View in EDS

A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.

Saved in:
Bibliographic Details
Title: A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Authors: Chitty JL; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Yam M; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Perryman L; Pharmaxis, Frenchs Forest, New South Wales, Australia., Parker AL; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Skhinas JN; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Setargew YFI; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Mok ETY; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Tran E; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Grant RD; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Latham SL; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Pereira BA; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Ritchie SC; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Murphy KJ; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Trpceski M; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Findlay AD; Pharmaxis, Frenchs Forest, New South Wales, Australia., Melenec P; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Filipe EC; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Nadalini A; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Velayuthar S; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Major G; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Wyllie K; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Papanicolaou M; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Ratnaseelan S; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Phillips PA; School of Biomedical Sciences, Faculty of Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Sharbeen G; School of Biomedical Sciences, Faculty of Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Youkhana J; School of Biomedical Sciences, Faculty of Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia., Russo A; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Blackwell A; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Hastings JF; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Lucas MC; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Chambers CR; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Reed DA; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Stoehr J; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Vennin C; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Pidsley R; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Zaratzian A; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Da Silva AM; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Tayao M; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Charlton B; Pharmaxis, Frenchs Forest, New South Wales, Australia., Herrmann D; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Nobis M; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; Intravital Imaging Expertise Center, VIB Center for Cancer Biology, VIB, Leuven, Belgium., Clark SJ; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Biankin AV; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK.; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK., Johns AL; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Croucher DR; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Nagrial A; Department of Medical Oncology, Westmead Hospital, Sydney, New South Wales, Australia., Gill AJ; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.; NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, New South Wales, Australia.; Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, Sydney, New South Wales, Australia., Grimmond SM; University of Melbourne Centre for Cancer Research, VCCC, Melbourne, Victoria, Australia., Pajic M; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia., Timpson P; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia., Jarolimek W; Pharmaxis, Frenchs Forest, New South Wales, Australia. wolfgang.jarolimek@pharmaxis.com.au., Cox TR; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia. t.cox@garvan.org.au.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia. t.cox@garvan.org.au.
Corporate Authors: Australian Pancreatic Cancer Genome Initiative (APGI), Australian Pancreatic Cancer Matrix Atlas (APMA)
Source: Nature cancer [Nat Cancer] 2023 Sep; Vol. 4 (9), pp. 1326-1344. Date of Electronic Publication: 2023 Aug 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 37640930
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Chitty+JL%22">Chitty JL</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Yam+M%22">Yam M</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Perryman+L%22">Perryman L</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Parker+AL%22">Parker AL</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Skhinas+JN%22">Skhinas JN</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Setargew+YFI%22">Setargew YFI</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Mok+ETY%22">Mok ETY</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Tran+E%22">Tran E</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Grant+RD%22">Grant RD</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Latham+SL%22">Latham SL</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Pereira+BA%22">Pereira BA</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Ritchie+SC%22">Ritchie SC</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Murphy+KJ%22">Murphy KJ</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Trpceski+M%22">Trpceski M</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Findlay+AD%22">Findlay AD</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Melenec+P%22">Melenec P</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Filipe+EC%22">Filipe EC</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Nadalini+A%22">Nadalini A</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Velayuthar+S%22">Velayuthar S</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Major+G%22">Major G</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Wyllie+K%22">Wyllie K</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Papanicolaou+M%22">Papanicolaou M</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Ratnaseelan+S%22">Ratnaseelan S</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Phillips+PA%22">Phillips PA</searchLink>; School of Biomedical Sciences, Faculty of Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Sharbeen+G%22">Sharbeen G</searchLink>; School of Biomedical Sciences, Faculty of Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Youkhana+J%22">Youkhana J</searchLink>; School of Biomedical Sciences, Faculty of Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Russo+A%22">Russo A</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Blackwell+A%22">Blackwell A</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Hastings+JF%22">Hastings JF</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Lucas+MC%22">Lucas MC</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Chambers+CR%22">Chambers CR</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Reed+DA%22">Reed DA</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Stoehr+J%22">Stoehr J</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Vennin+C%22">Vennin C</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Pidsley+R%22">Pidsley R</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Zaratzian+A%22">Zaratzian A</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Da+Silva+AM%22">Da Silva AM</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Tayao+M%22">Tayao M</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Charlton+B%22">Charlton B</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Herrmann+D%22">Herrmann D</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Nobis+M%22">Nobis M</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; Intravital Imaging Expertise Center, VIB Center for Cancer Biology, VIB, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Clark+SJ%22">Clark SJ</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Biankin+AV%22">Biankin AV</searchLink>; Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, UK.; West of Scotland Pancreatic Unit, Glasgow Royal Infirmary, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Johns+AL%22">Johns AL</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Croucher+DR%22">Croucher DR</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Nagrial+A%22">Nagrial A</searchLink>; Department of Medical Oncology, Westmead Hospital, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Gill+AJ%22">Gill AJ</searchLink>; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.; NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, New South Wales, Australia.; Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medical Research, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Grimmond+SM%22">Grimmond SM</searchLink>; University of Melbourne Centre for Cancer Research, VCCC, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pajic+M%22">Pajic M</searchLink>; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.; The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Timpson+P%22">Timpson P</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Jarolimek+W%22">Jarolimek W</searchLink>; Pharmaxis, Frenchs Forest, New South Wales, Australia. wolfgang.jarolimek@pharmaxis.com.au.<br /><searchLink fieldCode="AU" term="%22Cox+TR%22">Cox TR</searchLink>; Cancer Ecosystems Program, The Garvan Institute of Medical Research and The Kinghorn Cancer Centre, Darlinghurst, New South Wales, Australia. t.cox@garvan.org.au.; School of Clinical Medicine, St Vincent's Healthcare Clinical Campus, UNSW Medicine and Health, UNSW Sydney, Sydney, New South Wales, Australia. t.cox@garvan.org.au.
