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Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion.

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Title: Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion.
Authors: Eser TM; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Baranov O; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Huth M; Institute of Computational Biology, Helmholtz Zentrum München, 85764, Neuherberg, Germany.; Center for Mathematics, Technische Universität München, 85748, Garching, Germany., Ahmed MIM; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Deák F; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Held K; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Lin L; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Pekayvaz K; Department of Medicine I, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 81377, Munich, Germany., Leunig A; Department of Medicine I, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 81377, Munich, Germany., Nicolai L; Department of Medicine I, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 81377, Munich, Germany., Pollakis G; Institute of Infection and Global Health, University of Liverpool, Liverpool, L69 2BE, UK., Buggert M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, 141 86, Stockholm, Sweden., Price DA; Division of Infection and Immunity, Cardiff University School of Medicine, University Hospital, Heath Park, Cardiff, CF14 4XN, UK.; Systems Immunity Research Institute, Cardiff University School of Medicine, University Hospital, Heath Park, Cardiff, CF14 4XN, UK., Rubio-Acero R; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany., Reich J; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany., Falk P; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany., Markgraf A; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany., Puchinger K; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany., Castelletti N; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Olbrich L; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Vanshylla K; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany., Klein F; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50937, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, 50931, Cologne, Germany., Wieser A; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany.; Max von Pettenkofer Institute for Hygiene and Medical Microbiology, LMU Munich, 81377, Munich, Germany., Hasenauer J; Institute of Computational Biology, Helmholtz Zentrum München, 85764, Neuherberg, Germany.; Center for Mathematics, Technische Universität München, 85748, Garching, Germany.; Faculty of Mathematics and Natural Sciences, University of Bonn, 53113, Bonn, Germany., Kroidl I; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Hoelscher M; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany., Geldmacher C; Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich, 81377, Munich, Germany. geldmacher@lrz.uni-muenchen.de.; German Center for Infection Research (DZIF), Partner Site Munich, 81377, Munich, Germany. geldmacher@lrz.uni-muenchen.de.
Source: Nature communications [Nat Commun] 2023 May 24; Vol. 14 (1), pp. 2952. Date of Electronic Publication: 2023 May 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Nucleocapsid-specific T cell responses associate with control of SARS-CoV-2 in the upper airways before seroconversion.
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