4-Phenylbutyrate promoted wild-type γ-aminobutyric acid type A receptor trafficking, reduced endoplasmic reticulum stress, and mitigated seizures in Gabrg2+/Q390X mice associated with Dravet syndrome.
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| Title: | 4-Phenylbutyrate promoted wild-type γ-aminobutyric acid type A receptor trafficking, reduced endoplasmic reticulum stress, and mitigated seizures in Gabrg2+/Q390X mice associated with Dravet syndrome. |
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| Authors: | Shen W; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Flamm C; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Delahanty AJ; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Casteel E; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Biven M; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., DeLeeuw MB; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, Nashville, Tennessee, USA., Poliquin S; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Nwosu G; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Randhave K; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kang JQ; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Biochemistry, Cancer Biology, Neuroscience and Pharmacology, Meharry Medical College, Nashville, Tennessee, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA. |
| Source: | Epilepsia [Epilepsia] 2024 Jan; Vol. 65 (1), pp. 204-217. Date of Electronic Publication: 2023 Nov 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1528-1167 |
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| DOI: | 10.1111/epi.17779 |
