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Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor.

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Title: Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor.
Authors: D'Erasmo MP; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Akins NS; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Ma P; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Jing Y; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Swanger SA; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Sharma SK; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Bartsch PW; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Menaldino DS; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Arcoria PJ; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Bui TT; INMED, INSERM, Aix Marseille University, 13284 Marseille, France., Pons-Bennaceur A; INMED, INSERM, Aix Marseille University, 13284 Marseille, France., Le P; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Allen JP; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Ullman EZ; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Nocilla KA; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Zhang J; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Perszyk RE; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Kim S; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Acker TM; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Taz A; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Burton SL; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Coe K; Janssen Research & Development, LLC, San Diego, California 92121, United States., Fritzemeier RG; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Burnashev N; INMED, INSERM, Aix Marseille University, 13284 Marseille, France., Yuan H; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States., Liotta DC; Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States., Traynelis SF; Department of Pharmacology and Chemical Biology, Emory University, Atlanta, Georgia 30322, United States.
Source: ACS chemical neuroscience [ACS Chem Neurosci] 2023 Sep 06; Vol. 14 (17), pp. 3059-3076. Date of Electronic Publication: 2023 Aug 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101525337 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1948-7193 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219487193%22">19487193 </searchLink><i>NLM ISO Abbreviation: </i>ACS Chem Neurosci <i>Subsets: </i>MEDLINE
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