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Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses.

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Title: Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses.
Authors: Muir R; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America., Metcalf T; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America., Fourati S; PATRU, School of Medicine, Emory University, Atlanta, Georgia, United States of America., Bartsch Y; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America., Kyosiimire-Lugemwa J; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Canderan G; Department of Medicine, Allergy and Immunology, University of Virginia, Charlottesville, Virginia, United States of America., Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America., Muyanja E; PATRU, School of Medicine, Emory University, Atlanta, Georgia, United States of America.; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Okech B; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Namatovu T; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Namara I; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Namuniina A; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Ssetaala A; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Mpendo J; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Nanvubya A; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Kitandwe PK; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Bagaya BS; Department of Immunology and Molecular Biology, School of Biomedical Sciences, Makerere University, College of Health Sciences, Kampala, Uganda., Kiwanuka N; Department of Epidemiology and Biostatistics, School of Public Health, Makerere University, College of Health Sciences, Kampala, Uganda., Nassuna J; Department of Epidemiology and Biostatistics, School of Public Health, Makerere University, College of Health Sciences, Kampala, Uganda., Biribawa VM; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda., Elliott AM; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom., de Dood CJ; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands., Senyonga W; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Balungi P; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Kaleebu P; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Mayanja Y; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Odongo M; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Connors J; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America., Fast P; International AIDS Vaccine Initiative, New York, New York, United States of America.; Pediatric Infectious Diseases, Stanford University School of Medicine, Palo Alto, California, United States of America., Price MA; International AIDS Vaccine Initiative, New York, New York, United States of America.; Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, California, United States of America., Corstjens PLAM; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands., van Dam GJ; Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands., Kamali A; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.; International AIDS Vaccine Initiative, New York, New York, United States of America.; IAVI, New York, New York, United States of America, and Nairobi, Kenya., Sekaly RP; PATRU, School of Medicine, Emory University, Atlanta, Georgia, United States of America., Haddad EK; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.
Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2023 Jul 05; Vol. 17 (7), pp. e0011089. Date of Electronic Publication: 2023 Jul 05 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses.
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  Data: <searchLink fieldCode="AU" term="%22Muir+R%22">Muir R</searchLink>; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Metcalf+T%22">Metcalf T</searchLink>; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Fourati+S%22">Fourati S</searchLink>; PATRU, School of Medicine, Emory University, Atlanta, Georgia, United States of America.<br /><searchLink fieldCode="AU" term="%22Bartsch+Y%22">Bartsch Y</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Kyosiimire-Lugemwa+J%22">Kyosiimire-Lugemwa J</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Canderan+G%22">Canderan G</searchLink>; Department of Medicine, Allergy and Immunology, University of Virginia, Charlottesville, Virginia, United States of America.<br /><searchLink fieldCode="AU" term="%22Alter+G%22">Alter G</searchLink>; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Muyanja+E%22">Muyanja E</searchLink>; PATRU, School of Medicine, Emory University, Atlanta, Georgia, United States of America.; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Okech+B%22">Okech B</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Namatovu+T%22">Namatovu T</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Namara+I%22">Namara I</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Namuniina+A%22">Namuniina A</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Ssetaala+A%22">Ssetaala A</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Mpendo+J%22">Mpendo J</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Nanvubya+A%22">Nanvubya A</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Kitandwe+PK%22">Kitandwe PK</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Bagaya+BS%22">Bagaya BS</searchLink>; Department of Immunology and Molecular Biology, School of Biomedical Sciences, Makerere University, College of Health Sciences, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kiwanuka+N%22">Kiwanuka N</searchLink>; Department of Epidemiology and Biostatistics, School of Public Health, Makerere University, College of Health Sciences, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Nassuna+J%22">Nassuna J</searchLink>; Department of Epidemiology and Biostatistics, School of Public Health, Makerere University, College of Health Sciences, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Biribawa+VM%22">Biribawa VM</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Elliott+AM%22">Elliott AM</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22de+Dood+CJ%22">de Dood CJ</searchLink>; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Senyonga+W%22">Senyonga W</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Balungi+P%22">Balungi P</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Kaleebu+P%22">Kaleebu P</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Mayanja+Y%22">Mayanja Y</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Odongo+M%22">Odongo M</searchLink>; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.<br /><searchLink fieldCode="AU" term="%22Connors+J%22">Connors J</searchLink>; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Fast+P%22">Fast P</searchLink>; International AIDS Vaccine Initiative, New York, New York, United States of America.; Pediatric Infectious Diseases, Stanford University School of Medicine, Palo Alto, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Price+MA%22">Price MA</searchLink>; International AIDS Vaccine Initiative, New York, New York, United States of America.; Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Corstjens+PLAM%22">Corstjens PLAM</searchLink>; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Dam+GJ%22">van Dam GJ</searchLink>; Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kamali+A%22">Kamali A</searchLink>; UVRI-IAVI HIV Vaccine Program, Entebbe, Uganda.; International AIDS Vaccine Initiative, New York, New York, United States of America.; IAVI, New York, New York, United States of America, and Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Sekaly+RP%22">Sekaly RP</searchLink>; PATRU, School of Medicine, Emory University, Atlanta, Georgia, United States of America.<br /><searchLink fieldCode="AU" term="%22Haddad+EK%22">Haddad EK</searchLink>; Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.
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