Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome.
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| Title: | Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome. |
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| Authors: | Li Q; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. qiuxia-li@uiowa.edu.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. qiuxia-li@uiowa.edu.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. qiuxia-li@uiowa.edu.; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine and UCLA Health, University of California-Los Angeles, Los Angeles, CA, 90095, USA. qiuxia-li@uiowa.edu., Zhang Q; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, David Geffen School of Medicine and UCLA Health, University of California-Los Angeles, Los Angeles, CA, 90095, USA., Kim YR; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Gaddam RR; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Jacobs JS; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Bachschmid MM; Boston University School of Medicine, Boston, MA, 02118, USA., Younis T; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Zhu Z; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Veterans Affairs Medical Center, Iowa City, IA, 52242, USA., Zingman L; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Veterans Affairs Medical Center, Iowa City, IA, 52242, USA., London B; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Rauckhorst AJ; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolomics Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Taylor EB; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; FOEDRC Metabolomics Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Norris AW; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; FOEDRC Metabolic Phenotyping Core Facility, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Vikram A; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Irani K; Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. Kaikobadirani@gmail.com.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. Kaikobadirani@gmail.com.; Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. Kaikobadirani@gmail.com.; Veterans Affairs Medical Center, Iowa City, IA, 52242, USA. Kaikobadirani@gmail.com.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. Kaikobadirani@gmail.com.; Pappajohn Biomedical Institute, University of Iowa Carver College of Medicine, Iowa City, IA, USA. Kaikobadirani@gmail.com. |
| Source: | Nature communications [Nat Commun] 2023 Sep 11; Vol. 14 (1), pp. 5595. Date of Electronic Publication: 2023 Sep 11. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Retracted Publication |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-41351-1 |
