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An integrated cell atlas of the lung in health and disease.

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Title: An integrated cell atlas of the lung in health and disease.
Authors: Sikkema L; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany., Ramírez-Suástegui C; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA., Strobl DC; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Institute of Clinical Chemistry and Pathobiochemistry, TUM School of Medicine, Technical University of Munich, Munich, Germany., Gillett TE; Experimental Pulmonary and Inflammatory Research, Department of Pathology and Medical Biology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Zappia L; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Department of Mathematics, Technical University of Munich, Garching, Germany., Madissoon E; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Markov NS; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Zaragosi LE; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France., Ji Y; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany., Ansari M; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany., Arguel MJ; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France., Apperloo L; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Banchero M; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Bécavin C; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France., Berg M; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Chichelnitskiy E; Institute for Transplant Immunology, Hannover Medical School, Hannover, Germany., Chung MI; Translational Genomics Research Institute, Phoenix, AZ, USA., Collin A; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France.; 3IA Côte d'Azur, Nice, France., Gay ACA; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Gote-Schniering J; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany., Hooshiar Kashani B; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany., Inecik K; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany., Jain M; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Kapellos TS; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.; Department of Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Kole TM; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Leroy S; Pulmonology Department, Fédération Hospitalo-Universitaire OncoAge, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, Nice, France., Mayr CH; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany., Oliver AJ; Wellcome Sanger Institute, Hinxton, Cambridge, UK., von Papen M; Research, Development and Innovation, Comma Soft, Bonn, Germany., Peter L; Translational Genomics Research Institute, Phoenix, AZ, USA., Taylor CJ; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Walzthoeni T; Core Facility Genomics, Helmholtz Center Munich, Munich, Germany., Xu C; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Bui LT; Translational Genomics Research Institute, Phoenix, AZ, USA., De Donno C; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Dony L; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany.; Department of Translational Psychiatry, Max Planck Institute of Psychiatry and International Max Planck Research School for Translational Psychiatry, Munich, Germany., Faiz A; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; School of Life Sciences, Respiratory Bioinformatics and Molecular Biology, University of Technology Sydney, Sydney, Australia., Guo M; Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, US., Gutierrez AJ; Translational Genomics Research Institute, Phoenix, AZ, USA., Heumos L; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany.; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany., Huang N; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Ibarra IL; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Jackson ND; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA., Kadur Lakshminarasimha Murthy P; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA.; Department of Pharmacology and Regenerative Medicine, University of Illinois Chicago, Chicago, IL, USA., Lotfollahi M; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Tabib T; Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Talavera-López C; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Division of Infectious Diseases and Tropical Medicine, Klinikum der Lüdwig-Maximilians-Universität, Munich, Germany., Travaglini KJ; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Allen Institute for Brain Science, Seattle, WA, USA., Wilbrey-Clark A; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Worlock KB; Department of Respiratory Medicine, Division of Medicine, University College London, London, UK., Yoshida M; Department of Respiratory Medicine, Division of Medicine, University College London, London, UK., van den Berge M; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Bossé Y; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Department of Molecular Medicine, Laval University, Quebec City, Quebec, Canada., Desai TJ; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Eickelberg O; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Kaminski N; Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA., Krasnow MA; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Lafyatis R; Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Nikolic MZ; Department of Respiratory Medicine, Division of Medicine, University College London, London, UK., Powell JE; Garvan Institute of Medical Research, Sydney, New South Wales, Australia.; Cellular Genomics Futures Institute, University of New South Wales, Sydney, New South Wales, Australia., Rajagopal J; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA., Rojas M; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, USA., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cellular and Tissue Genomics, Genentech, South San Francisco, CA, USA., Seibold MA; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.; Department of Pediatrics, National Jewish Health, Denver, CO, USA.; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO, USA., Sheppard D; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA., Shepherd DP; Department of Physics and Center for Biological Physics, Arizona State University, Tempe, AZ, USA., Sin DD; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Timens W; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Tsankov AM; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Whitsett J; Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Xu Y; Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Banovich NE; Translational Genomics Research Institute, Phoenix, AZ, USA., Barbry P; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France.; 3IA Côte d'Azur, Nice, France., Duong TE; Department of Pediatrics, Division of Respiratory Medicine, University of California, San Diego, La Jolla, CA, USA., Falk CS; Institute for Transplant Immunology, Hannover Medical School, Hannover, Germany., Meyer KB; Wellcome Sanger Institute, Hinxton, Cambridge, UK., Kropski JA; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Pe'er D; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Schiller HB; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany., Tata PR; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA., Schultze JL; Department of Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen and University of Bonn, Bonn, Germany., Teichmann SA; Wellcome Sanger Institute, Hinxton, Cambridge, UK.; Department of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK., Misharin AV; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Nawijn MC; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Luecken MD; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany. malte.luecken@helmholtz-munich.de.; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany. malte.luecken@helmholtz-munich.de., Theis FJ; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; Department of Mathematics, Technical University of Munich, Garching, Germany. fabian.theis@helmholtz-munich.de.
