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Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition.

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Title: Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition.
Authors: Gao CW; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD., Lin W; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD., Riddle RC; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD.; Research and Development Service, Baltimore Veterans Administration Medical Center, Baltimore, MD., Kushwaha P; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD., Boukas L; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Biostatistics, Johns Hopkins University School of Public Health, Baltimore, MD., Björnsson HT; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.; Landspítali University Hospital, Reykjavík, Iceland., Hansen KD; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Biostatistics, Johns Hopkins University School of Public Health, Baltimore, MD., Fahrner JA; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jun 30. Date of Electronic Publication: 2023 Jun 30.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Gao+CW%22">Gao CW</searchLink>; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Lin+W%22">Lin W</searchLink>; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Riddle+RC%22">Riddle RC</searchLink>; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, MD.; Research and Development Service, Baltimore Veterans Administration Medical Center, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Kushwaha+P%22">Kushwaha P</searchLink>; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Boukas+L%22">Boukas L</searchLink>; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Biostatistics, Johns Hopkins University School of Public Health, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Björnsson+HT%22">Björnsson HT</searchLink>; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.; Faculty of Medicine, University of Iceland, Reykjavík, Iceland.; Landspítali University Hospital, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Hansen+KD%22">Hansen KD</searchLink>; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Biostatistics, Johns Hopkins University School of Public Health, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Fahrner+JA%22">Fahrner JA</searchLink>; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1101/2023.06.23.546270
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        Text: English
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              Text: 2023 Jun 30
              Type: published
              Y: 2023
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