P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.

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Title: P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
Authors: Beltran-Lobo P; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK., Hughes MM; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK., Troakes C; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; London Neurodegenerative Diseases Brain Bank, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK., Croft CL; UK Dementia Research Institute, UCL Institute of Neurology, University College London, London, UK; The Francis Crick Institute, London, UK., Rupawala H; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK., Jutzi D; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; UK Dementia Research Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Ruepp MD; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; UK Dementia Research Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Jimenez-Sanchez M; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK., Perkinton MS; Neuroscience, IMED Biotechnology Unit, AstraZeneca, Cambridge CB21 6GH, UK., Kassiou M; School of Chemistry, Faculty of Science, University of Sydney, Sydney, New South Wales, Australia., Golde TE; Department of Pharmacology and Chemical Biology, Department of Neurology, Emory Center for Neurodegenerative Disease, Emory University, Atlanta, GA, USA., Hanger DP; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK., Verkhratsky A; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK; Achucarro Center for Neuroscience, IKERBASQUE, 48011 Bilbao, Spain; Department of Forensic Analytical Toxicology, School of Forensic Medicine, China Medical University, Shenyang, China; Department of Stem Cell Biology, State Research Institute Centre for Innovative Medicine, LT-01102 Vilnius, Lithuania., Perez-Nievas BG; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK. Electronic address: Beatriz.gomez_perez-nievas@kcl.ac.uk., Noble W; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; University of Exeter, Department of Clinical and Biomedical Science, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK. Electronic address: w.noble2@exeter.ac.uk.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2023 Nov; Vol. 114, pp. 414-429. Date of Electronic Publication: 2023 Sep 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: P2X<subscript>7</subscript>R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
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  Data: <searchLink fieldCode="AU" term="%22Beltran-Lobo+P%22">Beltran-Lobo P</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK.<br /><searchLink fieldCode="AU" term="%22Hughes+MM%22">Hughes MM</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK.<br /><searchLink fieldCode="AU" term="%22Troakes+C%22">Troakes C</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; London Neurodegenerative Diseases Brain Bank, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Croft+CL%22">Croft CL</searchLink>; UK Dementia Research Institute, UCL Institute of Neurology, University College London, London, UK; The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Rupawala+H%22">Rupawala H</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK.<br /><searchLink fieldCode="AU" term="%22Jutzi+D%22">Jutzi D</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; UK Dementia Research Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ruepp+MD%22">Ruepp MD</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; UK Dementia Research Institute, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Jimenez-Sanchez+M%22">Jimenez-Sanchez M</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK.<br /><searchLink fieldCode="AU" term="%22Perkinton+MS%22">Perkinton MS</searchLink>; Neuroscience, IMED Biotechnology Unit, AstraZeneca, Cambridge CB21 6GH, UK.<br /><searchLink fieldCode="AU" term="%22Kassiou+M%22">Kassiou M</searchLink>; School of Chemistry, Faculty of Science, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Golde+TE%22">Golde TE</searchLink>; Department of Pharmacology and Chemical Biology, Department of Neurology, Emory Center for Neurodegenerative Disease, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Hanger+DP%22">Hanger DP</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK.<br /><searchLink fieldCode="AU" term="%22Verkhratsky+A%22">Verkhratsky A</searchLink>; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK; Achucarro Center for Neuroscience, IKERBASQUE, 48011 Bilbao, Spain; Department of Forensic Analytical Toxicology, School of Forensic Medicine, China Medical University, Shenyang, China; Department of Stem Cell Biology, State Research Institute Centre for Innovative Medicine, LT-01102 Vilnius, Lithuania.<br /><searchLink fieldCode="AU" term="%22Perez-Nievas+BG%22">Perez-Nievas BG</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK. Electronic address: Beatriz.gomez_perez-nievas@kcl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Noble+W%22">Noble W</searchLink>; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Basic and Clinical Neuroscience, 5 Cutcombe Road, London SE5 9RX, UK; University of Exeter, Department of Clinical and Biomedical Science, Hatherly Laboratories, Prince of Wales Road, Exeter EX4 4PS, UK. Electronic address: w.noble2@exeter.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%228800478%22">Brain, behavior, and immunity</searchLink> [Brain Behav Immun] 2023 Nov; Vol. 114, pp. 414-429. <i>Date of Electronic Publication: </i>2023 Sep 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8800478 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2139 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208891591%22">08891591 </searchLink><i>NLM ISO Abbreviation: </i>Brain Behav Immun <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bbi.2023.09.011
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      – Code: eng
        Text: English
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        StartPage: 414
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      – TitleFull: P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes.
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              Text: 2023 Nov
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