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Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis.

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Title: Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis.
Authors: Thompson RJ; Institute of Liver Studies, King's College London, London, UK., Artan R; Department of Pediatric Gastroenterology, Akdeniz University, Antalya, Turkey., Baumann U; Pediatric Gastroenterology and Hepatology, Hannover Medical School, Hannover, Germany., Calvo PL; Pediatric Gastroenterology Unit, Regina Margherita Children's Hospital, Azienda Ospedaliera-Città della Salute e della Scienza di Torino, Turin, Italy., Czubkowski P; Department of Gastroenterology, Hepatology, Nutritional Disorders, and Pediatrics, The Children's Memorial Health Institute, Warsaw, Poland., Dalgic B; Department of Pediatric Gastroenterology, Gazi University Faculty of Medicine, Ankara, Turkey., D'Antiga L; Pediatric Hepatology, Gastroenterology, and Transplantation, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Di Giorgio A; Pediatric Hepatology, Gastroenterology, and Transplantation, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Durmaz Ö; Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey., Gonzalès E; Hépatologie et Transplantation Hépatique Pédiatriques, Centre de Référence de l'Atrésie des Voies Biliaires et des Cholestases Génétiques, FSMR FILFOIE, ERN RARE LIVER, Hôpital Bicêtre, AP-HP, Université Paris-Saclay, Hépatinov, Inserm U 1193, Paris, France., Grammatikopoulos T; Institute of Liver Studies, King's College London, London, UK.; Pediatric Liver, GI, and Nutrition Center and MowatLabs, King's College Hospital NHS Trust, London, UK., Gupte G; Liver Unit and Small Bowel Transplantation, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK., Hardikar W; Department of Gastroenterology, Royal Children's Hospital, Melbourne, Australia., Houwen RHJ; Department of Pediatric Gastroenterology at the Wilhelmina Children's Hospital and University Medical Center, Utrecht, The Netherlands., Kamath BM; Division of Gastroenterology, Hepatology, and Nutrition, Hospital for Sick Children and the University of Toronto, Toronto, ON, Canada., Karpen SJ; Pediatrics Department, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA, USA., Lacaille F; Pediatric Gastroenterology-Hepatology-Nutrition Unit, Hôpital Universitaire Necker-Enfants Malades, Paris, France., Lachaux A; Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Service D'hépatogastoentérologie et Nutrition Pédiatrique, Lyon, France., Lainka E; Department of Pediatric Gastroenterology, Hepatology, and Liver Transplantation, University Children's Hospital, Essen, Germany., Loomes KM; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Mack CL; Pediatric Gastroenterology, Hepatology, & Nutrition, Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI, USA., Mattsson JP; Albireo Pharma, Inc., Boston, MA, USA., McKiernan P; Liver Unit and Small Bowel Transplantation, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK., Ni Q; Albireo Pharma, Inc., Boston, MA, USA., Özen H; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Hacettepe University Faculty of Medicine, Ankara, Turkey., Rajwal SR; Children's Liver Unit, Leeds Teaching Hospitals NHS Trust, Leeds Children's Hospital, Leeds, UK., Roquelaure B; CHU, Hospital de la Timone, Marseille, France., Shteyer E; Faculty of Medicine, Hebrew University of Jerusalem, Juliet Keidan Department of Pediatric Gastroenterology, Shaare Zedek Medical Center, Jerusalem, Israel., Sokal E; Université Catholique de Louvain, Cliniques St Luc, Brussels, Belgium., Sokol RJ; University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, CO, USA., Soufi N; Pediatrics Department, Children's Hospital Los Angeles, Los Angeles, CA, USA., Sturm E; Pediatric Gastroenterology and Hepatology, University Children's Hospital Tübingen, Tübingen, Germany., Tessier ME; Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA., van der Woerd WL; Department of Pediatric Gastroenterology at the Wilhelmina Children's Hospital and University Medical Center, Utrecht, The Netherlands., Verkade HJ; Department of Pediatrics, University of Groningen, Beatrix Children's Hospital/University Medical Center Groningen, Groningen, The Netherlands., Vittorio JM; Department of Surgery, Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY, USA., Wallefors T; Albireo Pharma, Inc., Boston, MA, USA., Warholic N; Albireo Pharma, Inc., Boston, MA, USA., Yu Q; Albireo Pharma, Inc., Boston, MA, USA., Horn P; Albireo Pharma, Inc., Boston, MA, USA., Kjems L; Albireo Pharma, Inc., Boston, MA, USA.
Source: JHEP reports : innovation in hepatology [JHEP Rep] 2023 Apr 29; Vol. 5 (8), pp. 100782. Date of Electronic Publication: 2023 Apr 29 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis.
