Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.
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| Title: | Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial. |
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| Authors: | Berger JS; Center for the Prevention of Cardiovascular Disease, NYU Grossman School of Medicine, New York, New York., Neal MD; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania., Kornblith LZ; Department of Surgery, University of California, San Francisco, San Francisco.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco., Gong MN; Albert Einstein College of Medicine, Bronx, New York., Reynolds HR; Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York., Cushman M; University of Vermont College of Medicine, Burlington., Althouse AD; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.; Now with Medtronic, Minneapolis, Minnesota., Lawler PR; Peter Munk Cardiac Centre, Toronto, Ontario, Canada., McVerry BJ; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Kim KS; College of Pharmacy, University of Illinois at Chicago, Chicago., Baumann Kreuziger L; Versity Blood Research Institute, Milwaukee, Wisconsin., Solomon SD; Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Kosiborod MN; Saint Luke's Mid America Heart Institute, University of Missouri, Kansas City., Berry SM; Berry Consultants, LLC, Austin, Texas., Bochicchio GV; Washington University School of Medicine, St Louis, Missouri., Contoli M; Department of Translational Medicine, Università di Ferrara, Ferrara, Italy., Farkouh ME; Peter Munk Cardiac Centre, Toronto, Ontario, Canada., Froess JD; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania., Gandotra S; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama, Birmingham., Greenstein Y; Rutgers New Jersey Medical School, Newark., Hade EM; Division of Biostatistics, Department of Population Health, NYU Grossman School of Medicine, New York, New York., Hanna N; Ascension St John Clinical Research Institute, Tulsa, Oklahoma., Hudock K; University of Cincinnati Medical Center, Cincinnati, Ohio., Hyzy RC; Division of Pulmonary and Critical Care, Department of Medicine, University of Michigan, Ann Arbor., Ibáñez Estéllez F; Hospital Emergencias Enfermera Isabel Zendal, Madrid, Spain., Iovine N; Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida, Gainesville., Khanna AK; Perioperative Outcomes and Informatics Collaborative, Wake Forest University School of Medicine, Winston-Salem, North Carolina.; Outcomes Research Consortium, Cleveland, Ohio., Khatri P; University of Cincinnati Medical Center, Cincinnati, Ohio., Kirwan BA; Socar Research SA, Nyon, Switzerland., Kutcher ME; University of Mississippi Medical Center, Jackson., Leifer E; National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland., Lim G; Ronald Reagan UCLA Medical Center, Los Angeles, California., Lopes RD; Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham., Lopez-Sendon JL; IdiPaz Research Institute, Hospital Universitario La Paz, Madrid, Spain., Luther JF; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania., Nigro Maia L; Fundação Faculdade Regional De Medicina De São José Do Rio Preto, São José do Rio Preto, Brazil., Quigley JG; Division of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago., Wahid L; Division of Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina., Wilson JG; Stanford University Medical Center, Stanford, California., Zarychanski R; Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada., Kindzelski A; National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland., Geraci MW; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Hochman JS; Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York. |
| Corporate Authors: | ACTIV-4a Investigators |
| Source: | JAMA network open [JAMA Netw Open] 2023 May 01; Vol. 6 (5), pp. e2314428. Date of Electronic Publication: 2023 May 01. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37227729 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Berger+JS%22">Berger JS</searchLink>; Center for the Prevention of Cardiovascular Disease, NYU Grossman School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Neal+MD%22">Neal MD</searchLink>; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Kornblith+LZ%22">Kornblith LZ</searchLink>; Department of Surgery, University of California, San Francisco, San Francisco.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco.<br /><searchLink fieldCode="AU" term="%22Gong+MN%22">Gong MN</searchLink>; Albert Einstein College of Medicine, Bronx, New York.<br /><searchLink fieldCode="AU" term="%22Reynolds+HR%22">Reynolds HR</searchLink>; Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Cushman+M%22">Cushman M</searchLink>; University of Vermont College of Medicine, Burlington.<br /><searchLink fieldCode="AU" term="%22Althouse+AD%22">Althouse AD</searchLink>; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.; Now with Medtronic, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Lawler+PR%22">Lawler PR</searchLink>; Peter Munk Cardiac Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22McVerry+BJ%22">McVerry BJ</searchLink>; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Kim+KS%22">Kim KS</searchLink>; College of Pharmacy, University of Illinois at Chicago, Chicago.