Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate.
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| Title: | Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate. |
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| Authors: | Graboski AL; Department of Pharmacology, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Kowalewski ME; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Simpson JB; Department of Chemistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Cao X; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA., Ha M; Department of Chemistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Zhang J; Department of Chemistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Walton WG; Department of Chemistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA., Flaherty DP; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA., Redinbo MR; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA; Department of Chemistry, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: redinbo@unc.edu. |
| Source: | Cell chemical biology [Cell Chem Biol] 2023 Nov 16; Vol. 30 (11), pp. 1402-1413.e7. Date of Electronic Publication: 2023 Aug 25. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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