Metabolism of (R)-Praziquantel versus the Activation of a Parasite Transient Receptor Potential Melastatin Ion Channel.
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| Title: | Metabolism of (R)-Praziquantel versus the Activation of a Parasite Transient Receptor Potential Melastatin Ion Channel. |
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| Authors: | Friedrich L; Global Research & Development, Merck Healthcare KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany., Park SK; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee WI, 53226, USA., Ballard P; PB DMPK Consulting Ltd., Chinley, SK236BQ, UK., Ho Baeurle TH; Site Management-Analytics, Merck Healthcare KGaA, 64293, Darmstadt, Germany., Maillard D; Central Process Development-Downstream Processing Services, Merck Electronics KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany., Bödding M; Merck Healthcare KGaA, Frankfurter Str. 250, 64293, Darmstadt, Germany., Keiser J; Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Kreuzstr. 2, 4123, Allschwil, Switzerland.; Helminth Drug Development Unit, University of Basel, Basel, Switzerland., Marchant JS; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee WI, 53226, USA., Spangenberg T; Global Health Institute of Merck, Ares Trading S.A., a subsidiary of Merck KGaA, Darmstadt Germany, 1262, Eysins, Switzerland. |
| Source: | ChemMedChem [ChemMedChem] 2023 Sep 15; Vol. 18 (18), pp. e202300140. Date of Electronic Publication: 2023 Jun 15. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1860-7187 |
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| DOI: | 10.1002/cmdc.202300140 |