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Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity.

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Title: Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity.
Authors: Flaherty SE 3rd; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Bezy O; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Zheng W; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Yan D; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Li X; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Jagarlapudi S; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Albuquerque B; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Esquejo RM; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Peloquin M; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Semache M; Domain Therapeutics North America, Montréal, QC, Canada., Mancini A; Domain Therapeutics North America, Montréal, QC, Canada., Kang L; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Drujan D; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Breitkopf SB; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Griffin JD; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Jean Beltran PM; Machine Learning and Computational Sciences, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Xue L; Machine Learning and Computational Sciences, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Stansfield J; Biostatistics, Early Clinical Development, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Pashos E; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Shakey Q; Biomedicine design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Pehmøller C; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Monetti M; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Birnbaum MJ; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Fortin JP; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA., Wu Z; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA. Zhidan.wu@pfizer.com.
Source: Nature communications [Nat Commun] 2023 Jul 04; Vol. 14 (1), pp. 3953. Date of Electronic Publication: 2023 Jul 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Flaherty+SE+3rd%22">Flaherty SE 3rd</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bezy+O%22">Bezy O</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+W%22">Zheng W</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yan+D%22">Yan D</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jagarlapudi+S%22">Jagarlapudi S</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Albuquerque+B%22">Albuquerque B</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Esquejo+RM%22">Esquejo RM</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Peloquin+M%22">Peloquin M</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Semache+M%22">Semache M</searchLink>; Domain Therapeutics North America, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Mancini+A%22">Mancini A</searchLink>; Domain Therapeutics North America, Montréal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Kang+L%22">Kang L</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Drujan+D%22">Drujan D</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Breitkopf+SB%22">Breitkopf SB</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Griffin+JD%22">Griffin JD</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jean+Beltran+PM%22">Jean Beltran PM</searchLink>; Machine Learning and Computational Sciences, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xue+L%22">Xue L</searchLink>; Machine Learning and Computational Sciences, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Stansfield+J%22">Stansfield J</searchLink>; Biostatistics, Early Clinical Development, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pashos+E%22">Pashos E</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shakey+Q%22">Shakey Q</searchLink>; Biomedicine design, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pehmøller+C%22">Pehmøller C</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Monetti+M%22">Monetti M</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Birnbaum+MJ%22">Birnbaum MJ</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fortin+JP%22">Fortin JP</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+Z%22">Wu Z</searchLink>; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA. Zhidan.wu@pfizer.com.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Jul 04; Vol. 14 (1), pp. 3953. <i>Date of Electronic Publication: </i>2023 Jul 04.
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