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FOXO1 Inhibition Generates Potent Nonactivated CAR T Cells against Solid Tumors.

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Title: FOXO1 Inhibition Generates Potent Nonactivated CAR T Cells against Solid Tumors.
Authors: Marchais M; CNRS UMR9196, Physiologie et Pathologie Moléculaires des Rétrovirus Endogènes et Infectieux, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France., Simula L; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France., Phayanouvong M; INSERM UMR 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France., Mami-Chouaib F; INSERM UMR 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France., Bismuth G; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France., Decroocq J; Assistance Publique-Hôpitaux de Paris, Centre-Université de Paris, Service d'Hématologie Clinique, Hôpital Cochin, Paris, France., Bouscary D; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.; Assistance Publique-Hôpitaux de Paris, Centre-Université de Paris, Service d'Hématologie Clinique, Hôpital Cochin, Paris, France., Dutrieux J; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.; Viral DNA Integration and Chromatin Dynamics Network (DyNAVir), Paris, France., Mangeney M; CNRS UMR9196, Physiologie et Pathologie Moléculaires des Rétrovirus Endogènes et Infectieux, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.
Source: Cancer immunology research [Cancer Immunol Res] 2023 Nov 01; Vol. 11 (11), pp. 1508-1523.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Marchais+M%22">Marchais M</searchLink>; CNRS UMR9196, Physiologie et Pathologie Moléculaires des Rétrovirus Endogènes et Infectieux, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.<br /><searchLink fieldCode="AU" term="%22Simula+L%22">Simula L</searchLink>; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.<br /><searchLink fieldCode="AU" term="%22Phayanouvong+M%22">Phayanouvong M</searchLink>; INSERM UMR 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Mami-Chouaib+F%22">Mami-Chouaib F</searchLink>; INSERM UMR 1186, Integrative Tumor Immunology and Immunotherapy, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Bismuth+G%22">Bismuth G</searchLink>; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.<br /><searchLink fieldCode="AU" term="%22Decroocq+J%22">Decroocq J</searchLink>; Assistance Publique-Hôpitaux de Paris, Centre-Université de Paris, Service d'Hématologie Clinique, Hôpital Cochin, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bouscary+D%22">Bouscary D</searchLink>; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.; Assistance Publique-Hôpitaux de Paris, Centre-Université de Paris, Service d'Hématologie Clinique, Hôpital Cochin, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dutrieux+J%22">Dutrieux J</searchLink>; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.; Viral DNA Integration and Chromatin Dynamics Network (DyNAVir), Paris, France.<br /><searchLink fieldCode="AU" term="%22Mangeney+M%22">Mangeney M</searchLink>; CNRS UMR9196, Physiologie et Pathologie Moléculaires des Rétrovirus Endogènes et Infectieux, Gustave Roussy, Faculté de Médecine, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.; Université de Paris, Institut Cochin, CNRS UMR8104, INSERM U1016, Paris, France.
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