Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.

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Title: Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.
Authors: Berger JS; Center for the Prevention of Cardiovascular Disease, NYU Grossman School of Medicine, New York, New York., Neal MD; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania., Kornblith LZ; Department of Surgery, University of California, San Francisco, San Francisco.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco., Gong MN; Albert Einstein College of Medicine, Bronx, New York., Reynolds HR; Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York., Cushman M; University of Vermont College of Medicine, Burlington., Althouse AD; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.; Now with Medtronic, Minneapolis, Minnesota., Lawler PR; Peter Munk Cardiac Centre, Toronto, Ontario, Canada., McVerry BJ; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Kim KS; College of Pharmacy, University of Illinois at Chicago, Chicago., Baumann Kreuziger L; Versity Blood Research Institute, Milwaukee, Wisconsin., Solomon SD; Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Kosiborod MN; Saint Luke's Mid America Heart Institute, University of Missouri, Kansas City., Berry SM; Berry Consultants, LLC, Austin, Texas., Bochicchio GV; Washington University School of Medicine, St Louis, Missouri., Contoli M; Department of Translational Medicine, Università di Ferrara, Ferrara, Italy., Farkouh ME; Peter Munk Cardiac Centre, Toronto, Ontario, Canada., Froess JD; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania., Gandotra S; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama, Birmingham., Greenstein Y; Rutgers New Jersey Medical School, Newark., Hade EM; Division of Biostatistics, Department of Population Health, NYU Grossman School of Medicine, New York, New York., Hanna N; Ascension St John Clinical Research Institute, Tulsa, Oklahoma., Hudock K; University of Cincinnati Medical Center, Cincinnati, Ohio., Hyzy RC; Division of Pulmonary and Critical Care, Department of Medicine, University of Michigan, Ann Arbor., Ibáñez Estéllez F; Hospital Emergencias Enfermera Isabel Zendal, Madrid, Spain., Iovine N; Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida, Gainesville., Khanna AK; Perioperative Outcomes and Informatics Collaborative, Wake Forest University School of Medicine, Winston-Salem, North Carolina.; Outcomes Research Consortium, Cleveland, Ohio., Khatri P; University of Cincinnati Medical Center, Cincinnati, Ohio., Kirwan BA; Socar Research SA, Nyon, Switzerland., Kutcher ME; University of Mississippi Medical Center, Jackson., Leifer E; National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland., Lim G; Ronald Reagan UCLA Medical Center, Los Angeles, California., Lopes RD; Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham., Lopez-Sendon JL; IdiPaz Research Institute, Hospital Universitario La Paz, Madrid, Spain., Luther JF; Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania., Nigro Maia L; Fundação Faculdade Regional De Medicina De São José Do Rio Preto, São José do Rio Preto, Brazil., Quigley JG; Division of Hematology and Oncology, Department of Medicine, University of Illinois at Chicago., Wahid L; Division of Internal Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina., Wilson JG; Stanford University Medical Center, Stanford, California., Zarychanski R; Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada., Kindzelski A; National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland., Geraci MW; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Hochman JS; Division of Cardiology, Department of Medicine, NYU Grossman School of Medicine, New York, New York.
Corporate Authors: ACTIV-4a Investigators
Source: JAMA network open [JAMA Netw Open] 2023 May 01; Vol. 6 (5), pp. e2314428. Date of Electronic Publication: 2023 May 01.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
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  Data: Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.
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Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.; Now with Medtronic, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Lawler+PR%22">Lawler PR</searchLink>; Peter Munk Cardiac Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22McVerry+BJ%22">McVerry BJ</searchLink>; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Kim+KS%22">Kim KS</searchLink>; College of Pharmacy, University of Illinois at Chicago, Chicago.<br /><searchLink fieldCode="AU" term="%22Baumann+Kreuziger+L%22">Baumann Kreuziger L</searchLink>; Versity Blood Research Institute, Milwaukee, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Solomon+SD%22">Solomon SD</searchLink>; Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kosiborod+MN%22">Kosiborod MN</searchLink>; 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