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A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis.

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Title: A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis.
Authors: Bergkamp ND; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., van Senten JR; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Brink HJ; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Bebelman MP; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., van den Bor J; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Çobanoğlu TS; Department of Chemistry and Pharmaceutical Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Dinkla K; IBM Research, Rüschlikon, Switzerland., Köster J; Algorithms for Reproducible Bioinformatics, Institute of Human Genetics, Faculty of Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Medical Oncology, Harvard Medical School, Harvard University, Boston, MA, USA., Klau G; Algorithmic Bioinformatics, Department of Computer Science, Heinrich Heine University, Düsseldorf, Germany., Siderius M; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Smit MJ; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Source: Science signaling [Sci Signal] 2023 Aug 15; Vol. 16 (798), pp. eade6737. Date of Electronic Publication: 2023 Aug 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P<subscript>1</subscript> signaling axis.
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  Data: <searchLink fieldCode="AU" term="%22Bergkamp+ND%22">Bergkamp ND</searchLink>; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Senten+JR%22">van Senten JR</searchLink>; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Brink+HJ%22">Brink HJ</searchLink>; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bebelman+MP%22">Bebelman MP</searchLink>; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Bor+J%22">van den Bor J</searchLink>; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Çobanoğlu+TS%22">Çobanoğlu TS</searchLink>; Department of Chemistry and Pharmaceutical Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Dinkla+K%22">Dinkla K</searchLink>; IBM Research, Rüschlikon, Switzerland.<br /><searchLink fieldCode="AU" term="%22Köster+J%22">Köster J</searchLink>; Algorithms for Reproducible Bioinformatics, Institute of Human Genetics, Faculty of Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Medical Oncology, Harvard Medical School, Harvard University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Klau+G%22">Klau G</searchLink>; Algorithmic Bioinformatics, Department of Computer Science, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Siderius+M%22">Siderius M</searchLink>; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Smit+MJ%22">Smit MJ</searchLink>; Amsterdam Institute for Molecular and Life Sciences (AIMMS), Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101465400%22">Science signaling</searchLink> [Sci Signal] 2023 Aug 15; Vol. 16 (798), pp. eade6737. <i>Date of Electronic Publication: </i>2023 Aug 15.
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