Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.

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Title: Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.
Authors: Zhang S; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA., Zhang H; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA., Forrest MP; Department of Neuroscience, Northwestern University, Chicago, IL 60611, USA.; Center for Autism and Neurodevelopment, Northwestern University, Chicago, IL 60611, USA., Zhou Y; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA., Sun X; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA., Bagchi VA; Department of Neuroscience, Northwestern University, Chicago, IL 60611, USA.; Center for Autism and Neurodevelopment, Northwestern University, Chicago, IL 60611, USA., Kozlova A; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA., Santos MD; Department of Neuroscience, Northwestern University, Chicago, IL 60611, USA.; Center for Autism and Neurodevelopment, Northwestern University, Chicago, IL 60611, USA., Piguel NH; Department of Neuroscience, Northwestern University, Chicago, IL 60611, USA.; Center for Autism and Neurodevelopment, Northwestern University, Chicago, IL 60611, USA., Dionisio LE; Department of Neuroscience, Northwestern University, Chicago, IL 60611, USA.; Center for Autism and Neurodevelopment, Northwestern University, Chicago, IL 60611, USA., Sanders AR; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA., Pang ZP; Department of Neuroscience and Cell Biology, Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA., He X; Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA., Penzes P; Department of Neuroscience, Northwestern University, Chicago, IL 60611, USA.; Center for Autism and Neurodevelopment, Northwestern University, Chicago, IL 60611, USA.; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Duan J; Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA.
Source: Cell genomics [Cell Genom] 2023 Aug 28; Vol. 3 (9), pp. 100399. Date of Electronic Publication: 2023 Aug 28 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2666-979X
DOI:10.1016/j.xgen.2023.100399