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Tyrosine-Mutant AAV8 Vector Mediated Efficient and Safe Gene Transfer of Pigment Epithelium-Derived Factor to Mouse Lungs.

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Title: Tyrosine-Mutant AAV8 Vector Mediated Efficient and Safe Gene Transfer of Pigment Epithelium-Derived Factor to Mouse Lungs.
Authors: Ferreira DP; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil., Martini SV; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Oliveira HA; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil., Silva AL; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil., Shenoy S; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chen D; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Simon V; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Han E; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., West NE; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Suk JS; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA., Rocco PRM; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil., Petrs-Silva H; Laboratory of Gene Therapy and Viral Vectors, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Morales MM; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil., Cruz FF; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil, ffcruz@biof.ufrj.br.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.
Source: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology [Cell Physiol Biochem] 2023 Sep 18; Vol. 57 (5), pp. 331-344.
Publication Type: Journal Article
Journal Info: Publisher: Cell Physiol Biochem Press GmbH & Co KG Country of Publication: Germany NLM ID: 9113221 Publication Model: Print Cited Medium: Internet ISSN: 1421-9778 (Electronic) Linking ISSN: 10158987 NLM ISO Abbreviation: Cell Physiol Biochem Subsets: MEDLINE
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  Data: Tyrosine-Mutant AAV8 Vector Mediated Efficient and Safe Gene Transfer of Pigment Epithelium-Derived Factor to Mouse Lungs.
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  Data: <searchLink fieldCode="AU" term="%22Ferreira+DP%22">Ferreira DP</searchLink>; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Martini+SV%22">Martini SV</searchLink>; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+HA%22">Oliveira HA</searchLink>; Laboratory of Immunopharmacology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+AL%22">Silva AL</searchLink>; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Shenoy+S%22">Shenoy S</searchLink>; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Simon+V%22">Simon V</searchLink>; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Han+E%22">Han E</searchLink>; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22West+NE%22">West NE</searchLink>; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Suk+JS%22">Suk JS</searchLink>; Center for Nanomedicine, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rocco+PRM%22">Rocco PRM</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Petrs-Silva+H%22">Petrs-Silva H</searchLink>; Laboratory of Gene Therapy and Viral Vectors, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Morales+MM%22">Morales MM</searchLink>; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Cruz+FF%22">Cruz FF</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil, ffcruz@biof.ufrj.br.; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.
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