Penumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial.

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Title: Penumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial.
Authors: Poli S; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany., Mbroh J; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany., Baron JC; Department of Neurology, Hopital Sainte-Anne, Universite de Paris, Paris, France., Singhal AB; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Strbian D; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Molina C; Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain., Lemmens R; Department of Neurosciences, Experimental Neurology, KU Leuven, University of Leuven, Leuven, Belgium.; Department of Neurology, University Hospitals Leuven, Leuven, Belgium., Turc G; Department of Neurology, Hopital Sainte-Anne, Universite de Paris, Paris, France.; Department of Neurology, GHU Paris Psychiatrie et Neurosciences INSERM U1266 Universite Paris Cite FHU NeuroVasc, Paris, France., Mikulik R; Department of Neurology, St. Anne's University Hospital Brno and Masaryk University, Brno, Czech Republic., Michel P; Neurosciences Cliniques, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland., Tatlisumak T; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden., Audebert HJ; Department of Neurology and Center for Stroke Research Berlin, Charite Universitatsmedizin Berlin, Berlin, Germany., Dichgans M; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.; German Centre for Cardiovascular Research (DZHK, Munich), Munich, Germany., Veltkamp R; Department of Neurology, Alfried Krupp Hospital, Essen, Germany.; Department of Brain Sciences, Imperial College London, London, UK., Hüsing J; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany.; Landeskrebsregister Nordrhein-Westfalen, Bochum, Germany., Graessner H; Center for Rare Diseases, Eberhard-Karls University, Tubingen, Germany., Fiehler J; Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.; Eppdata GmbH, Hamburg, Germany., Montaner J; Vall d'Hebron Institut de Recerca, Neurovascular Research Lab, Barcelona, Spain., Adeyemi AK; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany., Althaus K; Department of Neurology, University Hospital of Ulm, Ulm, Germany., Arenillas JF; Hospital Clinico Universitario de Valladolid, Valladolid, Spain., Bender B; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany., Benedikt F; Department of Neurology, University Hospital Essen, Essen, Germany., Broocks G; Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Burghaus I; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany., Cardona P; Department of Neurology, Hospital University de Bellvitge, Barcelona, Spain., Deb-Chatterji M; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Cviková M; Department of Neurology, St. Anne's University Hospital in Brno, Faculty of Medicine Masaryk University, Brno, Czech Republic., Defreyne L; Department of Vascular and Interventional Radiology, Ghent University Hospital, Ghent, Belgium., De Herdt V; Department of Neurology, Ghent University Hospital, Ghent, Belgium., Detante O; Neurology, CHU Grenoble Alpes, Grenoble, France.; Inserm, U1216, Grenoble Institut Neurosciences, Université Grenoble Alpes, Grenoble, France., Ernemann U; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany., Flottmann F; Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., García Guillamón L; Vall d'Hebron Institut de Recerca, Neurovascular Research Lab, Barcelona, Spain., Glauch M; Center for Rare Diseases, Eberhard-Karls University, Tubingen, Germany., Gomez-Exposito A; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany., Gory B; Department of Diagnostic and Therapeutic Neuroradiology, Centre Hospital Regional Universitaire de Nancy, Universite de Lorraine, INSERM U1254, Nancy, France., Sylvie Grand S; Inserm, U1216, Grenoble Institut Neurosciences, Université Grenoble Alpes, Grenoble, France.; Neuroradiology / MRI Department, CHU Grenoble Alpes, Grenoble, France., Haršány M; Department of Neurology, St. Anne's University Hospital in Brno, Faculty of Medicine Masaryk University, Brno, Czech Republic.; International Clinical Research Centre, St. Anne's University Hospital in Brno, Brno, Czech Republic., Hauser TK; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany., Heck O; Neuroradiology / MRI Department, CHU Grenoble Alpes, Grenoble, France., Hemelsoet D; Department of Neurology, Ghent University Hospital, Ghent, Belgium., Hennersdorf F; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany., Hoppe J; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Kalmbach P; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany., Kellert L; Department of Neurology, Ludwig Maximilian University (LMU), Munich, Germany., Köhrmann M; Department of Neurology, University Hospital Essen, Essen, Germany., Kowarik M; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany., Lara-Rodríguez B; Department of Neurology, Hospital University de Bellvitge, Barcelona, Spain., Legris L; Neurology, CHU Grenoble Alpes, Grenoble, France.; Inserm, U1216, Grenoble Institut Neurosciences, Université Grenoble Alpes, Grenoble, France., Lindig T; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany., Luntz S; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany., Lusk J; Duke University School of Medicine, Durham, NC, USA., Mac Grory B; Duke University School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Durham, NC, USA.; Department of Neurology, Duke University School of Medicine, Durham, NC, USA., Manger A; Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls University, Tubingen, Germany., Martinez-Majander N; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Mengel A; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany., Meyne J; Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany., Müller S; Department of Neurology, University Hospital of Ulm, Ulm, Germany., Mundiyanapurath S; Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany., Naggara O; Department of Neuroradiology, GHU Paris Psychiatrie et Neurosciences INSERM U1266 Universite Paris Cite FHU NeuroVasc, Paris, France., Nedeltchev K; Department of Neurology, KSA Kantonsspital Aarau and University of Bern, Bern, Switzerland., Nguyen TN; Department of Radiology, Boston Medical Center, Boston, MA, USA.; Department of Neurology, Boston Medical Center, Boston, MA, USA., Nilsson MA; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany., Obadia M; Department of Neurology and Stroke Center, Hopital fondation Adolphe de Rothschild, Paris, France., Poli K; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany., Purrucker JC; Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany., Räty S; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Richard S; Centre Hospital Regional Universitaire de Nancy, Nancy, France., Richter H; Department of Infectiology, Eberhard-Karls-University, Tuebingen, Germany., Schilte C; Department of Anaesthesia and Critical Care, CHU Grenoble Alpes, Grenoble, France., Schlemm E; Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Stöhr L; European Clinical Research Infrastructure Network (ECRIN), Paris, France., Stolte B; Department of Neurology, University Hospital Essen, Essen, Germany., Sykora M; Department of Neurology, St. John's Hospital, Vienna, Austria., Thomalla G; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Tomppo L; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., van Horn N; Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Zeller J; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany., Ziemann U; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany., Zuern CS; Department of Cardiology, Universitatsspital Basel, Basel, Switzerland., Härtig F; Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls University, Tubingen, Germany., Tuennerhoff J; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany.
Corporate Authors: PROOF investigators
Source: International journal of stroke : official journal of the International Stroke Society [Int J Stroke] 2024 Jan; Vol. 19 (1), pp. 120-126. Date of Electronic Publication: 2023 Aug 18.
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101274068 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4949 (Electronic) Linking ISSN: 17474930 NLM ISO Abbreviation: Int J Stroke Subsets: MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Penumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Poli+S%22">Poli S</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Mbroh+J%22">Mbroh J</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Baron+JC%22">Baron JC</searchLink>; Department of Neurology, Hopital Sainte-Anne, Universite de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Singhal+AB%22">Singhal AB</searchLink>; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Strbian+D%22">Strbian D</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Molina+C%22">Molina C</searchLink>; Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Lemmens+R%22">Lemmens R</searchLink>; Department of Neurosciences, Experimental Neurology, KU Leuven, University of Leuven, Leuven, Belgium.; Department of Neurology, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Turc+G%22">Turc G</searchLink>; Department of Neurology, Hopital Sainte-Anne, Universite de Paris, Paris, France.; Department of Neurology, GHU Paris Psychiatrie et Neurosciences INSERM U1266 Universite Paris Cite FHU NeuroVasc, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mikulik+R%22">Mikulik R</searchLink>; Department of Neurology, St. Anne's University Hospital Brno and Masaryk University, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Michel+P%22">Michel P</searchLink>; Neurosciences Cliniques, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tatlisumak+T%22">Tatlisumak T</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.; Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Audebert+HJ%22">Audebert HJ</searchLink>; Department of Neurology and Center for Stroke Research Berlin, Charite Universitatsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Dichgans+M%22">Dichgans M</searchLink>; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.; German Centre for Cardiovascular Research (DZHK, Munich), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Veltkamp+R%22">Veltkamp R</searchLink>; Department of Neurology, Alfried Krupp Hospital, Essen, Germany.; Department of Brain Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hüsing+J%22">Hüsing J</searchLink>; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany.; Landeskrebsregister