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CYP2D6-guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial.

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Title: CYP2D6-guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial.
Authors: Mosley SA; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.; Department of Clinical Pharmacy, University of Southern California, Los Angeles, California, USA., Cicali E; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA., Del Cueto A; Department of Individualized Cancer Management, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Portman DG; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Donovan KA; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Gong Y; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA., Langaee T; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA., Gopalan P; Division of Hematology and Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA., Schmit J; Division of Hematology and Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA., Starr JS; Division of Hematology/Oncology, Mayo Clinic, Jacksonville, Florida, USA., Silver N; Department of Otolaryngology, College of Medicine, University of Florida, Gainesville, Florida, USA., Chang YD; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Rajasekhara S; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Smith JE; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Soares HP; Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Clare-Salzler M; Department of Pathology, Immunology & Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA., Starostik P; Department of Pathology, Immunology & Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA., George TJ; Division of Hematology and Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA., McLeod HL; Intermountain Health, St George, Utah, USA., Fillingim RB; Department of Community Dentistry and Behavioral Science, College of Dentistry, Gainesville, Florida, USA.; Clinical and Translational Science Institute, University of Florida, Gainesville, Florida, USA., Hicks JK; Department of Individualized Cancer Management, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Cavallari LH; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.
Source: Pharmacotherapy [Pharmacotherapy] 2023 Dec; Vol. 43 (12), pp. 1286-1296. Date of Electronic Publication: 2023 Sep 21.
Publication Type: Randomized Controlled Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8111305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9114 (Electronic) Linking ISSN: 02770008 NLM ISO Abbreviation: Pharmacotherapy Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CYP2D6-guided opioid therapy for adults with cancer pain: A randomized implementation clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Mosley+SA%22">Mosley SA</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.; Department of Clinical Pharmacy, University of Southern California, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Cicali+E%22">Cicali E</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Del+Cueto+A%22">Del Cueto A</searchLink>; Department of Individualized Cancer Management, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Portman+DG%22">Portman DG</searchLink>; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Donovan+KA%22">Donovan KA</searchLink>; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Gong+Y%22">Gong Y</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Langaee+T%22">Langaee T</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Gopalan+P%22">Gopalan P</searchLink>; Division of Hematology and Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Schmit+J%22">Schmit J</searchLink>; Division of Hematology and Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Starr+JS%22">Starr JS</searchLink>; Division of Hematology/Oncology, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Silver+N%22">Silver N</searchLink>; Department of Otolaryngology, College of Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Chang+YD%22">Chang YD</searchLink>; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Rajasekhara+S%22">Rajasekhara S</searchLink>; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Smith+JE%22">Smith JE</searchLink>; Department of Supportive Care Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Soares+HP%22">Soares HP</searchLink>; Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Clare-Salzler+M%22">Clare-Salzler M</searchLink>; Department of Pathology, Immunology & Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Starostik+P%22">Starostik P</searchLink>; Department of Pathology, Immunology & Laboratory Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22George+TJ%22">George TJ</searchLink>; Division of Hematology and Oncology, Department of Medicine, College of Medicine, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22McLeod+HL%22">McLeod HL</searchLink>; Intermountain Health, St George, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Fillingim+RB%22">Fillingim RB</searchLink>; Department of Community Dentistry and Behavioral Science, College of Dentistry, Gainesville, Florida, USA.; Clinical and Translational Science Institute, University of Florida, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Hicks+JK%22">Hicks JK</searchLink>; Department of Individualized Cancer Management, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Cavallari+LH%22">Cavallari LH</searchLink>; Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.
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