Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys.

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Title: Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys.
Authors: Dubois V; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Basic and Translational Endocrinology (BaTE), Department of Basic and Applied Medical Sciences, Ghent University, Ghent, Belgium., Ciancia S; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium., Doms S; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium., El Kharraz S; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Sommers V; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Kim NR; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium., David K; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium., Van Dijck J; Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, Leuven, Belgium., Valle-Tenney R; Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, Leuven, Belgium., Maes C; Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, Leuven, Belgium., Antonio L; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium., Decallonne B; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium., Carmeliet G; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium., Claessens F; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Cools M; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.; Pediatric Endocrinology Service, Department of Pediatrics, Ghent University Hospital, Ghent, Belgium., Vanderschueren D; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.
Source: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research [J Bone Miner Res] 2023 Oct; Vol. 38 (10), pp. 1497-1508. Date of Electronic Publication: 2023 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8610640 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-4681 (Electronic) Linking ISSN: 08840431 NLM ISO Abbreviation: J Bone Miner Res Subsets: MEDLINE
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  Data: Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys.
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  Data: <searchLink fieldCode="AU" term="%22Dubois+V%22">Dubois V</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Basic and Translational Endocrinology (BaTE), Department of Basic and Applied Medical Sciences, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Ciancia+S%22">Ciancia S</searchLink>; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Doms+S%22">Doms S</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22El+Kharraz+S%22">El Kharraz S</searchLink>; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Sommers+V%22">Sommers V</searchLink>; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Kim+NR%22">Kim NR</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22David+K%22">David K</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Dijck+J%22">Van Dijck J</searchLink>; Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Valle-Tenney+R%22">Valle-Tenney R</searchLink>; Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Maes+C%22">Maes C</searchLink>; Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Antonio+L%22">Antonio L</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Decallonne+B%22">Decallonne B</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Carmeliet+G%22">Carmeliet G</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Claessens+F%22">Claessens F</searchLink>; Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Cools+M%22">Cools M</searchLink>; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.; Pediatric Endocrinology Service, Department of Pediatrics, Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Vanderschueren+D%22">Vanderschueren D</searchLink>; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism (Chrometa), KU Leuven, Leuven, Belgium.; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.
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  Data: <searchLink fieldCode="JN" term="%228610640%22">Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research</searchLink> [J Bone Miner Res] 2023 Oct; Vol. 38 (10), pp. 1497-1508. <i>Date of Electronic Publication: </i>2023 Jun 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8610640 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1523-4681 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208840431%22">08840431 </searchLink><i>NLM ISO Abbreviation: </i>J Bone Miner Res <i>Subsets: </i>MEDLINE
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        Value: 10.1002/jbmr.4832
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        Text: English
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      – TitleFull: Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys.
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