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Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.

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Title: Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
Authors: Alteen MG; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; POINT Biopharma, 22 St Clair Avenue E Suite 1201, Toronto, ON M4T 2S3, Canada., Deme JC; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Alvarez CP; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; SCIEX, 71 Four Valley Dr, Vaughan, ON L4K 4V8, Canada., Loppnau P; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Hutchinson A; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Seitova A; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Chandrasekaran R; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Silva Ramos E; Neuroproteomics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125 Berlin, Germany., Secker C; Neuroproteomics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125 Berlin, Germany., Alqazzaz M; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Wanker EE; Neuroproteomics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125 Berlin, Germany., Lea SM; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA., Arrowsmith CH; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada. Electronic address: cheryl.arrowsmith@uhnresearch.ca., Harding RJ; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: rachel.harding@utoronto.ca.
Source: Structure (London, England : 1993) [Structure] 2023 Sep 07; Vol. 31 (9), pp. 1121-1131.e6. Date of Electronic Publication: 2023 Jun 29.
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40.
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  Data: <searchLink fieldCode="AU" term="%22Alteen+MG%22">Alteen MG</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; POINT Biopharma, 22 St Clair Avenue E Suite 1201, Toronto, ON M4T 2S3, Canada.<br /><searchLink fieldCode="AU" term="%22Deme+JC%22">Deme JC</searchLink>; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.<br /><searchLink fieldCode="AU" term="%22Alvarez+CP%22">Alvarez CP</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; SCIEX, 71 Four Valley Dr, Vaughan, ON L4K 4V8, Canada.<br /><searchLink fieldCode="AU" term="%22Loppnau+P%22">Loppnau P</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Hutchinson+A%22">Hutchinson A</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Seitova+A%22">Seitova A</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Chandrasekaran+R%22">Chandrasekaran R</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Silva+Ramos+E%22">Silva Ramos E</searchLink>; Neuroproteomics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Secker+C%22">Secker C</searchLink>; Neuroproteomics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Alqazzaz+M%22">Alqazzaz M</searchLink>; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Wanker+EE%22">Wanker EE</searchLink>; Neuroproteomics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, 13125 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Lea+SM%22">Lea SM</searchLink>; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.<br /><searchLink fieldCode="AU" term="%22Arrowsmith+CH%22">Arrowsmith CH</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre and Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada. Electronic address: cheryl.arrowsmith@uhnresearch.ca.<br /><searchLink fieldCode="AU" term="%22Harding+RJ%22">Harding RJ</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: rachel.harding@utoronto.ca.
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