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Metabolism of (R)-Praziquantel versus the Activation of a Parasite Transient Receptor Potential Melastatin Ion Channel.

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Title: Metabolism of (R)-Praziquantel versus the Activation of a Parasite Transient Receptor Potential Melastatin Ion Channel.
Authors: Friedrich L; Global Research & Development, Merck Healthcare KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany., Park SK; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee WI, 53226, USA., Ballard P; PB DMPK Consulting Ltd., Chinley, SK236BQ, UK., Ho Baeurle TH; Site Management-Analytics, Merck Healthcare KGaA, 64293, Darmstadt, Germany., Maillard D; Central Process Development-Downstream Processing Services, Merck Electronics KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany., Bödding M; Merck Healthcare KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany., Keiser J; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Kreuzstr. 2, 4123, Allschwil, Switzerland.; Helminth Drug Development Unit, University of Basel, Basel, Switzerland., Marchant JS; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee WI, 53226, USA., Spangenberg T; Global Health Institute of Merck, Ares Trading S.A., a subsidiary of Merck KGaA, Darmstadt Germany, 1262, Eysins, Switzerland.
Source: ChemMedChem [ChemMedChem] 2023 Sep 15; Vol. 18 (18), pp. e202300140. Date of Electronic Publication: 2023 Jun 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metabolism of (R)-Praziquantel versus the Activation of a Parasite Transient Receptor Potential Melastatin Ion Channel.
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  Data: <searchLink fieldCode="AU" term="%22Friedrich+L%22">Friedrich L</searchLink>; Global Research & Development, Merck Healthcare KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Park+SK%22">Park SK</searchLink>; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee WI, 53226, USA.<br /><searchLink fieldCode="AU" term="%22Ballard+P%22">Ballard P</searchLink>; PB DMPK Consulting Ltd., Chinley, SK236BQ, UK.<br /><searchLink fieldCode="AU" term="%22Ho+Baeurle+TH%22">Ho Baeurle TH</searchLink>; Site Management-Analytics, Merck Healthcare KGaA, 64293, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Maillard+D%22">Maillard D</searchLink>; Central Process Development-Downstream Processing Services, Merck Electronics KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Bödding+M%22">Bödding M</searchLink>; Merck Healthcare KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany.<br /><searchLink fieldCode="AU" term="%22Keiser+J%22">Keiser J</searchLink>; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Kreuzstr. 2, 4123, Allschwil, Switzerland.; Helminth Drug Development Unit, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marchant+JS%22">Marchant JS</searchLink>; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee WI, 53226, USA.<br /><searchLink fieldCode="AU" term="%22Spangenberg+T%22">Spangenberg T</searchLink>; Global Health Institute of Merck, Ares Trading S.A., a subsidiary of Merck KGaA, Darmstadt Germany, 1262, Eysins, Switzerland.
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