Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.
Saved in:
| Title: | Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal. |
|---|---|
| Authors: | Krill-Burger JM; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Dempster JM; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Borah AA; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Paolella BR; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Root DE; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Golub TR; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Boehm JS; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Hahn WC; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., McFarland JM; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Vazquez F; Broad Institute of Harvard and MIT, Cambridge, MA, USA. vazquez@broadinstitute.org.; Dana-Farber Cancer Institute, Boston, MA, USA. vazquez@broadinstitute.org., Tsherniak A; Broad Institute of Harvard and MIT, Cambridge, MA, USA. |
| Source: | Genome biology [Genome Biol] 2023 Aug 23; Vol. 24 (1), pp. 192. Date of Electronic Publication: 2023 Aug 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1474-760X |
|---|---|
| DOI: | 10.1186/s13059-023-03020-w |
