Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors.
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| Title: | Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors. |
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| Authors: | Glockzin K; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Meneely KM; Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States., Hughes R; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Maatouk SW; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Piña GE; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Suthagar K; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Clinch K; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Buckler JN; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Lamb AL; Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States., Tyler PC; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Meek TD; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Katzfuss A; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States. |
| Source: | Biochemistry [Biochemistry] 2023 Jul 18; Vol. 62 (14), pp. 2182-2201. Date of Electronic Publication: 2023 Jul 07. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37418678 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Glockzin+K%22">Glockzin K</searchLink>; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States.<br /><searchLink fieldCode="AU" term="%22Meneely+KM%22">Meneely KM</searchLink>; Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States.<br /><searchLink fieldCode="AU" term="%22Hughes+R%22">Hughes R</searchLink>; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States.<br /><searchLink fieldCode="AU" term="%22Maatouk+SW%22">Maatouk SW</searchLink>; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States.<br /><searchLink fieldCode="AU" term="%22Piña+GE%22">Piña GE</searchLink>; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States.<br /><searchLink fieldCode="AU" term="%22Suthagar+K%22">Suthagar K</searchLink>; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand.<br /><searchLink fieldCode="AU" term="%22Clinch+K%22">Clinch K</searchLink>; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand.<br /><searchLink fieldCode="AU" term="%22Buckler+JN%22">Buckler JN</searchLink>; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand.<br /><searchLink fieldCode="AU" term="%22Lamb+AL%22">Lamb AL</searchLink>; Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States.<br /><searchLink fieldCode="AU" term="%22Tyler+PC%22">Tyler PC</searchLink>; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand.<br /><searchLink fieldCode="AU" term="%22Meek+TD%22">Meek TD</searchLink>; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States.<br /><searchLink fieldCode="AU" term="%22Katzfuss+A%22">Katzfuss A</searchLink>; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220370623%22">Biochemistry</searchLink> [Biochemistry] 2023 Jul 18; Vol. 62 (14), pp. 2182-2201. <i>Date of Electronic Publication: </i>2023 Jul 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370623 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200062960%22">00062960 </searchLink><i>NLM ISO Abbreviation: </i>Biochemistry <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37418678 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.biochem.3c00116 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2182 Titles: – TitleFull: Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Glockzin K – PersonEntity: Name: NameFull: Meneely KM – PersonEntity: Name: NameFull: Hughes R – PersonEntity: Name: NameFull: Maatouk SW – PersonEntity: Name: NameFull: Piña GE – PersonEntity: Name: NameFull: Suthagar K – PersonEntity: Name: NameFull: Clinch K – PersonEntity: Name: NameFull: Buckler JN – PersonEntity: Name: NameFull: Lamb AL – PersonEntity: Name: NameFull: Tyler PC – PersonEntity: Name: NameFull: Meek TD – PersonEntity: Name: NameFull: Katzfuss A IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 07 Text: 2023 Jul 18 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1520-4995 Numbering: – Type: volume Value: 62 – Type: issue Value: 14 Titles: – TitleFull: Biochemistry Type: main |
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