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A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis.

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Title: A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis.
Authors: Mascarenhas J; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Migliaccio AR; Altius Institute for Biomedical Sciences, Seattle, Washington., Kosiorek H; Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona., Bhave R; Comprehensive Cancer Center of Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina., Palmer J; Mayo Clinic Scottsdale, Arizona., Kuykendall A; Department of Hematologic Malignancy, Moffitt Cancer Center, Tampa, Florida., Mesa R; Comprehensive Cancer Center of Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina., Rampal RK; Leukemia Service, Department of Medicine, Center for Hematologic Malignancies, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York., Gerds AT; Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio., Yacoub A; The University of Kansas Cancer Center, Westwood, Kansas., Pettit K; University of Michigan, Comprehensive Cancer Center, Ann Arbor, Michigan., Talpaz M; University of Michigan, Comprehensive Cancer Center, Ann Arbor, Michigan., Komrokji R; Department of Hematologic Malignancy, Moffitt Cancer Center, Tampa, Florida., Kremyanskaya M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Gonzalez A; The University of Texas Health Science Center at San Antonio, San Antonio, Texas., Fabris F; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Johnson K; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Dougherty M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., McGovern E; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York., Arango Ossa J; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York., Domenico D; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York., Farnoud N; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York., Weinberg RS; New York Blood Center, New York, New York., Kong A; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Najfeld V; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Vannucchi AM; University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy., Arciprete F; Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy., Zingariello M; Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy., Falchi M; National HIV/AIDS Research Center, Istituto Superiore di Sanità, Viale Regina Elena Rome Italy., Salama ME; Sonic Healthcare, Austin, Texas., Mead-Harvey C; Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona., Dueck A; Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona., Varricchio L; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Hoffman R; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Sep 15; Vol. 29 (18), pp. 3622-3632.
Publication Type: Clinical Trial, Phase I; Multicenter Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Phase Ib Trial of AVID200, a TGFβ 1/3 Trap, in Patients with Myelofibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Mascarenhas+J%22">Mascarenhas J</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Migliaccio+AR%22">Migliaccio AR</searchLink>; Altius Institute for Biomedical Sciences, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Kosiorek+H%22">Kosiorek H</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Bhave+R%22">Bhave R</searchLink>; Comprehensive Cancer Center of Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Palmer+J%22">Palmer J</searchLink>; Mayo Clinic Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Kuykendall+A%22">Kuykendall A</searchLink>; Department of Hematologic Malignancy, Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Mesa+R%22">Mesa R</searchLink>; Comprehensive Cancer Center of Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Rampal+RK%22">Rampal RK</searchLink>; Leukemia Service, Department of Medicine, Center for Hematologic Malignancies, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Gerds+AT%22">Gerds AT</searchLink>; Cleveland Clinic Taussig Cancer Institute, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Yacoub+A%22">Yacoub A</searchLink>; The University of Kansas Cancer Center, Westwood, Kansas.<br /><searchLink fieldCode="AU" term="%22Pettit+K%22">Pettit K</searchLink>; University of Michigan, Comprehensive Cancer Center, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Talpaz+M%22">Talpaz M</searchLink>; University of Michigan, Comprehensive Cancer Center, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Komrokji+R%22">Komrokji R</searchLink>; Department of Hematologic Malignancy, Moffitt Cancer Center, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Kremyanskaya+M%22">Kremyanskaya M</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Gonzalez+A%22">Gonzalez A</searchLink>; The University of Texas Health Science Center at San Antonio, San Antonio, Texas.<br /><searchLink fieldCode="AU" term="%22Fabris+F%22">Fabris F</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Johnson+K%22">Johnson K</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Dougherty+M%22">Dougherty M</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22McGovern+E%22">McGovern E</searchLink>; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Arango+Ossa+J%22">Arango Ossa J</searchLink>; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Domenico+D%22">Domenico D</searchLink>; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Farnoud+N%22">Farnoud N</searchLink>; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Weinberg+RS%22">Weinberg RS</searchLink>; New York Blood Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Kong+A%22">Kong A</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Najfeld+V%22">Najfeld V</searchLink>; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Vannucchi+AM%22">Vannucchi AM</searchLink>; University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Arciprete+F%22">Arciprete F</searchLink>; Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Zingariello+M%22">Zingariello M</searchLink>; Unit of Microscopic and Ultrastructural Anatomy, University Campus Bio-Medico, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Falchi+M%22">Falchi M</searchLink>; National HIV/AIDS Research Center, Istituto Superiore di Sanità, Viale Regina Elena Rome Italy.<br /><searchLink fieldCode="AU" term="%22Salama+ME%22">Salama ME</searchLink>; Sonic Healthcare, Austin, Texas.<br /><searchLink fieldCode="AU" term="%22Mead-Harvey+C%22">Mead-Harvey C</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Dueck+A%22">Dueck A</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona.<br /><searchLink fieldCode="AU" term="%22Varricchio+L%22">Varricchio L</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Hoffman+R%22">Hoffman R</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2023 Sep 15; Vol. 29 (18), pp. 3622-3632.
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  Data: Clinical Trial, Phase I; Multicenter Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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