Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension.

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Title: Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension.
Authors: Simpson CE; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States., Ambade AS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States., Harlan R; Johns Hopkins All Children's Molecular Determinants Core, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, United States., Roux A; Johns Hopkins All Children's Molecular Determinants Core, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, United States., Aja S; Johns Hopkins All Children's Molecular Determinants Core, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, United States., Graham D; Johns Hopkins All Children's Molecular Determinants Core, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, United States., Shah AA; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States., Hummers LK; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States., Hemnes AR; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States., Leopold JA; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States., Horn EM; Division of Cardiology, Department of Medicine, Cornell University Medical Center, New York, New York, United States., Berman-Rosenzweig ES; Division of Pediatric Cardiology, Columbia University Medical Center/NewYork-Presbyterian Hospital, New York, New York, United States., Grunig G; Divisions of Environmental and Pulmonary Medicine, Department of Medicine, NYU Grossman School of Medicine, New York, New York, United States., Aldred MA; Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States., Barnard J; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States., Comhair SAA; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States., Tang WHW; Division of Heart Failure and Transplant Medicine, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, United States., Griffiths M; Division of Pediatric Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States., Rischard F; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Arizona College of Medicine, Tucson, Arizona, United States., Frantz RP; Division of Circulatory Failure, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States., Erzurum SC; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States., Beck GJ; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States., Hill NS; Pulmonary, Critical Care and Sleep Division, Tufts University, Boston, Massachusetts, United States., Mathai SC; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States., Hassoun PM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States., Damico RL; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States.
Corporate Authors: the PVDOMICS Study Group
Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Nov 01; Vol. 325 (5), pp. L617-L627. Date of Electronic Publication: 2023 Oct 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1504 (Electronic) Linking ISSN: 10400605 NLM ISO Abbreviation: Am J Physiol Lung Cell Mol Physiol Subsets: MEDLINE
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  Data: Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension.
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Johns Hopkins All Children's Molecular Determinants Core, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, United States.<br /><searchLink fieldCode="AU" term="%22Shah+AA%22">Shah AA</searchLink>; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Hummers+LK%22">Hummers LK</searchLink>; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Hemnes+AR%22">Hemnes AR</searchLink>; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee, United States.<br /><searchLink fieldCode="AU" term="%22Leopold+JA%22">Leopold JA</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Horn+EM%22">Horn EM</searchLink>; Division of Cardiology, Department of Medicine, Cornell University Medical Center, New York, New York, United States.<br /><searchLink fieldCode="AU" term="%22Berman-Rosenzweig+ES%22">Berman-Rosenzweig ES</searchLink>; Division of Pediatric Cardiology, Columbia University Medical Center/NewYork-Presbyterian Hospital, New York, New York, United States.<br /><searchLink fieldCode="AU" term="%22Grunig+G%22">Grunig G</searchLink>; Divisions of Environmental and Pulmonary Medicine, Department of Medicine, NYU Grossman School of Medicine, New York, New York, United States.<br /><searchLink fieldCode="AU" term="%22Aldred+MA%22">Aldred MA</searchLink>; Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States.<br /><searchLink fieldCode="AU" term="%22Barnard+J%22">Barnard J</searchLink>; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Comhair+SAA%22">Comhair SAA</searchLink>; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Tang+WHW%22">Tang WHW</searchLink>; Division of Heart Failure and Transplant Medicine, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Griffiths+M%22">Griffiths M</searchLink>; Division of Pediatric Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States.<br /><searchLink fieldCode="AU" term="%22Rischard+F%22">Rischard F</searchLink>; Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Arizona College of Medicine, Tucson, Arizona, United States.<br /><searchLink fieldCode="AU" term="%22Frantz+RP%22">Frantz RP</searchLink>; Division of Circulatory Failure, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States.<br /><searchLink fieldCode="AU" term="%22Erzurum+SC%22">Erzurum SC</searchLink>; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Beck+GJ%22">Beck GJ</searchLink>; Department of Inflammation and Immunity, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Hill+NS%22">Hill NS</searchLink>; Pulmonary, Critical Care and Sleep Division, Tufts University, Boston, Massachusetts, United States.<br /><searchLink fieldCode="AU" term="%22Mathai+SC%22">Mathai SC</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Hassoun+PM%22">Hassoun PM</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Damico+RL%22">Damico RL</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States.
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  Data: <searchLink fieldCode="JN" term="%22100901229%22">American journal of physiology. Lung cellular and molecular physiology</searchLink> [Am J Physiol Lung Cell Mol Physiol] 2023 Nov 01; Vol. 325 (5), pp. L617-L627. <i>Date of Electronic Publication: </i>2023 Oct 03.
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