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Disruption of cortical cell type composition and function underlies diabetes-associated cognitive decline.

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Title: Disruption of cortical cell type composition and function underlies diabetes-associated cognitive decline.
Authors: Little K; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK., Singh A; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK., Del Marco A; Division of Physiology, School of Medicine, University of Cadiz, Cadiz, Spain.; Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz (INIBICA), Cadiz, Spain., Llorián-Salvador M; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK.; Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain., Vargas-Soria M; Division of Physiology, School of Medicine, University of Cadiz, Cadiz, Spain.; Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz (INIBICA), Cadiz, Spain., Turch-Anguera M; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Cell Signaling and Apoptosis Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Departament de Bioquímica i Biologia Molecular i Institut de Neurociències, Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; Centro de Investigación en Red en Enfermedades Neurodegenerativas (CIBERNED - ISCII), Madrid, Spain., Solé M; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Cell Signaling and Apoptosis Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Departament de Bioquímica i Biologia Molecular i Institut de Neurociències, Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; Centro de Investigación en Red en Enfermedades Neurodegenerativas (CIBERNED - ISCII), Madrid, Spain., Bakker N; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands., Scullion S; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK., Comella JX; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Cell Signaling and Apoptosis Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Departament de Bioquímica i Biologia Molecular i Institut de Neurociències, Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; Centro de Investigación en Red en Enfermedades Neurodegenerativas (CIBERNED - ISCII), Madrid, Spain., Klaassen I; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands., Simó R; Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM-ISCIII), Madrid, Spain., Garcia-Alloza M; Division of Physiology, School of Medicine, University of Cadiz, Cadiz, Spain. monica.garcia@uca.es.; Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz (INIBICA), Cadiz, Spain. monica.garcia@uca.es., Tiwari VK; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK. tiwari@health.sdu.dk.; Institute of Molecular Medicine, University of Southern Denmark, Odense C, Denmark. tiwari@health.sdu.dk.; Danish Institute for Advanced Study (DIAS), Odense M, Denmark. tiwari@health.sdu.dk.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. tiwari@health.sdu.dk., Stitt AW; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK. a.stitt@qub.ac.uk.
Corporate Authors: RECOGNISED consortium
Source: Diabetologia [Diabetologia] 2023 Aug; Vol. 66 (8), pp. 1557-1575. Date of Electronic Publication: 2023 Jun 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Disruption of cortical cell type composition and function underlies diabetes-associated cognitive decline.
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  Data: <searchLink fieldCode="AU" term="%22Little+K%22">Little K</searchLink>; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Singh+A%22">Singh A</searchLink>; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Del+Marco+A%22">Del Marco A</searchLink>; Division of Physiology, School of Medicine, University of Cadiz, Cadiz, Spain.; Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz (INIBICA), Cadiz, Spain.<br /><searchLink fieldCode="AU" term="%22Llorián-Salvador+M%22">Llorián-Salvador M</searchLink>; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK.; Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Vargas-Soria+M%22">Vargas-Soria M</searchLink>; Division of Physiology, School of Medicine, University of Cadiz, Cadiz, Spain.; Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz (INIBICA), Cadiz, Spain.<br /><searchLink fieldCode="AU" term="%22Turch-Anguera+M%22">Turch-Anguera M</searchLink>; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Cell Signaling and Apoptosis Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Departament de Bioquímica i Biologia Molecular i Institut de Neurociències, Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; Centro de Investigación en Red en Enfermedades Neurodegenerativas (CIBERNED - ISCII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Solé+M%22">Solé M</searchLink>; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Cell Signaling and Apoptosis Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Departament de Bioquímica i Biologia Molecular i Institut de Neurociències, Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; Centro de Investigación en Red en Enfermedades Neurodegenerativas (CIBERNED - ISCII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bakker+N%22">Bakker N</searchLink>; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Scullion+S%22">Scullion S</searchLink>; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK.<br /><searchLink fieldCode="AU" term="%22Comella+JX%22">Comella JX</searchLink>; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Cell Signaling and Apoptosis Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.; Departament de Bioquímica i Biologia Molecular i Institut de Neurociències, Universitat Autònoma de Barcelona (UAB), Bellaterra, Spain.; Centro de Investigación en Red en Enfermedades Neurodegenerativas (CIBERNED - ISCII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Klaassen+I%22">Klaassen I</searchLink>; Ocular Angiogenesis Group, Department of Ophthalmology, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Simó+R%22">Simó R</searchLink>; Department of Medicine, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.; Diabetes and Metabolism Research Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron University Hospital, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM-ISCIII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia-Alloza+M%22">Garcia-Alloza M</searchLink>; Division of Physiology, School of Medicine, University of Cadiz, Cadiz, Spain. monica.garcia@uca.es.; Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz (INIBICA), Cadiz, Spain. monica.garcia@uca.es.<br /><searchLink fieldCode="AU" term="%22Tiwari+VK%22">Tiwari VK</searchLink>; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK. tiwari@health.sdu.dk.; Institute of Molecular Medicine, University of Southern Denmark, Odense C, Denmark. tiwari@health.sdu.dk.; Danish Institute for Advanced Study (DIAS), Odense M, Denmark. tiwari@health.sdu.dk.; Department of Clinical Genetics, Odense University Hospital, Odense C, Denmark. tiwari@health.sdu.dk.<br /><searchLink fieldCode="AU" term="%22Stitt+AW%22">Stitt AW</searchLink>; The Wellcome‑Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, Northern Ireland, UK. a.stitt@qub.ac.uk.
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