Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.

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Title: Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.
Authors: Campbell JL Jr; Ramboll US Corporation, Raleigh, NC, United States., Clewell HJ 3rd; Ramboll US Corporation, Raleigh, NC, United States., Van Landingham C; Ramboll US Corporation, Monroe, LA, United States., Gentry PR; Ramboll US Corporation, Monroe, LA, United States., Andersen ME; Andersen ToxConsulting, LLC, Chapel Hill, NC, United States.
Source: Frontiers in pharmacology [Front Pharmacol] 2023 Aug 17; Vol. 14, pp. 1223808. Date of Electronic Publication: 2023 Aug 17 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Data: Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.
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  Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2023 Aug 17; Vol. 14, pp. 1223808. <i>Date of Electronic Publication: </i>2023 Aug 17 (<i>Print Publication: </i>2023).
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        Value: 10.3389/fphar.2023.1223808
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      – TitleFull: Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.
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              Text: 2023 Aug 17
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