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Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.

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Title: Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.
Authors: Krill-Burger JM; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Dempster JM; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Borah AA; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Paolella BR; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Root DE; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Golub TR; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Boehm JS; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Hahn WC; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., McFarland JM; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Vazquez F; Broad Institute of Harvard and MIT, Cambridge, MA, USA. vazquez@broadinstitute.org.; Dana-Farber Cancer Institute, Boston, MA, USA. vazquez@broadinstitute.org., Tsherniak A; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Source: Genome biology [Genome Biol] 2023 Aug 23; Vol. 24 (1), pp. 192. Date of Electronic Publication: 2023 Aug 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.
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  Data: <searchLink fieldCode="AU" term="%22Krill-Burger+JM%22">Krill-Burger JM</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dempster+JM%22">Dempster JM</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Borah+AA%22">Borah AA</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Paolella+BR%22">Paolella BR</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Root+DE%22">Root DE</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Golub+TR%22">Golub TR</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boehm+JS%22">Boehm JS</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hahn+WC%22">Hahn WC</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22McFarland+JM%22">McFarland JM</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Vazquez+F%22">Vazquez F</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA. vazquez@broadinstitute.org.; Dana-Farber Cancer Institute, Boston, MA, USA. vazquez@broadinstitute.org.<br /><searchLink fieldCode="AU" term="%22Tsherniak+A%22">Tsherniak A</searchLink>; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
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  Data: <searchLink fieldCode="JN" term="%22100960660%22">Genome biology</searchLink> [Genome Biol] 2023 Aug 23; Vol. 24 (1), pp. 192. <i>Date of Electronic Publication: </i>2023 Aug 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100960660 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-760X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214747596%22">14747596 </searchLink><i>NLM ISO Abbreviation: </i>Genome Biol <i>Subsets: </i>MEDLINE
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