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Final analysis of the CLL2-GIVe trial: obinutuzumab, ibrutinib, and venetoclax for untreated CLL with del(17p)/TP53mut.

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Title: Final analysis of the CLL2-GIVe trial: obinutuzumab, ibrutinib, and venetoclax for untreated CLL with del(17p)/TP53mut.
Authors: Huber H; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.; Medizinische Klinik III, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany., Tausch E; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany., Schneider C; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany., Edenhofer S; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany., von Tresckow J; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.; Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Robrecht S; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Giza A; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Zhang C; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Fürstenau M; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Dreger P; Department Medicine V, University of Heidelberg, Heidelberg, Germany., Ritgen M; Klinik für Innere Medizin II, Universitätsklinikum Schleswig-Holstein, Kiel, Germany., Illmer T; Group Practice for Hematology and Oncology, Dresden, Germany., Illert AL; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Dürig J; Deptartment of Internal Medicine, St. Josef Krankenhaus Werden, University Medicine Essen, Essen, Germany., Böttcher S; Medizinische Klinik III, Universitätsklinikum Rostock, Rostock, Germany., Niemann CU; Department of Clinical Medicine, Rigshospitalet, Copenhagen, Denmark., Kneba M; Klinik für Innere Medizin II, Universitätsklinikum Schleswig-Holstein, Kiel, Germany., Al-Sawaf O; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Kreuzer KA; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Fink AM; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Fischer K; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Döhner H; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany., Hallek M; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Eichhorst B; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany., Stilgenbauer S; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.
Source: Blood [Blood] 2023 Sep 14; Vol. 142 (11), pp. 961-972.
Publication Type: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Final analysis of the CLL2-GIVe trial: obinutuzumab, ibrutinib, and venetoclax for untreated CLL with del(17p)/TP53mut.
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  Data: <searchLink fieldCode="AU" term="%22Huber+H%22">Huber H</searchLink>; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.; Medizinische Klinik III, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany.<br /><searchLink fieldCode="AU" term="%22Tausch+E%22">Tausch E</searchLink>; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+C%22">Schneider C</searchLink>; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Edenhofer+S%22">Edenhofer S</searchLink>; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22von+Tresckow+J%22">von Tresckow J</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.; Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Robrecht+S%22">Robrecht S</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Giza+A%22">Giza A</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Fürstenau+M%22">Fürstenau M</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Dreger+P%22">Dreger P</searchLink>; Department Medicine V, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ritgen+M%22">Ritgen M</searchLink>; Klinik für Innere Medizin II, Universitätsklinikum Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Illmer+T%22">Illmer T</searchLink>; Group Practice for Hematology and Oncology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Illert+AL%22">Illert AL</searchLink>; Department of Medicine I, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dürig+J%22">Dürig J</searchLink>; Deptartment of Internal Medicine, St. Josef Krankenhaus Werden, University Medicine Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Böttcher+S%22">Böttcher S</searchLink>; Medizinische Klinik III, Universitätsklinikum Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Niemann+CU%22">Niemann CU</searchLink>; Department of Clinical Medicine, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kneba+M%22">Kneba M</searchLink>; Klinik für Innere Medizin II, Universitätsklinikum Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Al-Sawaf+O%22">Al-Sawaf O</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kreuzer+KA%22">Kreuzer KA</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Fink+AM%22">Fink AM</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+K%22">Fischer K</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Döhner+H%22">Döhner H</searchLink>; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Hallek+M%22">Hallek M</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Eichhorst+B%22">Eichhorst B</searchLink>; Department I of Internal Medicine and Center of Integrated Oncology Aachen Cologne Bonn Duesseldorf, University Hospital of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Stilgenbauer+S%22">Stilgenbauer S</searchLink>; Sektion CLL, Klinik für Innere Medizin III, Universitätsklinikum Ulm, Ulm, Germany.
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