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Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.

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Title: Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.
Authors: Albert-Gasco H; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK., Smith HL; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK., Alvarez-Castelao B; Department of Biochemistry and Molecular Biology, Veterinary School, Complutense University of Madrid, 28040 Madrid, Spain.; The San Carlos Hospital Health Research Institute, IdISSC, 28040 Madrid, Spain., Swinden D; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK., Halliday M; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK., Janaki-Raman S; Altos Labs Inc, Redwood City, CA 94065, USA., Butcher AJ; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK., Mallucci GR; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK.
Source: Brain : a journal of neurology [Brain] 2024 Feb 01; Vol. 147 (2), pp. 649-664.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration.
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  Data: <searchLink fieldCode="AU" term="%22Albert-Gasco+H%22">Albert-Gasco H</searchLink>; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK.<br /><searchLink fieldCode="AU" term="%22Smith+HL%22">Smith HL</searchLink>; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK.<br /><searchLink fieldCode="AU" term="%22Alvarez-Castelao+B%22">Alvarez-Castelao B</searchLink>; Department of Biochemistry and Molecular Biology, Veterinary School, Complutense University of Madrid, 28040 Madrid, Spain.; The San Carlos Hospital Health Research Institute, IdISSC, 28040 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Swinden+D%22">Swinden D</searchLink>; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK.<br /><searchLink fieldCode="AU" term="%22Halliday+M%22">Halliday M</searchLink>; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK.<br /><searchLink fieldCode="AU" term="%22Janaki-Raman+S%22">Janaki-Raman S</searchLink>; Altos Labs Inc, Redwood City, CA 94065, USA.<br /><searchLink fieldCode="AU" term="%22Butcher+AJ%22">Butcher AJ</searchLink>; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK.<br /><searchLink fieldCode="AU" term="%22Mallucci+GR%22">Mallucci GR</searchLink>; UK Dementia Research Institute and Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0AH, UK.; Cambridge Institute of Science, Altos Labs, Great Abington CB21 6GP, UK.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372537 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2156 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200068950%22">00068950 </searchLink><i>NLM ISO Abbreviation: </i>Brain <i>Subsets: </i>MEDLINE
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        Value: 10.1093/brain/awad313
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              Text: 2024 Feb 01
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