GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling.
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| Title: | GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling. |
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| Authors: | Fuchs CD; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Claudel T; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Mlitz V; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Riva A; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Menz M; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Brusilovskaya K; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Vienna Experimental Hepatic Hemodynamic Lab (HEPEX), Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Portal Hypertension and Liver fibrosis, Medical University of Vienna, Vienna, Austria., Haller F; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Baumgartner M; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Königshofer P; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Vienna Experimental Hepatic Hemodynamic Lab (HEPEX), Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Portal Hypertension and Liver fibrosis, Medical University of Vienna, Vienna, Austria., Unger LW; Division of Visceral Surgery, Department of General Surgery, Medical University of Vienna, Vienna, Austria., Sjöland W; Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Stojakovic T; Clinical Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Graz, Graz, Austria., Busslinger G; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Reiberger T; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Vienna Experimental Hepatic Hemodynamic Lab (HEPEX), Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Portal Hypertension and Liver fibrosis, Medical University of Vienna, Vienna, Austria., Marschall HU; Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Trauner M; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address: michael.trauner@meduniwien.ac.at. |
| Source: | Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2023; Vol. 16 (5), pp. 847-856. Date of Electronic Publication: 2023 Aug 10. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37572734 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2<superscript>-/-</superscript> Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Fuchs+CD%22">Fuchs CD</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Claudel+T%22">Claudel T</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Mlitz+V%22">Mlitz V</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Riva+A%22">Riva A</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Menz+M%22">Menz M</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Brusilovskaya+K%22">Brusilovskaya K</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Vienna Experimental Hepatic Hemodynamic Lab (HEPEX), Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Portal Hypertension and Liver fibrosis, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Haller+F%22">Haller F</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Baumgartner+M%22">Baumgartner M</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Königshofer+P%22">Königshofer P</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Vienna Experimental Hepatic Hemodynamic Lab (HEPEX), Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Portal Hypertension and Liver fibrosis, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Unger+LW%22">Unger LW</searchLink>; Division of Visceral Surgery, Department of General Surgery, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Sjöland+W%22">Sjöland W</searchLink>; Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Scharnagl+H%22">Scharnagl H</searchLink>; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Stojakovic+T%22">Stojakovic T</searchLink>; Clinical Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Busslinger+G%22">Busslinger G</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Reiberger+T%22">Reiberger T</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; Vienna Experimental Hepatic Hemodynamic Lab (HEPEX), Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Portal Hypertension and Liver fibrosis, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Marschall+HU%22">Marschall HU</searchLink>; Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Trauner+M%22">Trauner M</searchLink>; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address: michael.trauner@meduniwien.ac.at. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101648302%22">Cellular and molecular gastroenterology and hepatology</searchLink> [Cell Mol Gastroenterol Hepatol] 2023; Vol. 16 (5), pp. 847-856. <i>Date of Electronic Publication: </i>2023 Aug 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Gastroenterological+Association%22">American Gastroenterological Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101648302 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2352-345X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222352345X%22">2352345X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Gastroenterol Hepatol <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jcmgh.2023.08.003 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 847 Titles: – TitleFull: GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Fuchs CD – PersonEntity: Name: NameFull: Claudel T – PersonEntity: Name: NameFull: Mlitz V – PersonEntity: Name: NameFull: Riva A – PersonEntity: Name: NameFull: Menz M – PersonEntity: Name: NameFull: Brusilovskaya K – PersonEntity: Name: NameFull: Haller F – PersonEntity: Name: NameFull: Baumgartner M – PersonEntity: Name: NameFull: Königshofer P – PersonEntity: Name: NameFull: Unger LW – PersonEntity: Name: NameFull: Sjöland W – PersonEntity: Name: NameFull: Scharnagl H – PersonEntity: Name: NameFull: Stojakovic T – PersonEntity: Name: NameFull: Busslinger G – PersonEntity: Name: NameFull: Reiberger T – PersonEntity: Name: NameFull: Marschall HU – PersonEntity: Name: NameFull: Trauner M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2023 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 2352-345X Numbering: – Type: volume Value: 16 – Type: issue Value: 5 Titles: – TitleFull: Cellular and molecular gastroenterology and hepatology Type: main |
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