Corporate Authors: Lung Biological Network Consortium
Source: Nature medicine [Nat Med] 2023 Jun; Vol. 29 (6), pp. 1563-1577. Date of Electronic Publication: 2023 Jun 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An integrated cell atlas of the lung in health and disease.
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  Data: <searchLink fieldCode="AU" term="%22Sikkema+L%22">Sikkema L</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ramírez-Suástegui+C%22">Ramírez-Suástegui C</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Strobl+DC%22">Strobl DC</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Institute of Clinical Chemistry and Pathobiochemistry, TUM School of Medicine, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gillett+TE%22">Gillett TE</searchLink>; Experimental Pulmonary and Inflammatory Research, Department of Pathology and Medical Biology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Zappia+L%22">Zappia L</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Department of Mathematics, Technical University of Munich, Garching, Germany.<br /><searchLink fieldCode="AU" term="%22Madissoon+E%22">Madissoon E</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Markov+NS%22">Markov NS</searchLink>; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Zaragosi+LE%22">Zaragosi LE</searchLink>; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France.<br /><searchLink fieldCode="AU" term="%22Ji+Y%22">Ji Y</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ansari+M%22">Ansari M</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Arguel+MJ%22">Arguel MJ</searchLink>; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France.<br /><searchLink fieldCode="AU" term="%22Apperloo+L%22">Apperloo L</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Banchero+M%22">Banchero M</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bécavin+C%22">Bécavin C</searchLink>; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France.<br /><searchLink fieldCode="AU" term="%22Berg+M%22">Berg M</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Chichelnitskiy+E%22">Chichelnitskiy E</searchLink>; Institute for Transplant Immunology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Chung+MI%22">Chung MI</searchLink>; Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Collin+A%22">Collin A</searchLink>; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France.; 3IA Côte d'Azur, Nice, France.<br /><searchLink fieldCode="AU" term="%22Gay+ACA%22">Gay ACA</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Gote-Schniering+J%22">Gote-Schniering J</searchLink>; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Hooshiar+Kashani+B%22">Hooshiar Kashani B</searchLink>; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Inecik+K%22">Inecik K</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Jain+M%22">Jain M</searchLink>; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Kapellos+TS%22">Kapellos TS</searchLink>; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.; Department of Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Kole+TM%22">Kole TM</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Leroy+S%22">Leroy S</searchLink>; Pulmonology Department, Fédération Hospitalo-Universitaire OncoAge, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, Nice, France.<br /><searchLink fieldCode="AU" term="%22Mayr+CH%22">Mayr CH</searchLink>; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Oliver+AJ%22">Oliver AJ</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22von+Papen+M%22">von Papen M</searchLink>; Research, Development and Innovation, Comma Soft, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Peter+L%22">Peter L</searchLink>; Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+CJ%22">Taylor CJ</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Walzthoeni+T%22">Walzthoeni T</searchLink>; Core Facility Genomics, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bui+LT%22">Bui LT</searchLink>; Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22De+Donno+C%22">De Donno C</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Dony+L%22">Dony L</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany.; Department of Translational Psychiatry, Max Planck Institute of Psychiatry and International Max Planck Research School for Translational Psychiatry, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Faiz+A%22">Faiz A</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; School of Life Sciences, Respiratory Bioinformatics and Molecular Biology, University of Technology Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Guo+M%22">Guo M</searchLink>; Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, US.<br /><searchLink fieldCode="AU" term="%22Gutierrez+AJ%22">Gutierrez AJ</searchLink>; Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Heumos+L%22">Heumos L</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany.; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Huang+N%22">Huang N</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ibarra+IL%22">Ibarra IL</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Jackson+ND%22">Jackson ND</searchLink>; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.