A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation.
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| Title: | A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation. |
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| Authors: | Garnish SE; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Martin KR; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Kauppi M; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Jackson VE; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Ambrose R; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia., Eng VV; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Microbiology, Monash University, Clayton, VIC, Australia., Chiou S; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Meng Y; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Frank D; The Walter and Eliza Hall Institute, Parkville, VIC, Australia., Tovey Crutchfield EC; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, Parkville, VIC, Australia., Patel KM; The Walter and Eliza Hall Institute, Parkville, VIC, Australia., Jacobsen AV; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Atkin-Smith GK; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Di Rago L; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Doerflinger M; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Horne CR; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Hall C; The Walter and Eliza Hall Institute, Parkville, VIC, Australia., Young SN; The Walter and Eliza Hall Institute, Parkville, VIC, Australia., Cook M; Centre for Personalised Immunology and Canberra Clinical Genomics, Australian National University, Canberra, ACT, Australia.; Cambridge Institute for Therapeutic Immunology and Infectious Disease, University of Cambridge, Cambridge, UK., Athanasopoulos V; Department of Immunology and Infection, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia., Vinuesa CG; Centre for Personalised Immunology and Canberra Clinical Genomics, Australian National University, Canberra, ACT, Australia.; Department of Immunology and Infection, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia.; The Francis Crick Institute, London, UK.; University College London, London, UK.; China Australia Centre for Personalized Immunology (CACPI), Renji Hospital, Shanghai Jiao Tong University School of Medicine (SJTUSM), Shanghai, China., Lawlor KE; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia., Wicks IP; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Ebert G; Institute of Virology, Technical University of Munich/Helmholtz Munich, Munich, Germany., Ng AP; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia.; Clinical Haematology Department, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Parkville, VIC, Australia., Slade CA; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia.; Department of Clinical Immunology & Allergy, Royal Melbourne Hospital, Parkville, VIC, Australia., Pearson JS; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia.; Department of Microbiology, Monash University, Clayton, VIC, Australia., Samson AL; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Silke J; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Murphy JM; The Walter and Eliza Hall Institute, Parkville, VIC, Australia.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia., Hildebrand JM; The Walter and Eliza Hall Institute, Parkville, VIC, Australia. jhildebrand@wehi.edu.au.; University of Melbourne, Department of Medical Biology, Parkville, VIC, Australia. jhildebrand@wehi.edu.au. |
| Source: | Nature communications [Nat Commun] 2023 Sep 28; Vol. 14 (1), pp. 6046. Date of Electronic Publication: 2023 Sep 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-023-41724-6 |
