Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis.
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| Title: | Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis. |
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| Authors: | Sanyal AJ; Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: arun.sanyal@vcuhealth.org., Ratziu V; Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Institute for Cardiometabolism and Nutrition, Paris, France., Loomba R; University of California, San Diego, La Jolla, CA, USA., Anstee QM; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle Upon Tyne, UK; Newcastle NIHR Biomedical Research Center, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK., Kowdley KV; Liver Institute Northwest, Seattle, WA, USA., Rinella ME; University of Chicago, Pritzker School of Medicine, Chicago, IL, USA., Sheikh MY; Fresno Clinical Research Center, Fresno, CA, USA., Trotter JF; Baylor Health, Liver Consultants of Texas, Dallas, TX, USA., Knapple W; Arkansas Gastroenterology, North Little Rock, AR, USA., Lawitz EJ; Texas Liver Institute, University of Texas Health San Antonio, San Antonio, TX, USA., Abdelmalek MF; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA., Newsome PN; National Institute for Health Research Birmingham Biomedical Research Centre, Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK., Boursier J; Angers University Hospital, Angers University, Angers, France., Mathurin P; Hepatogastroenterology, CHU Lille, Lille, France., Dufour JF; Center for Digestive Diseases, Lausanne, Switzerland., Berrey MM; Intercept Pharmaceuticals, Morristown, NJ, USA., Shiff SJ; Intercept Pharmaceuticals, Morristown, NJ, USA., Sawhney S; Intercept Pharmaceuticals, Morristown, NJ, USA., Capozza T; Intercept Pharmaceuticals, Morristown, NJ, USA., Leyva R; Intercept Pharmaceuticals, Morristown, NJ, USA., Harrison SA; Pinnacle Clinical Research Center, San Antonio, TX, USA., Younossi ZM; Beatty Liver and Obesity Research Program, Center for Liver Diseases, Inova Medicine, Falls Church, VA, USA. |
| Source: | Journal of hepatology [J Hepatol] 2023 Nov; Vol. 79 (5), pp. 1110-1120. Date of Electronic Publication: 2023 Jul 28. |
| Publication Type: | Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37517454 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sanyal+AJ%22">Sanyal AJ</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: arun.sanyal@vcuhealth.org.<br /><searchLink fieldCode="AU" term="%22Ratziu+V%22">Ratziu V</searchLink>; Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Institute for Cardiometabolism and Nutrition, Paris, France.<br /><searchLink fieldCode="AU" term="%22Loomba+R%22">Loomba R</searchLink>; University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Anstee+QM%22">Anstee QM</searchLink>; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle Upon Tyne, UK; Newcastle NIHR Biomedical Research Center, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Kowdley+KV%22">Kowdley KV</searchLink>; Liver Institute Northwest, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rinella+ME%22">Rinella ME</searchLink>; University of Chicago, Pritzker School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Sheikh+MY%22">Sheikh MY</searchLink>; Fresno Clinical Research Center, Fresno, CA, USA.<br /><searchLink fieldCode="AU" term="%22Trotter+JF%22">Trotter JF</searchLink>; Baylor Health, Liver Consultants of Texas, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Knapple+W%22">Knapple W</searchLink>; Arkansas Gastroenterology, North Little Rock, AR, USA.<br /><searchLink fieldCode="AU" term="%22Lawitz+EJ%22">Lawitz EJ</searchLink>; Texas Liver Institute, University of Texas Health San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Abdelmalek+MF%22">Abdelmalek MF</searchLink>; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Newsome+PN%22">Newsome PN</searchLink>; National Institute for Health Research Birmingham Biomedical Research Centre, Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Boursier+J%22">Boursier J</searchLink>; Angers University Hospital, Angers University, Angers, France.<br /><searchLink fieldCode="AU" term="%22Mathurin+P%22">Mathurin P</searchLink>; Hepatogastroenterology, CHU Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Dufour+JF%22">Dufour JF</searchLink>; Center for Digestive Diseases, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Berrey+MM%22">Berrey MM</searchLink>; Intercept Pharmaceuticals, Morristown, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Shiff+SJ%22">Shiff SJ</searchLink>; Intercept Pharmaceuticals, Morristown, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Sawhney+S%22">Sawhney S</searchLink>; Intercept Pharmaceuticals, Morristown, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Capozza+T%22">Capozza T</searchLink>; Intercept Pharmaceuticals, Morristown, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Leyva+R%22">Leyva R</searchLink>; Intercept Pharmaceuticals, Morristown, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Harrison+SA%22">Harrison SA</searchLink>; Pinnacle Clinical Research Center, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Younossi+ZM%22">Younossi ZM</searchLink>; Beatty Liver and Obesity Research Program, Center for Liver Diseases, Inova Medicine, Falls Church, VA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228503886%22">Journal of hepatology</searchLink> [J Hepatol] 2023 Nov; Vol. 79 (5), pp. 1110-1120. <i>Date of Electronic Publication: </i>2023 Jul 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8503886 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1600-0641 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201688278%22">01688278 </searchLink><i>NLM ISO Abbreviation: </i>J Hepatol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37517454 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jhep.2023.07.014 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1110 Titles: – TitleFull: Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sanyal AJ – PersonEntity: Name: NameFull: Ratziu V – PersonEntity: Name: NameFull: Loomba R – PersonEntity: Name: NameFull: Anstee QM – PersonEntity: Name: NameFull: Kowdley KV – PersonEntity: Name: NameFull: Rinella ME – PersonEntity: Name: NameFull: Sheikh MY – PersonEntity: Name: NameFull: Trotter JF – PersonEntity: Name: NameFull: Knapple W – PersonEntity: Name: NameFull: Lawitz EJ – PersonEntity: Name: NameFull: Abdelmalek MF – PersonEntity: Name: NameFull: Newsome PN – PersonEntity: Name: NameFull: Boursier J – PersonEntity: Name: NameFull: Mathurin P – PersonEntity: Name: NameFull: Dufour JF – PersonEntity: Name: NameFull: Berrey MM – PersonEntity: Name: NameFull: Shiff SJ – PersonEntity: Name: NameFull: Sawhney S – PersonEntity: Name: NameFull: Capozza T – PersonEntity: Name: NameFull: Leyva R – PersonEntity: Name: NameFull: Harrison SA – PersonEntity: Name: NameFull: Younossi ZM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: 2023 Nov Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1600-0641 Numbering: – Type: volume Value: 79 – Type: issue Value: 5 Titles: – TitleFull: Journal of hepatology Type: main |
| ResultId | 1 |
