Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β.
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| Title: | Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1β. |
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| Authors: | Hommel U; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland. uli.hommel@icloud.com., Hurth K; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland. konstanze.hurth@novartis.com., Rondeau JM; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Vulpetti A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Ostermeier D; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Boettcher A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Brady JP; Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, MA, 02139, USA., Hediger M; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Lehmann S; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Koch E; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Blechschmidt A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Yamamoto R; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Tundo Dottorello V; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Haenni-Holzinger S; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Kaiser C; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Lehr P; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Lingel A; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Mureddu L; Leicester Institute of Structural and Chemical Biology, Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 7RH, UK., Schleberger C; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Blank J; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Ramage P; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Freuler F; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Eder J; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland., Bornancin F; Novartis Institutes for BioMedical Research, Novartis Campus, CH-4002, Basel, Switzerland. frederic.bornancin@novartis.com. |
| Source: | Nature communications [Nat Commun] 2023 Sep 07; Vol. 14 (1), pp. 5497. Date of Electronic Publication: 2023 Sep 07. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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