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Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease.

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Title: Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease.
Authors: Singh Y; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. yogesh.singh@med.uni-tuebingen.de.; NGS Competence Centre Tübingen (NCCT), University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. yogesh.singh@med.uni-tuebingen.de.; Research Institute of Women's Health, University of Tübingen, Calwerstaße 7/6, 72076, Tübingen, Germany. yogesh.singh@med.uni-tuebingen.de., Trautwein C; Werner Siemens Imaging Centre (WSIC), Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, Röntgenweg 13, 72076, Tübingen, Germany., Romani J; School of Life Sciences, Institute of Bioengineering, Laboratory of Molecular and Chemical Biology of Neurodegeneration, École Polytechnique Fédérale de Lausanne (EPFL), SV LMNN Station 19, 1015 CH, Lausanne, Switzerland., Salker MS; Research Institute of Women's Health, University of Tübingen, Calwerstaße 7/6, 72076, Tübingen, Germany., Neckel PH; Institute of Clinical Anatomy and Cell Analysis, University of Tübingen, Österbergstraße 3, 72074, Tübingen, Germany., Fraccaroli I; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany., Abeditashi M; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany., Woerner N; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany., Admard J; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany., Dhariwal A; Institute of Oral Biology, University of Oslo, Sognsvannsveien 10, 0316, Oslo, Norway., Dueholm MKD; Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, 9220, Aalborg, Denmark., Schäfer KH; Enteric Nervous System Working Group, University of Applied Sciences Kaiserslautern, Zweibrücken Campus, Amerikastrasse 1, 66482, Zweibrücken, Germany., Lang F; Institute of Vegetative Physiology, University of Tübingen, Wilhelmstaße 56, 72074, Tübingen, Germany., Otzen DE; Interdisciplinary Naonscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark., Lashuel HA; School of Life Sciences, Institute of Bioengineering, Laboratory of Molecular and Chemical Biology of Neurodegeneration, École Polytechnique Fédérale de Lausanne (EPFL), SV LMNN Station 19, 1015 CH, Lausanne, Switzerland., Riess O; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. olaf.riess@med.uni-tuebingen.de.; NGS Competence Centre Tübingen (NCCT), University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. olaf.riess@med.uni-tuebingen.de., Casadei N; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. nicolas.casadei@med.uni-tuebingen.de.; NGS Competence Centre Tübingen (NCCT), University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. nicolas.casadei@med.uni-tuebingen.de.
Source: Molecular neurodegeneration [Mol Neurodegener] 2023 Jul 04; Vol. 18 (1), pp. 44. Date of Electronic Publication: 2023 Jul 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease.
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  Data: <searchLink fieldCode="AU" term="%22Singh+Y%22">Singh Y</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. yogesh.singh@med.uni-tuebingen.de.; NGS Competence Centre Tübingen (NCCT), University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. yogesh.singh@med.uni-tuebingen.de.; Research Institute of Women's Health, University of Tübingen, Calwerstaße 7/6, 72076, Tübingen, Germany. yogesh.singh@med.uni-tuebingen.de.<br /><searchLink fieldCode="AU" term="%22Trautwein+C%22">Trautwein C</searchLink>; Werner Siemens Imaging Centre (WSIC), Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, Röntgenweg 13, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Romani+J%22">Romani J</searchLink>; School of Life Sciences, Institute of Bioengineering, Laboratory of Molecular and Chemical Biology of Neurodegeneration, École Polytechnique Fédérale de Lausanne (EPFL), SV LMNN Station 19, 1015 CH, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Salker+MS%22">Salker MS</searchLink>; Research Institute of Women's Health, University of Tübingen, Calwerstaße 7/6, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Neckel+PH%22">Neckel PH</searchLink>; Institute of Clinical Anatomy and Cell Analysis, University of Tübingen, Österbergstraße 3, 72074, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Fraccaroli+I%22">Fraccaroli I</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Abeditashi+M%22">Abeditashi M</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Woerner+N%22">Woerner N</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Admard+J%22">Admard J</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Dhariwal+A%22">Dhariwal A</searchLink>; Institute of Oral Biology, University of Oslo, Sognsvannsveien 10, 0316, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dueholm+MKD%22">Dueholm MKD</searchLink>; Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, 9220, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Schäfer+KH%22">Schäfer KH</searchLink>; Enteric Nervous System Working Group, University of Applied Sciences Kaiserslautern, Zweibrücken Campus, Amerikastrasse 1, 66482, Zweibrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Lang+F%22">Lang F</searchLink>; Institute of Vegetative Physiology, University of Tübingen, Wilhelmstaße 56, 72074, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Otzen+DE%22">Otzen DE</searchLink>; Interdisciplinary Naonscience Center (iNANO), Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus C, Denmark.<br /><searchLink fieldCode="AU" term="%22Lashuel+HA%22">Lashuel HA</searchLink>; School of Life Sciences, Institute of Bioengineering, Laboratory of Molecular and Chemical Biology of Neurodegeneration, École Polytechnique Fédérale de Lausanne (EPFL), SV LMNN Station 19, 1015 CH, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Riess+O%22">Riess O</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. olaf.riess@med.uni-tuebingen.de.; NGS Competence Centre Tübingen (NCCT), University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. olaf.riess@med.uni-tuebingen.de.<br /><searchLink fieldCode="AU" term="%22Casadei+N%22">Casadei N</searchLink>; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. nicolas.casadei@med.uni-tuebingen.de.; NGS Competence Centre Tübingen (NCCT), University of Tübingen, Calwerstaße 7, 72076, Tübingen, Germany. nicolas.casadei@med.uni-tuebingen.de.
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