<br /><searchLink fieldCode="AU" term="%22Kadur+Lakshminarasimha+Murthy+P%22">Kadur Lakshminarasimha Murthy P</searchLink>; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA.; Department of Pharmacology and Regenerative Medicine, University of Illinois Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Lotfollahi+M%22">Lotfollahi M</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Wellcome Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tabib+T%22">Tabib T</searchLink>; Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Talavera-López+C%22">Talavera-López C</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; Division of Infectious Diseases and Tropical Medicine, Klinikum der Lüdwig-Maximilians-Universität, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Travaglini+KJ%22">Travaglini KJ</searchLink>; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Allen Institute for Brain Science, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Wilbrey-Clark+A%22">Wilbrey-Clark A</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Worlock+KB%22">Worlock KB</searchLink>; Department of Respiratory Medicine, Division of Medicine, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Yoshida+M%22">Yoshida M</searchLink>; Department of Respiratory Medicine, Division of Medicine, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22van+den+Berge+M%22">van den Berge M</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bossé+Y%22">Bossé Y</searchLink>; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Department of Molecular Medicine, Laval University, Quebec City, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Desai+TJ%22">Desai TJ</searchLink>; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Eickelberg+O%22">Eickelberg O</searchLink>; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kaminski+N%22">Kaminski N</searchLink>; Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Krasnow+MA%22">Krasnow MA</searchLink>; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lafyatis+R%22">Lafyatis R</searchLink>; Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Nikolic+MZ%22">Nikolic MZ</searchLink>; Department of Respiratory Medicine, Division of Medicine, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Powell+JE%22">Powell JE</searchLink>; Garvan Institute of Medical Research, Sydney, New South Wales, Australia.; Cellular Genomics Futures Institute, University of New South Wales, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Rajagopal+J%22">Rajagopal J</searchLink>; Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rojas+M%22">Rojas M</searchLink>; Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Rozenblatt-Rosen+O%22">Rozenblatt-Rosen O</searchLink>; Klarman Cell Observatory, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cellular and Tissue Genomics, Genentech, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Seibold+MA%22">Seibold MA</searchLink>; Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, USA.; Department of Pediatrics, National Jewish Health, Denver, CO, USA.; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Sheppard+D%22">Sheppard D</searchLink>; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shepherd+DP%22">Shepherd DP</searchLink>; Department of Physics and Center for Biological Physics, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Sin+DD%22">Sin DD</searchLink>; Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Timens+W%22">Timens W</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Tsankov+AM%22">Tsankov AM</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Whitsett+J%22">Whitsett J</searchLink>; Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Banovich+NE%22">Banovich NE</searchLink>; Translational Genomics Research Institute, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Barbry+P%22">Barbry P</searchLink>; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur and Centre National de la Recherche Scientifique, Valbonne, France.; 3IA Côte d'Azur, Nice, France.<br /><searchLink fieldCode="AU" term="%22Duong+TE%22">Duong TE</searchLink>; Department of Pediatrics, Division of Respiratory Medicine, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Falk+CS%22">Falk CS</searchLink>; Institute for Transplant Immunology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+KB%22">Meyer KB</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kropski+JA%22">Kropski JA</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Pe'er+D%22">Pe'er D</searchLink>; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Schiller+HB%22">Schiller HB</searchLink>; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Tata+PR%22">Tata PR</searchLink>; Department of Cell Biology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Schultze+JL%22">Schultze JL</searchLink>; Department of Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen and University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Teichmann+SA%22">Teichmann SA</searchLink>; Wellcome Sanger Institute, Hinxton, Cambridge, UK.; Department of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Misharin+AV%22">Misharin AV</searchLink>; Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Nawijn+MC%22">Nawijn MC</searchLink>; Groningen Research Institute for Asthma and COPD, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Luecken+MD%22">Luecken MD</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany. malte.luecken@helmholtz-munich.de.; Institute of Lung Health and Immunity (a member of the German Center for Lung Research) and Comprehensive Pneumology Center with the CPC-M bioArchive, Helmholtz Center Munich, Munich, Germany. malte.luecken@helmholtz-munich.de.<br /><searchLink fieldCode="AU" term="%22Theis+FJ%22">Theis FJ</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; TUM School of Life Sciences, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; Department of Mathematics, Technical University of Munich, Garching, Germany. fabian.theis@helmholtz-munich.de.
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  Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2023 Jun; Vol. 29 (6), pp. 1563-1577. <i>Date of Electronic Publication: </i>2023 Jun 08.
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