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LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment.

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Title: LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment.
Authors: Zhang N; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China; BRL Medicine, Inc, Shanghai 201109, China., Liu X; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China., Qin J; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China., Sun Y; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China., Xiong H; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China., Lin B; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China., Liu K; BRL Medicine, Inc, Shanghai 201109, China., Tan B; BRL Medicine, Inc, Shanghai 201109, China., Zhang C; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, China., Huang C; Department of Gastrointestinal Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou 350001, China., Ren S; Department of Urology, Shanghai Changzheng Hospital, Shanghai 200003, China. Electronic address: renshancheng@gmail.com., Liu M; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address: myliu@bio.ecnu.edu.cn., Du B; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address: bdu@bio.ecnu.edu.cn.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2023 Sep 06; Vol. 31 (9), pp. 2575-2590. Date of Electronic Publication: 2023 Jul 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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An: 37408308
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PubType: Academic Journal
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  Data: LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+N%22">Zhang N</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China; BRL Medicine, Inc, Shanghai 201109, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China.<br /><searchLink fieldCode="AU" term="%22Qin+J%22">Qin J</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China.<br /><searchLink fieldCode="AU" term="%22Xiong+H%22">Xiong H</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China.<br /><searchLink fieldCode="AU" term="%22Lin+B%22">Lin B</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China.<br /><searchLink fieldCode="AU" term="%22Liu+K%22">Liu K</searchLink>; BRL Medicine, Inc, Shanghai 201109, China.<br /><searchLink fieldCode="AU" term="%22Tan+B%22">Tan B</searchLink>; BRL Medicine, Inc, Shanghai 201109, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Orthopedics, Shanghai Changzheng Hospital, Shanghai 200003, China.<br /><searchLink fieldCode="AU" term="%22Huang+C%22">Huang C</searchLink>; Department of Gastrointestinal Surgery, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou 350001, China.<br /><searchLink fieldCode="AU" term="%22Ren+S%22">Ren S</searchLink>; Department of Urology, Shanghai Changzheng Hospital, Shanghai 200003, China. Electronic address: renshancheng@gmail.com.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address: myliu@bio.ecnu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Du+B%22">Du B</searchLink>; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address: bdu@bio.ecnu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2023 Sep 06; Vol. 31 (9), pp. 2575-2590. <i>Date of Electronic Publication: </i>2023 Jul 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ymthe.2023.06.015
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      – Code: eng
        Text: English
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            – D: 06
              M: 09
              Text: 2023 Sep 06
              Type: published
              Y: 2023
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