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Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila.

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Title: Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila.
Authors: Pandey A; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA. Ashutosh.Pandey@bcm.edu., Galeone A; Department of Biosciences, University of Milan, Milan, Italy.; Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy., Han SY; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA., Story BA; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Consonni G; Department of Biosciences, University of Milan, Milan, Italy., Mueller WF; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany., Steinmetz LM; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Genetics, School of Medicine, Stanford University, Stanford, USA., Vaccari T; Department of Biosciences, University of Milan, Milan, Italy., Jafar-Nejad H; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA. hamedj@bcm.edu.; Genetics & Genomic Graduate Program, Baylor College of Medicine, Houston, USA. hamedj@bcm.edu.; Development, Disease Models & Therapeutics Graduate Program, Baylor College of Medicine, Houston, USA. hamedj@bcm.edu.
Source: Nature communications [Nat Commun] 2023 Sep 13; Vol. 14 (1), pp. 5667. Date of Electronic Publication: 2023 Sep 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila.
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  Data: <searchLink fieldCode="AU" term="%22Pandey+A%22">Pandey A</searchLink>; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA. Ashutosh.Pandey@bcm.edu.<br /><searchLink fieldCode="AU" term="%22Galeone+A%22">Galeone A</searchLink>; Department of Biosciences, University of Milan, Milan, Italy.; Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Han+SY%22">Han SY</searchLink>; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA.<br /><searchLink fieldCode="AU" term="%22Story+BA%22">Story BA</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Consonni+G%22">Consonni G</searchLink>; Department of Biosciences, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mueller+WF%22">Mueller WF</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Steinmetz+LM%22">Steinmetz LM</searchLink>; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.; Department of Genetics, School of Medicine, Stanford University, Stanford, USA.<br /><searchLink fieldCode="AU" term="%22Vaccari+T%22">Vaccari T</searchLink>; Department of Biosciences, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Jafar-Nejad+H%22">Jafar-Nejad H</searchLink>; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, USA. hamedj@bcm.edu.; Genetics & Genomic Graduate Program, Baylor College of Medicine, Houston, USA. hamedj@bcm.edu.; Development, Disease Models & Therapeutics Graduate Program, Baylor College of Medicine, Houston, USA. hamedj@bcm.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Sep 13; Vol. 14 (1), pp. 5667. <i>Date of Electronic Publication: </i>2023 Sep 13.
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