– Name: AuthorCorporate
  Label: Corporate Authors
  Group: Au
  Data: <searchLink fieldCode="CA" term="%22Australian+Pancreatic+Cancer+Genome+Initiative+%28APGI%29%22">Australian Pancreatic Cancer Genome Initiative (APGI)</searchLink><br /><searchLink fieldCode="CA" term="%22Australian+Pancreatic+Cancer+Matrix+Atlas+%28APMA%29%22">Australian Pancreatic Cancer Matrix Atlas (APMA)</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2023 Sep; Vol. 4 (9), pp. 1326-1344. <i>Date of Electronic Publication: </i>2023 Aug 28.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101761119 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-1347 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226621347%22">26621347 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cancer <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37640930
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s43018-023-00614-y
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1326
    Titles:
      – TitleFull: A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Chitty JL
      – PersonEntity:
          Name:
            NameFull: Yam M
      – PersonEntity:
          Name:
            NameFull: Perryman L
      – PersonEntity:
          Name:
            NameFull: Parker AL
      – PersonEntity:
          Name:
            NameFull: Skhinas JN
      – PersonEntity:
          Name:
            NameFull: Setargew YFI
      – PersonEntity:
          Name:
            NameFull: Mok ETY
      – PersonEntity:
          Name:
            NameFull: Tran E
      – PersonEntity:
          Name:
            NameFull: Grant RD
      – PersonEntity:
          Name:
            NameFull: Latham SL
      – PersonEntity:
          Name:
            NameFull: Pereira BA
      – PersonEntity:
          Name:
            NameFull: Ritchie SC
      – PersonEntity:
          Name:
            NameFull: Murphy KJ
      – PersonEntity:
          Name:
            NameFull: Trpceski M
      – PersonEntity:
          Name:
            NameFull: Findlay AD
      – PersonEntity:
          Name:
            NameFull: Melenec P
      – PersonEntity:
          Name:
            NameFull: Filipe EC
      – PersonEntity:
          Name:
            NameFull: Nadalini A
      – PersonEntity:
          Name:
            NameFull: Velayuthar S
      – PersonEntity:
          Name:
            NameFull: Major G
      – PersonEntity:
          Name:
            NameFull: Wyllie K
      – PersonEntity:
          Name:
            NameFull: Papanicolaou M
      – PersonEntity:
          Name:
            NameFull: Ratnaseelan S
      – PersonEntity:
          Name:
            NameFull: Phillips PA
      – PersonEntity:
          Name:
            NameFull: Sharbeen G
      – PersonEntity:
          Name:
            NameFull: Youkhana J
      – PersonEntity:
          Name:
            NameFull: Russo A
      – PersonEntity:
          Name:
            NameFull: Blackwell A
      – PersonEntity:
          Name:
            NameFull: Hastings JF
      – PersonEntity:
          Name:
            NameFull: Lucas MC
      – PersonEntity:
          Name:
            NameFull: Chambers CR
      – PersonEntity:
          Name:
            NameFull: Reed DA
      – PersonEntity:
          Name:
            NameFull: Stoehr J
      – PersonEntity:
          Name:
            NameFull: Vennin C
      – PersonEntity:
          Name:
            NameFull: Pidsley R
      – PersonEntity:
          Name:
            NameFull: Zaratzian A
      – PersonEntity:
          Name:
            NameFull: Da Silva AM
      – PersonEntity:
          Name:
            NameFull: Tayao M
      – PersonEntity:
          Name:
            NameFull: Charlton B
      – PersonEntity:
          Name:
            NameFull: Herrmann D
      – PersonEntity:
          Name:
            NameFull: Nobis M
      – PersonEntity:
          Name:
            NameFull: Clark SJ
      – PersonEntity:
          Name:
            NameFull: Biankin AV
      – PersonEntity:
          Name:
            NameFull: Johns AL
      – PersonEntity:
          Name:
            NameFull: Croucher DR
      – PersonEntity:
          Name:
            NameFull: Nagrial A
      – PersonEntity:
          Name:
            NameFull: Gill AJ
      – PersonEntity:
          Name:
            NameFull: Grimmond SM
      – PersonEntity:
          Name:
            NameFull: Pajic M
      – PersonEntity:
          Name:
            NameFull: Timpson P
      – PersonEntity:
          Name:
            NameFull: Jarolimek W
      – PersonEntity:
          Name:
            NameFull: Cox TR
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: 2023 Sep
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-electronic
              Value: 2662-1347
          Numbering:
            – Type: volume
              Value: 4
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Nature cancer
              Type: main
ResultId 1