Nordrhein-Westfalen, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Graessner+H%22">Graessner H</searchLink>; Center for Rare Diseases, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Fiehler+J%22">Fiehler J</searchLink>; Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.; Eppdata GmbH, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Montaner+J%22">Montaner J</searchLink>; Vall d'Hebron Institut de Recerca, Neurovascular Research Lab, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Adeyemi+AK%22">Adeyemi AK</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Althaus+K%22">Althaus K</searchLink>; Department of Neurology, University Hospital of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Arenillas+JF%22">Arenillas JF</searchLink>; Hospital Clinico Universitario de Valladolid, Valladolid, Spain.<br /><searchLink fieldCode="AU" term="%22Bender+B%22">Bender B</searchLink>; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Benedikt+F%22">Benedikt F</searchLink>; Department of Neurology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Broocks+G%22">Broocks G</searchLink>; Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Burghaus+I%22">Burghaus I</searchLink>; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Cardona+P%22">Cardona P</searchLink>; Department of Neurology, Hospital University de Bellvitge, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Deb-Chatterji+M%22">Deb-Chatterji M</searchLink>; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Cviková+M%22">Cviková M</searchLink>; Department of Neurology, St. Anne's University Hospital in Brno, Faculty of Medicine Masaryk University, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Defreyne+L%22">Defreyne L</searchLink>; Department of Vascular and Interventional Radiology, Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Herdt+V%22">De Herdt V</searchLink>; Department of Neurology, Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Detante+O%22">Detante O</searchLink>; Neurology, CHU Grenoble Alpes, Grenoble, France.; Inserm, U1216, Grenoble Institut Neurosciences, Université Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Ernemann+U%22">Ernemann U</searchLink>; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Flottmann+F%22">Flottmann F</searchLink>; Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22García+Guillamón+L%22">García Guillamón L</searchLink>; Vall d'Hebron Institut de Recerca, Neurovascular Research Lab, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Glauch+M%22">Glauch M</searchLink>; Center for Rare Diseases, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Gomez-Exposito+A%22">Gomez-Exposito A</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Gory+B%22">Gory B</searchLink>; Department of Diagnostic and Therapeutic Neuroradiology, Centre Hospital Regional Universitaire de Nancy, Universite de Lorraine, INSERM U1254, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Sylvie+Grand+S%22">Sylvie Grand S</searchLink>; Inserm, U1216, Grenoble Institut Neurosciences, Université Grenoble Alpes, Grenoble, France.; Neuroradiology / MRI Department, CHU Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Haršány+M%22">Haršány M</searchLink>; Department of Neurology, St. Anne's University Hospital in Brno, Faculty of Medicine Masaryk University, Brno, Czech Republic.; International Clinical Research Centre, St. Anne's University Hospital in Brno, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Hauser+TK%22">Hauser TK</searchLink>; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Heck+O%22">Heck O</searchLink>; Neuroradiology / MRI Department, CHU Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Hemelsoet+D%22">Hemelsoet D</searchLink>; Department of Neurology, Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Hennersdorf+F%22">Hennersdorf F</searchLink>; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hoppe+J%22">Hoppe J</searchLink>; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kalmbach+P%22">Kalmbach P</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Kellert+L%22">Kellert L</searchLink>; Department of Neurology, Ludwig Maximilian University (LMU), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Köhrmann+M%22">Köhrmann M</searchLink>; Department of Neurology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Kowarik+M%22">Kowarik M</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Lara-Rodríguez+B%22">Lara-Rodríguez B</searchLink>; Department of Neurology, Hospital University de Bellvitge, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Legris+L%22">Legris L</searchLink>; Neurology, CHU Grenoble Alpes, Grenoble, France.; Inserm, U1216, Grenoble Institut Neurosciences, Université Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Lindig+T%22">Lindig T</searchLink>; Department of Diagnostic and Interventional Neuroradiology, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Luntz+S%22">Luntz S</searchLink>; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lusk+J%22">Lusk J</searchLink>; Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Mac+Grory+B%22">Mac Grory B</searchLink>; Duke University School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Durham, NC, USA.; Department of Neurology, Duke