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CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease.

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Title: CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease.
Authors: Horie K; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Eisai Inc., Nutley, NJ, USA., Salvadó G; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Barthélemy NR; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Janelidze S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Li Y; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., He Y; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Saef B; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Chen CD; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA., Jiang H; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Strandberg O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Pichet Binette A; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden., Palmqvist S; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Sato C; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA., Sachdev P; Eisai Inc., Nutley, NJ, USA., Koyama A; Eisai Inc., Nutley, NJ, USA., Gordon BA; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA., Benzinger TLS; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Holtzman DM; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA., Mattsson-Carlgren N; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden., Stomrud E; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Ossenkoppele R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se., Bateman RJ; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA. batemanr@wustl.edu.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.
Source: Nature medicine [Nat Med] 2023 Aug; Vol. 29 (8), pp. 1954-1963. Date of Electronic Publication: 2023 Jul 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Horie+K%22">Horie K</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Eisai Inc., Nutley, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Salvadó+G%22">Salvadó G</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Barthélemy+NR%22">Barthélemy NR</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Janelidze+S%22">Janelidze S</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Saef+B%22">Saef B</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Chen+CD%22">Chen CD</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Strandberg+O%22">Strandberg O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Pichet+Binette+A%22">Pichet Binette A</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Palmqvist+S%22">Palmqvist S</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Sato+C%22">Sato C</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Sachdev+P%22">Sachdev P</searchLink>; Eisai Inc., Nutley, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Koyama+A%22">Koyama A</searchLink>; Eisai Inc., Nutley, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+BA%22">Gordon BA</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Benzinger+TLS%22">Benzinger TLS</searchLink>; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Mattsson-Carlgren+N%22">Mattsson-Carlgren N</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Stomrud+E%22">Stomrud E</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Ossenkoppele+R%22">Ossenkoppele R</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schindler+SE%22">Schindler SE</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden. oskar.hansson@med.lu.se.; Memory Clinic, Skåne University Hospital, Malmö, Sweden. oskar.hansson@med.lu.se.<br /><searchLink fieldCode="AU" term="%22Bateman+RJ%22">Bateman RJ</searchLink>; The Tracy Family SILQ Center, Washington University School of Medicine, St Louis, MO, USA. batemanr@wustl.edu.; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. batemanr@wustl.edu.
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  Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2023 Aug; Vol. 29 (8), pp. 1954-1963. <i>Date of Electronic Publication: </i>2023 Jul 13.
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