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Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19.

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Title: Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19.
Authors: Geyer CE; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Chen HJ; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Bye AP; Institute for Cardiovascular and Metabolic Research, and School of Biological Sciences, University of Reading, Reading, UK.; Molecular and Clinical Sciences Research Institute, St George's University, London, UK.; School of Pharmacy, University of Reading, Reading, UK., Manz XD; Pulmonary Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands., Guerra D; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Caniels TG; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Bijl TP; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Griffith GR; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam Institute for Infection and Immunity, Inflammatory Diseases, Amsterdam University Medical Centers, Amsterdam, Netherlands., Hoepel W; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., de Taeye SW; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Veth J; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Vlaar AP; Department of Intensive Care Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., Vidarsson G; Experimental Immunohematology, Sanquin Research, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands., Bogaard HJ; Pulmonary Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands., Aman J; Pulmonary Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands., Gibbins JM; Institute for Cardiovascular and Metabolic Research, and School of Biological Sciences, University of Reading, Reading, UK., van Gils MJ; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands., de Winther MP; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam Institute for Infection and Immunity, Inflammatory Diseases, Amsterdam University Medical Centers, Amsterdam, Netherlands m.dewinther@amsterdamumc.nl., den Dunnen J; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands j.dendunnen@amsterdamumc.nl.
Corporate Authors: Amsterdam UMC COVID-19 Biobank
Source: Life science alliance [Life Sci Alliance] 2023 Sep 12; Vol. 6 (11). Date of Electronic Publication: 2023 Sep 12 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Geyer+CE%22">Geyer CE</searchLink>; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Chen+HJ%22">Chen HJ</searchLink>; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bye+AP%22">Bye AP</searchLink>; Institute for Cardiovascular and Metabolic Research, and School of Biological Sciences, University of Reading, Reading, UK.; Molecular and Clinical Sciences Research Institute, St George's University, London, UK.; School of Pharmacy, University of Reading, Reading, UK.<br /><searchLink fieldCode="AU" term="%22Manz+XD%22">Manz XD</searchLink>; Pulmonary Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Guerra+D%22">Guerra D</searchLink>; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Caniels+TG%22">Caniels TG</searchLink>; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bijl+TP%22">Bijl TP</searchLink>; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Griffith+GR%22">Griffith GR</searchLink>; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam Institute for Infection and Immunity, Inflammatory Diseases, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Hoepel+W%22">Hoepel W</searchLink>; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Taeye+SW%22">de Taeye SW</searchLink>; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Veth+J%22">Veth J</searchLink>; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Vlaar+AP%22">Vlaar AP</searchLink>; Department of Intensive Care Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Vidarsson+G%22">Vidarsson G</searchLink>; Experimental Immunohematology, Sanquin Research, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Bogaard+HJ%22">Bogaard HJ</searchLink>; Pulmonary Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Aman+J%22">Aman J</searchLink>; Pulmonary Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Gibbins+JM%22">Gibbins JM</searchLink>; Institute for Cardiovascular and Metabolic Research, and School of Biological Sciences, University of Reading, Reading, UK.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; Medical Microbiology and Infection Prevention, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Winther+MP%22">de Winther MP</searchLink>; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam Institute for Infection and Immunity, Inflammatory Diseases, Amsterdam University Medical Centers, Amsterdam, Netherlands m.dewinther@amsterdamumc.nl.<br /><searchLink fieldCode="AU" term="%22den+Dunnen+J%22">den Dunnen J</searchLink>; Center for Experimental and Molecular Medicine, Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands j.dendunnen@amsterdamumc.nl.
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  Data: <searchLink fieldCode="CA" term="%22Amsterdam+UMC+COVID-19+Biobank%22">Amsterdam UMC COVID-19 Biobank</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101728869%22">Life science alliance</searchLink> [Life Sci Alliance] 2023 Sep 12; Vol. 6 (11). <i>Date of Electronic Publication: </i>2023 Sep 12 (<i>Print Publication: </i>2023).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Life+Science+Alliance%2C+LLC%22">Life Science Alliance, LLC </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101728869 <i>Publication Model: </i>Electronic-Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2575-1077 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225751077%22">25751077 </searchLink><i>NLM ISO Abbreviation: </i>Life Sci Alliance <i>Subsets: </i>MEDLINE
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