Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility.
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| Title: | Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility. |
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| Authors: | Schmidheini L; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.; Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Mathis N; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Marquart KF; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.; Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Rothgangl T; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Kissling L; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Böck D; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Chanez C; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Wang JP; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Jinek M; Department of Biochemistry, University of Zurich, Zurich, Switzerland., Schwank G; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. schwank@pharma.uzh.ch. |
| Source: | Nature chemical biology [Nat Chem Biol] 2024 Mar; Vol. 20 (3), pp. 333-343. Date of Electronic Publication: 2023 Sep 21. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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