AU" term="%22Keyyu+JD%22">Keyyu JD</searchLink>; Tanzania Wildlife Research Institute (TAWIRI), Head Office; P.O.Box 661, Arusha, Tanzania.<br /><searchLink fieldCode="AU" term="%22Knauf+S%22">Knauf S</searchLink>; Institute of International Animal Health/One Health, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health; 17493 Greifswald - Isle of Riems, Germany.<br /><searchLink fieldCode="AU" term="%22Le+MD%22">Le MD</searchLink>; Department of Environmental Ecology, Faculty of Environmental Sciences, University of Science and Central Institute for Natural Resources and Environmental Studies, Vietnam National University; Hanoi, 100000, Vietnam.<br /><searchLink fieldCode="AU" term="%22Lizano+E%22">Lizano E</searchLink>; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Merker+S%22">Merker S</searchLink>; Department of Zoology, State Museum of Natural History Stuttgart; 70191 Stuttgart, Germany.<br /><searchLink fieldCode="AU" term="%22Navarro+A%22">Navarro A</searchLink>; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA) and Universitat Pompeu Fabra, Pg. Luís Companys 23, Barcelona, 08010, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology; Av. Doctor Aiguader, N88, Barcelona, 08003, Spain.; BarcelonaBeta Brain Research Center, Pasqual Maragall Foundation; C. Wellington 30, Barcelona, 08005, Spain.<br /><searchLink fieldCode="AU" term="%22Batallion+T%22">Batallion T</searchLink>; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark.<br /><searchLink fieldCode="AU" term="%22Nadler+T%22">Nadler T</searchLink>; Cuc Phuong Commune; Nho Quan District, Ninh Binh Province, 430000, Vietnam.<br /><searchLink fieldCode="AU" term="%22Khor+CC%22">Khor CC</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Mandai Nature; 80 Mandai Lake Road, Singapore 729826, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+P%22">Tan P</searchLink>; Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), 60 Biopolis Street, Genome, Singapore 138672, Republic of Singapore.; SingHealth Duke-NUS Institute of Precision Medicine (PRISM); Singapore 168582, Republic of Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School; Singapore 168582, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Lim+WK%22">Lim WK</searchLink>; SingHealth Duke-NUS Institute of Precision Medicine (PRISM); Singapore 168582, Republic of Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School; Singapore 168582, Republic of Singapore.; SingHealth Duke-NUS Genomic Medicine Centre; Singapore 168582, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Kitchener+AC%22">Kitchener AC</searchLink>; Department of Natural Sciences, National Museums Scotland; Chambers Street, Edinburgh, EH1 1JF, UK.; School of Geosciences, University of Edinburgh; Drummond Street, Edinburgh, EH8 9XP, UK.<br /><searchLink fieldCode="AU" term="%22Zinner+D%22">Zinner D</searchLink>; Cognitive Ethology Laboratory, Germany Primate Center, Leibniz Institute for Primate Research; 37077 Göttingen, Germany.; Department of Primate Cognition, Georg-August-Universität Göttingen; 37077 Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Gut+I%22">Gut I</searchLink>; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain.; Universitat Pompeu Fabra, Pg. Luís Companys 23, Barcelona, 08010, Spain.<br /><searchLink fieldCode="AU" term="%22Melin+A%22">Melin A</searchLink>; Leibniz Science Campus Primate Cognition; 37077 Göttingen, Germany.; Department of Anthropology & Archaeology and Department of Medical Genetics.<br /><searchLink fieldCode="AU" term="%22Guschanski+K%22">Guschanski K</searchLink>; Department of Ecology and Genetics, Animal Ecology, Uppsala University; SE-75236, Uppsala, Sweden.; Alberta Children's Hospital Research Institute; University of Calgary; 2500 University Dr NW T2N 1N4, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Schierup+MH%22">Schierup MH</searchLink>; Bioinformatics Research Centre, Aarhus University; Aarhus, 8000, Denmark.<br /><searchLink fieldCode="AU" term="%22Beck+RMD%22">Beck RMD</searchLink>; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Umapathy+G%22">Umapathy G</searchLink>; Academy of Scientific and Innovative Research (AcSIR); Ghaziabad, 201002, India.; Laboratory for the Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology; Hyderabad, 500007, India.<br /><searchLink fieldCode="AU" term="%22Roos+C%22">Roos C</searchLink>; Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh; Edinburgh, EH8 9XP, UK.<br /><searchLink fieldCode="AU" term="%22Boubli+JP%22">Boubli JP</searchLink>; School of Science, Engineering & Environment, University of Salford; Salford, M5 4WT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lek+M%22">Lek M</searchLink>; Gene Bank of Primates and Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research; Kellnerweg 4, 37077 Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Sunyaev+S%22">Sunyaev S</searchLink>; Department of Genetics, Yale School of Medicine; New Haven, Connecticut, 06520, USA.; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA.<br /><searchLink fieldCode="AU" term="%22O'Donnell+A%22">O'Donnell A</searchLink>; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA.; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School; Boston, Massachusetts, 02115, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Rehm+H%22">Rehm H</searchLink>; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard; Boston, Massachusetts, 02142, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School; Boston, Massachusetts, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.; Toyota Technological Institute at Chicago; Chicago, Illinois, 60637, USA.<br /><searchLink fieldCode="AU" term="%22Rogers+J%22">Rogers J</searchLink>; Human Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine; Houston, Texas, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Marques-Bonet+T%22">Marques-Bonet T</searchLink>; Institute of Evolutionary Biology (UPF-CSIC); PRBB, Dr. Aiguader 88, 08003 Barcelona, Spain.; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Baldiri i Reixac 4, 08028, Barcelona, Spain.; Institut Català de Paleontologia Miquel Crusafont, Universitat Autònoma de Barcelona, Barcelona, Spain; Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA) and Universitat Pompeu Fabra, Pg. Luís Companys 23, Barcelona, 08010, Spain.<br /><searchLink fieldCode="AU" term="%22Kai-How+Farh+K%22">Kai-How Farh K</searchLink>; Illumina Artificial Intelligence Laboratory, Illumina Inc.; Foster City, California, 94404, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2023 May 02. <i>Date of Electronic Publication: </i>2023 May 02.
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        Value: 10.1101/2023.05.01.538953
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      – TitleFull: The landscape of tolerated genetic variation in humans and primates.
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      – PersonEntity:
          Name:
            NameFull: Beck RMD
      – PersonEntity:
          Name:
            NameFull: Umapathy G
      – PersonEntity:
          Name:
            NameFull: Roos C
      – PersonEntity:
          Name:
            NameFull: Boubli JP
      – PersonEntity:
          Name:
            NameFull: Lek M
      – PersonEntity:
          Name:
            NameFull: Sunyaev S
      – PersonEntity:
          Name:
            NameFull: O'Donnell A
      – PersonEntity:
          Name:
            NameFull: Rehm H
      – PersonEntity:
          Name:
            NameFull: Xu J
      – PersonEntity:
          Name:
            NameFull: Rogers J
      – PersonEntity:
          Name:
            NameFull: Marques-Bonet T
      – PersonEntity:
          Name:
            NameFull: Kai-How Farh K
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 05
              Text: 2023 May 02
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1