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CSC01 shows promise as a potential inhibitor of the oncogenic G13D mutant of KRAS: an in silico approach.

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Title: CSC01 shows promise as a potential inhibitor of the oncogenic G13D mutant of KRAS: an in silico approach.
Authors: Durojaye OA; MOE Key Laboratory of Membraneless Organelle and Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, 230027, Anhui, China. lanredurojaye@mail.ustc.edu.cn.; School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China. lanredurojaye@mail.ustc.edu.cn.; Department of Chemical Sciences, Coal City University, Emene, EnuguState, Nigeria. lanredurojaye@mail.ustc.edu.cn., Ejaz U; MOE Key Laboratory of Membraneless Organelle and Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, 230027, Anhui, China.; School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China.; School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China., Uzoeto HO; Federal College of Dental Technology, Trans-Ekulu, Enugu State, Nigeria.; Department of Biological Sciences, Coal City University, Emene, Enugu State, Nigeria., Fadahunsi AA; Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, 04469, USA., Opabunmi AO; RNA Medical Center, International Institutes of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang University-University of Edinburgh Institute, Zhejiang University, Hangzhou, China.; The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Ekpo DE; Institute of Biological Science and Technology, National Engineering Research Center for Non-Food Biorefinery, Guangxi Academy of Sciences, Nanning, 530007, China.; Department of Biochemistry, Faculty of Biological Sciences, University of Nigeria, 410001, Nsukka, Enugu State, Nigeria., Sedzro DM; Wisconsin National Primate Research Center, University of Wisconsin Graduate School, 1220 Capitol Court, Madison, 53715, WI, USA. sedzro@wisc.edu., Idris MO; School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China. idrisolaitan2009@gmail.com.
Source: Amino acids [Amino Acids] 2023 Dec; Vol. 55 (12), pp. 1745-1764. Date of Electronic Publication: 2023 Jul 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9200312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1438-2199 (Electronic) Linking ISSN: 09394451 NLM ISO Abbreviation: Amino Acids Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CSC01 shows promise as a potential inhibitor of the oncogenic G13D mutant of KRAS: an in silico approach.
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  Data: <searchLink fieldCode="AU" term="%22Durojaye+OA%22">Durojaye OA</searchLink>; MOE Key Laboratory of Membraneless Organelle and Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, 230027, Anhui, China. lanredurojaye@mail.ustc.edu.cn.; School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China. lanredurojaye@mail.ustc.edu.cn.; Department of Chemical Sciences, Coal City University, Emene, EnuguState, Nigeria. lanredurojaye@mail.ustc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ejaz+U%22">Ejaz U</searchLink>; MOE Key Laboratory of Membraneless Organelle and Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, 230027, Anhui, China.; School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China.; School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009, China.<br /><searchLink fieldCode="AU" term="%22Uzoeto+HO%22">Uzoeto HO</searchLink>; Federal College of Dental Technology, Trans-Ekulu, Enugu State, Nigeria.; Department of Biological Sciences, Coal City University, Emene, Enugu State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Fadahunsi+AA%22">Fadahunsi AA</searchLink>; Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME, 04469, USA.<br /><searchLink fieldCode="AU" term="%22Opabunmi+AO%22">Opabunmi AO</searchLink>; RNA Medical Center, International Institutes of Medicine, Zhejiang University, Hangzhou, China.; Zhejiang University-University of Edinburgh Institute, Zhejiang University, Hangzhou, China.; The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Ekpo+DE%22">Ekpo DE</searchLink>; Institute of Biological Science and Technology, National Engineering Research Center for Non-Food Biorefinery, Guangxi Academy of Sciences, Nanning, 530007, China.; Department of Biochemistry, Faculty of Biological Sciences, University of Nigeria, 410001, Nsukka, Enugu State, Nigeria.<br /><searchLink fieldCode="AU" term="%22Sedzro+DM%22">Sedzro DM</searchLink>; Wisconsin National Primate Research Center, University of Wisconsin Graduate School, 1220 Capitol Court, Madison, 53715, WI, USA. sedzro@wisc.edu.<br /><searchLink fieldCode="AU" term="%22Idris+MO%22">Idris MO</searchLink>; School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China. idrisolaitan2009@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%229200312%22">Amino acids</searchLink> [Amino Acids] 2023 Dec; Vol. 55 (12), pp. 1745-1764. <i>Date of Electronic Publication: </i>2023 Jul 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Austria <i>NLM ID: </i>9200312 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1438-2199 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209394451%22">09394451 </searchLink><i>NLM ISO Abbreviation: </i>Amino Acids <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00726-023-03304-2
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        Text: English
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              M: 12
              Text: 2023 Dec
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              Y: 2023
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