University School of Medicine, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Manger+A%22">Manger A</searchLink>; Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Martinez-Majander+N%22">Martinez-Majander N</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Mengel+A%22">Mengel A</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Meyne+J%22">Meyne J</searchLink>; Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+S%22">Müller S</searchLink>; Department of Neurology, University Hospital of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Mundiyanapurath+S%22">Mundiyanapurath S</searchLink>; Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Naggara+O%22">Naggara O</searchLink>; Department of Neuroradiology, GHU Paris Psychiatrie et Neurosciences INSERM U1266 Universite Paris Cite FHU NeuroVasc, Paris, France.<br /><searchLink fieldCode="AU" term="%22Nedeltchev+K%22">Nedeltchev K</searchLink>; Department of Neurology, KSA Kantonsspital Aarau and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nguyen+TN%22">Nguyen TN</searchLink>; Department of Radiology, Boston Medical Center, Boston, MA, USA.; Department of Neurology, Boston Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nilsson+MA%22">Nilsson MA</searchLink>; Coordinating Centre for Clinical Trials, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Obadia+M%22">Obadia M</searchLink>; Department of Neurology and Stroke Center, Hopital fondation Adolphe de Rothschild, Paris, France.<br /><searchLink fieldCode="AU" term="%22Poli+K%22">Poli K</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Purrucker+JC%22">Purrucker JC</searchLink>; Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Räty+S%22">Räty S</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Richard+S%22">Richard S</searchLink>; Centre Hospital Regional Universitaire de Nancy, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Richter+H%22">Richter H</searchLink>; Department of Infectiology, Eberhard-Karls-University, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schilte+C%22">Schilte C</searchLink>; Department of Anaesthesia and Critical Care, CHU Grenoble Alpes, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Schlemm+E%22">Schlemm E</searchLink>; Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stöhr+L%22">Stöhr L</searchLink>; European Clinical Research Infrastructure Network (ECRIN), Paris, France.<br /><searchLink fieldCode="AU" term="%22Stolte+B%22">Stolte B</searchLink>; Department of Neurology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Sykora+M%22">Sykora M</searchLink>; Department of Neurology, St. John's Hospital, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Thomalla+G%22">Thomalla G</searchLink>; Department of Neurology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Tomppo+L%22">Tomppo L</searchLink>; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22van+Horn+N%22">van Horn N</searchLink>; Department of Neuroradiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zeller+J%22">Zeller J</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ziemann+U%22">Ziemann U</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Zuern+CS%22">Zuern CS</searchLink>; Department of Cardiology, Universitatsspital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Härtig+F%22">Härtig F</searchLink>; Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls University, Tubingen, Germany.<br /><searchLink fieldCode="AU" term="%22Tuennerhoff+J%22">Tuennerhoff J</searchLink>; Department of Neurology & Stroke, Eberhard-Karls University, University Hospital, Tubingen, Germany.; Hertie Institute for Clinical Brain Research, Eberhard-Karls University, Tubingen, Germany.
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  Data: <searchLink fieldCode="CA" term="%22PROOF+investigators%22">PROOF investigators</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101274068%22">International journal of stroke : official journal of the International Stroke Society</searchLink> [Int J Stroke] 2024 Jan; Vol. 19 (1), pp. 120-126. <i>Date of Electronic Publication: </i>2023 Aug 18.
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  Data: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101274068 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1747-4949 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217474930%22">17474930 </searchLink><i>NLM ISO Abbreviation: </i>Int J Stroke <i>Subsets: </i>MEDLINE
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        Value: 10.1177/17474930231185275
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        Text: English
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      – TitleFull: Penumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial.
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            – D: 01
              M: 01
              Text: 2024 Jan
              Type: published
              Y: 2024
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              Value: 1747-4949
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              Value: 19
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            – TitleFull: International journal of stroke : official journal of the International Stroke Society
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