<br /><searchLink fieldCode="AU" term="%22Baumann+Kreuziger+L%22">Baumann Kreuziger L</searchLink>; Versity Blood Research Institute, Milwaukee, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Solomon+SD%22">Solomon SD</searchLink>; Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kosiborod+MN%22">Kosiborod MN</searchLink>; Saint Luke's Mid America Heart Institute, University of Missouri, Kansas City.<br /><searchLink fieldCode="AU" term="%22Berry+SM%22">Berry SM</searchLink>; Berry Consultants, LLC, Austin, Texas.<br /><searchLink fieldCode="AU" term="%22Bochicchio+GV%22">Bochicchio GV</searchLink>; Washington University School of Medicine, St Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Contoli+M%22">Contoli M</searchLink>; Department of Translational Medicine, Università di Ferrara, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Farkouh+ME%22">Farkouh ME</searchLink>; Peter Munk Cardiac Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Froess+JD%22">Froess JD</searchLink>; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Gandotra+S%22">Gandotra S</searchLink>; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama, Birmingham.<br /><searchLink fieldCode="AU" term="%22Greenstein+Y%22">Greenstein Y</searchLink>; Rutgers New Jersey Medical School, Newark.<br /><searchLink fieldCode="AU" term="%22Hade+EM%22">Hade EM</searchLink>; Division of Biostatistics, Department of Population Health, NYU Grossman School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Hanna+N%22">Hanna N</searchLink>; Ascension St John Clinical Research Institute, Tulsa, Oklahoma.<br /><searchLink fieldCode="AU" term="%22Hudock+K%22">Hudock K</searchLink>; University of Cincinnati Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Hyzy+RC%22">Hyzy RC</searchLink>; Division of Pulmonary and Critical Care, Department of Medicine, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Ibáñez+Estéllez+F%22">Ibáñez Estéllez F</searchLink>; Hospital Emergencias Enfermera Isabel Zendal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Iovine+N%22">Iovine N</searchLink>; Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida, Gainesville.<br /><searchLink fieldCode="AU" term="%22Khanna+AK%22">Khanna AK</searchLink>; Perioperative Outcomes and Informatics Collaborative, Wake Forest University School of Medicine, Winston-Salem, North Carolina.; Outcomes Research Consortium, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Khatri+P%22">Khatri P</searchLink>; University of Cincinnati Medical Center, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Kirwan+BA%22">Kirwan BA</searchLink>; Socar Research SA, Nyon, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kutcher+ME%22">Kutcher ME</searchLink>; University of Mississippi Medical Center, Jackson.<br /><searchLink fieldCode="AU" term="%22Leifer+E%22">Leifer E</searchLink>; National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Lim+G%22">Lim G</searchLink>; Ronald Reagan UCLA Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Lopes+RD%22">Lopes RD</searchLink>; Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham.<br /><searchLink fieldCode="AU" term="%22Lopez-Sendon+JL%22">Lopez-Sendon JL</searchLink>; IdiPaz Research Institute, Hospital Universitario La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Luther+JF%22">Luther JF</searchLink>; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Nigro+Maia+L%22">Nigro Maia L</searchLink>; Fundação Faculdade Regional De Medicina De São José Do Rio Preto, São José do Rio Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22Quigley+JG%22">Quigley JG</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago.<br /><searchLink fieldCode="AU" term="%22Wahid+L%22">Wahid L</searchLink>; Division of Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina.<br /><searchLink fieldCode="AU" term="%22Wilson+JG%22">Wilson JG</searchLink>; Stanford University Medical Center, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Zarychanski+R%22">Zarychanski R</searchLink>; Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.<br /><searchLink fieldCode="AU" term="%22Kindzelski+A%22">Kindzelski A</searchLink>; National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Geraci+MW%22">Geraci MW</searchLink>; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hochman+JS%22">Hochman JS</searchLink>; Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22ACTIV-4a+Investigators%22">ACTIV-4a Investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101729235%22">JAMA network open</searchLink> [JAMA Netw Open] 2023 May 01; Vol. 6 (5), pp. e2314428. <i>Date of Electronic Publication: </i>2023 May 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101729235 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2574-3805 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225743805%22">25743805 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Netw Open <i>Subsets: </i>MEDLINE |
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