Utility of Coproporphyrin-I Determination in First-in-Human Study for Early Evaluation of OATP1B Inhibitory Potential Based on Investigation of Ensitrelvir, an Oral SARS-CoV-2 3C-Like Protease Inhibitor.
Saved in:
| Title: | Utility of Coproporphyrin-I Determination in First-in-Human Study for Early Evaluation of OATP1B Inhibitory Potential Based on Investigation of Ensitrelvir, an Oral SARS-CoV-2 3C-Like Protease Inhibitor. |
|---|---|
| Authors: | Watari R; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan. Electronic address: ryosuke.watari@shionogi.co.jp., Sawada H; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan., Hashimoto H; Department of ADMET and Analytical Chemistry II, Shionogi TechnoAdvance Research & Co., Ltd, Japan., Kasai Y; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan., Oka R; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan., Shimizu R; Clinical Pharmacology & Pharmacokinetics, Shionogi & Co., Ltd, Japan., Matsuzaki T; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan. |
| Source: | Journal of pharmaceutical sciences [J Pharm Sci] 2024 Mar; Vol. 113 (3), pp. 798-805. Date of Electronic Publication: 2023 Sep 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1520-6017 |
|---|---|
| DOI: | 10.1016/j.xphs.2023.09.016 |
