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Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.

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Title: Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.
Authors: Peters CW; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Hanlon KS; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Neurology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA., Ivanchenko MV; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Zinn E; Grousbeck Gene Therapy Center, Schepens Eye Research Institute, Massachusetts Eye and Ear, Boston, MA 02114, USA., Linarte EF; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Li Y; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA., Levy JM; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA., Liu DR; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA., Kleinstiver BP; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA., Indzhykulian AA; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, MA 02114, USA., Corey DP; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: dcorey@hms.harvard.edu.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2023 Aug 02; Vol. 31 (8), pp. 2439-2453. Date of Electronic Publication: 2023 Jun 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.
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  Data: <searchLink fieldCode="AU" term="%22Peters+CW%22">Peters CW</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Hanlon+KS%22">Hanlon KS</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Neurology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Ivanchenko+MV%22">Ivanchenko MV</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Zinn+E%22">Zinn E</searchLink>; Grousbeck Gene Therapy Center, Schepens Eye Research Institute, Massachusetts Eye and Ear, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Linarte+EF%22">Linarte EF</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Levy+JM%22">Levy JM</searchLink>; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22Liu+DR%22">Liu DR</searchLink>; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA.<br /><searchLink fieldCode="AU" term="%22Kleinstiver+BP%22">Kleinstiver BP</searchLink>; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Indzhykulian+AA%22">Indzhykulian AA</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School and Massachusetts Eye and Ear, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Corey+DP%22">Corey DP</searchLink>; Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: dcorey@hms.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2023 Aug 02; Vol. 31 (8), pp. 2439-2453. <i>Date of Electronic Publication: </i>2023 Jun 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ymthe.2023.06.007
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        Text: English
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              Text: 2023 Aug 02
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