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Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.

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Title: Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.
Authors: Ma F; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA., Plazyo O; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Billi AC; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Tsoi LC; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Xing X; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Wasikowski R; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Gharaee-Kermani M; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Hile G; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Jiang Y; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Harms PW; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Xing E; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Kirma J; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Xi J; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Hsu JE; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Sarkar MK; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Chung Y; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Di Domizio J; Department of Dermatology, University Hospital of Lausanne, 1011, Lausanne, Switzerland., Gilliet M; Department of Dermatology, University Hospital of Lausanne, 1011, Lausanne, Switzerland., Ward NL; Department of Dermatology, Case Western Reserve University, Cleveland, OH, 44106, USA., Maverakis E; Department of Dermatology, University of California Davis, Sacramento, CA, USA., Klechevsky E; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA., Voorhees JJ; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Elder JT; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.; Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI, 48105, USA., Lee JH; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Kahlenberg JM; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA., Pellegrini M; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, 90095, USA., Modlin RL; Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA, 90095, USA.; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA., Gudjonsson JE; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA. johanng@med.umich.edu.
Source: Nature communications [Nat Commun] 2023 Jun 12; Vol. 14 (1), pp. 3455. Date of Electronic Publication: 2023 Jun 12.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.
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  Data: <searchLink fieldCode="AU" term="%22Ma+F%22">Ma F</searchLink>; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Plazyo+O%22">Plazyo O</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Billi+AC%22">Billi AC</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Tsoi+LC%22">Tsoi LC</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Xing+X%22">Xing X</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Wasikowski+R%22">Wasikowski R</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Gharaee-Kermani+M%22">Gharaee-Kermani M</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Hile+G%22">Hile G</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Harms+PW%22">Harms PW</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Xing+E%22">Xing E</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Kirma+J%22">Kirma J</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Xi+J%22">Xi J</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Hsu+JE%22">Hsu JE</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Sarkar+MK%22">Sarkar MK</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Chung+Y%22">Chung Y</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Di+Domizio+J%22">Di Domizio J</searchLink>; Department of Dermatology, University Hospital of Lausanne, 1011, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gilliet+M%22">Gilliet M</searchLink>; Department of Dermatology, University Hospital of Lausanne, 1011, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ward+NL%22">Ward NL</searchLink>; Department of Dermatology, Case Western Reserve University, Cleveland, OH, 44106, USA.<br /><searchLink fieldCode="AU" term="%22Maverakis+E%22">Maverakis E</searchLink>; Department of Dermatology, University of California Davis, Sacramento, CA, USA.<br /><searchLink fieldCode="AU" term="%22Klechevsky+E%22">Klechevsky E</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, 63110, USA.<br /><searchLink fieldCode="AU" term="%22Voorhees+JJ%22">Voorhees JJ</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Elder+JT%22">Elder JT</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.; Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI, 48105, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Kahlenberg+JM%22">Kahlenberg JM</searchLink>; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA.<br /><searchLink fieldCode="AU" term="%22Pellegrini+M%22">Pellegrini M</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Modlin+RL%22">Modlin RL</searchLink>; Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA, 90095, USA.; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA.<br /><searchLink fieldCode="AU" term="%22Gudjonsson+JE%22">Gudjonsson JE</searchLink>; Department of Dermatology, University of Michigan, Ann Arbor, MI, 48109, USA. johanng@med.umich.edu.
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