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ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.

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Title: ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
Authors: Mota I; Department of Pathology, Boston Children's Hospital, Boston, MA, USA., Patrucco E; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Mastini C; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Mahadevan NR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA., Thai TC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Bergaggio E; Department of Pathology, Boston Children's Hospital, Boston, MA, USA., Cheong TC; Department of Pathology, Boston Children's Hospital, Boston, MA, USA., Leonardi G; Department of Pathology, Boston Children's Hospital, Boston, MA, USA., Karaca-Atabay E; Department of Pathology, Boston Children's Hospital, Boston, MA, USA., Campisi M; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Poggio T; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Menotti M; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Ambrogio C; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Longo DL; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.; Molecular Imaging Center, University of Torino, Torino, Italy.; Institute of Biostructures and Bioimaging (IBB), National Research Council of Italy (CNR), Torino, Italy., Klaeger S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Keshishian H; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sztupinszki ZM; Danish Cancer Society Research Center, Copenhagen, Denmark.; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA., Szallasi Z; Danish Cancer Society Research Center, Copenhagen, Denmark.; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA.; Department of Bioinformatics, Semmelweis University, Budapest, Hungary., Keskin DB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Computer Science, Metropolitan College, Boston University, Boston, MA, USA.; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark, Lyngby, Denmark., Duke-Cohan JS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA., Reinhold B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA., Carr SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wu CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Moynihan KD; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Irvine DJ; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Barbie DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Reinherz EL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA., Voena C; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Awad MM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Blasco RB; Department of Pathology, Boston Children's Hospital, Boston, MA, USA. rafael.b.blasco@gmail.com., Chiarle R; Department of Pathology, Boston Children's Hospital, Boston, MA, USA. roberto.chiarle@childrens.harvard.edu.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy. roberto.chiarle@childrens.harvard.edu.
Source: Nature cancer [Nat Cancer] 2023 Jul; Vol. 4 (7), pp. 1016-1035. Date of Electronic Publication: 2023 Jul 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Mota+I%22">Mota I</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Patrucco+E%22">Patrucco E</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Mastini+C%22">Mastini C</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Mahadevan+NR%22">Mahadevan NR</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Thai+TC%22">Thai TC</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bergaggio+E%22">Bergaggio E</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cheong+TC%22">Cheong TC</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Leonardi+G%22">Leonardi G</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Karaca-Atabay+E%22">Karaca-Atabay E</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Campisi+M%22">Campisi M</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Poggio+T%22">Poggio T</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Menotti+M%22">Menotti M</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Ambrogio+C%22">Ambrogio C</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Longo+DL%22">Longo DL</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.; Molecular Imaging Center, University of Torino, Torino, Italy.; Institute of Biostructures and Bioimaging (IBB), National Research Council of Italy (CNR), Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Klaeger+S%22">Klaeger S</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Keshishian+H%22">Keshishian H</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sztupinszki+ZM%22">Sztupinszki ZM</searchLink>; Danish Cancer Society Research Center, Copenhagen, Denmark.; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Szallasi+Z%22">Szallasi Z</searchLink>; Danish Cancer Society Research Center, Copenhagen, Denmark.; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA.; Department of Bioinformatics, Semmelweis University, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Keskin+DB%22">Keskin DB</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Translational Immunogenomics Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Computer Science, Metropolitan College, Boston University, Boston, MA, USA.; Section for Bioinformatics, Department of Health Technology, Technical University of Denmark, Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Duke-Cohan+JS%22">Duke-Cohan JS</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Reinhold+B%22">Reinhold B</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Carr+SA%22">Carr SA</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+CJ%22">Wu CJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Moynihan+KD%22">Moynihan KD</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Irvine+DJ%22">Irvine DJ</searchLink>; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.<br /><searchLink fieldCode="AU" term="%22Barbie+DA%22">Barbie DA</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Reinherz+EL%22">Reinherz EL</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Voena+C%22">Voena C</searchLink>; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Awad+MM%22">Awad MM</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Blasco+RB%22">Blasco RB</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA. rafael.b.blasco@gmail.com.<br /><searchLink fieldCode="AU" term="%22Chiarle+R%22">Chiarle R</searchLink>; Department of Pathology, Boston Children's Hospital, Boston, MA, USA. roberto.chiarle@childrens.harvard.edu.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy. roberto.chiarle@childrens.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2023 Jul; Vol. 4 (7), pp. 1016-1035. <i>Date of Electronic Publication: </i>2023 Jul 10.
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