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  Data: <searchLink fieldCode="AU" term="%22Thompson+RJ%22">Thompson RJ</searchLink>; Institute of Liver Studies, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Artan+R%22">Artan R</searchLink>; Department of Pediatric Gastroenterology, Akdeniz University, Antalya, Turkey.<br /><searchLink fieldCode="AU" term="%22Baumann+U%22">Baumann U</searchLink>; Pediatric Gastroenterology and Hepatology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Calvo+PL%22">Calvo PL</searchLink>; Pediatric Gastroenterology Unit, Regina Margherita Children's Hospital, Azienda Ospedaliera-Città della Salute e della Scienza di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Czubkowski+P%22">Czubkowski P</searchLink>; Department of Gastroenterology, Hepatology, Nutritional Disorders, and Pediatrics, The Children's Memorial Health Institute, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Dalgic+B%22">Dalgic B</searchLink>; Department of Pediatric Gastroenterology, Gazi University Faculty of Medicine, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22D'Antiga+L%22">D'Antiga L</searchLink>; Pediatric Hepatology, Gastroenterology, and Transplantation, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Giorgio+A%22">Di Giorgio A</searchLink>; Pediatric Hepatology, Gastroenterology, and Transplantation, Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Durmaz+Ö%22">Durmaz Ö</searchLink>; Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Gonzalès+E%22">Gonzalès E</searchLink>; Hépatologie et Transplantation Hépatique Pédiatriques, Centre de Référence de l'Atrésie des Voies Biliaires et des Cholestases Génétiques, FSMR FILFOIE, ERN RARE LIVER, Hôpital Bicêtre, AP-HP, Université Paris-Saclay, Hépatinov, Inserm U 1193, Paris, France.<br /><searchLink fieldCode="AU" term="%22Grammatikopoulos+T%22">Grammatikopoulos T</searchLink>; Institute of Liver Studies, King's College London, London, UK.; Pediatric Liver, GI, and Nutrition Center and MowatLabs, King's College Hospital NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Gupte+G%22">Gupte G</searchLink>; Liver Unit and Small Bowel Transplantation, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Hardikar+W%22">Hardikar W</searchLink>; Department of Gastroenterology, Royal Children's Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Houwen+RHJ%22">Houwen RHJ</searchLink>; Department of Pediatric Gastroenterology at the Wilhelmina Children's Hospital and University Medical Center, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kamath+BM%22">Kamath BM</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Hospital for Sick Children and the University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Karpen+SJ%22">Karpen SJ</searchLink>; Pediatrics Department, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Lacaille+F%22">Lacaille F</searchLink>; Pediatric Gastroenterology-Hepatology-Nutrition Unit, Hôpital Universitaire Necker-Enfants Malades, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lachaux+A%22">Lachaux A</searchLink>; Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, Service D'hépatogastoentérologie et Nutrition Pédiatrique, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Lainka+E%22">Lainka E</searchLink>; Department of Pediatric Gastroenterology, Hepatology, and Liver Transplantation, University Children's Hospital, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Loomes+KM%22">Loomes KM</searchLink>; Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mack+CL%22">Mack CL</searchLink>; Pediatric Gastroenterology, Hepatology, & Nutrition, Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI, USA.<br /><searchLink fieldCode="AU" term="%22Mattsson+JP%22">Mattsson JP</searchLink>; Albireo Pharma, Inc., Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McKiernan+P%22">McKiernan P</searchLink>; Liver Unit and Small Bowel Transplantation, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Ni+Q%22">Ni Q</searchLink>; Albireo Pharma, Inc., Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Özen+H%22">Özen H</searchLink>; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Hacettepe University Faculty of Medicine, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Rajwal+SR%22">Rajwal SR</searchLink>; Children's Liver Unit, Leeds Teaching Hospitals NHS Trust, Leeds Children's Hospital, Leeds, UK.<br /><searchLink fieldCode="AU" term="%22Roquelaure+B%22">Roquelaure B</searchLink>; CHU, Hospital de la Timone, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Shteyer+E%22">Shteyer E</searchLink>; Faculty of Medicine, Hebrew University of Jerusalem, Juliet Keidan Department of Pediatric Gastroenterology, Shaare Zedek Medical Center, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Sokal+E%22">Sokal E</searchLink>; Université Catholique de Louvain, Cliniques St Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Sokol+RJ%22">Sokol RJ</searchLink>; University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Soufi+N%22">Soufi N</searchLink>; Pediatrics Department, Children's Hospital Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sturm+E%22">Sturm E</searchLink>; Pediatric Gastroenterology and Hepatology, University Children's Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Tessier+ME%22">Tessier ME</searchLink>; Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22van+der+Woerd+WL%22">van der Woerd WL</searchLink>; Department of Pediatric Gastroenterology at the Wilhelmina Children's Hospital and University Medical Center, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verkade+HJ%22">Verkade HJ</searchLink>; Department of Pediatrics, University of Groningen, Beatrix Children's Hospital/University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vittorio+JM%22">Vittorio JM</searchLink>; Department of Surgery, Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wallefors+T%22">Wallefors T</searchLink>; Albireo Pharma, Inc., Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Warholic+N%22">Warholic N</searchLink>; Albireo Pharma, Inc., Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+Q%22">Yu Q</searchLink>; Albireo Pharma, Inc., Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Horn+P%22">Horn P</searchLink>; Albireo Pharma, Inc., Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kjems+L%22">Kjems L</searchLink>; Albireo Pharma, Inc., Boston, MA, USA.
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