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Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.

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Title: Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.
Authors: Sturgess K; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Yankova E; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK.; Milner Therapeutics Institute, University of Cambridge, Puddicombe Way, Cambridge, CB2 0AW, UK., Vijayabaskar MS; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Isobe T; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Rak J; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Kucinski I; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Barile M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Webster NA; Storm Therapeutics Ltd, Babraham Research Campus, Cambridge, CB22 3AT, UK., Eleftheriou M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK.; Milner Therapeutics Institute, University of Cambridge, Puddicombe Way, Cambridge, CB2 0AW, UK., Hannah R; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Gozdecka M; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Vassiliou G; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Rausch O; Storm Therapeutics Ltd, Babraham Research Campus, Cambridge, CB22 3AT, UK., Wilson NK; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK., Göttgens B; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK. bg200@cam.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK. bg200@cam.ac.uk., Tzelepis K; Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK. kt404@cam.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, CB2 0AW, UK. kt404@cam.ac.uk.; Milner Therapeutics Institute, University of Cambridge, Puddicombe Way, Cambridge, CB2 0AW, UK. kt404@cam.ac.uk.; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK. kt404@cam.ac.uk.
Source: Leukemia [Leukemia] 2023 Oct; Vol. 37 (10), pp. 2133-2137. Date of Electronic Publication: 2023 Jul 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
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