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Intracoronary delivery of extracellular vesicles from human cardiac progenitor cells reduces infarct size in porcine acute myocardial infarction.

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Title: Intracoronary delivery of extracellular vesicles from human cardiac progenitor cells reduces infarct size in porcine acute myocardial infarction.
Authors: Emmert MY; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; Institute for Regenerative Medicine (IREM), University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland., Burrello J; Department of Medical Sciences, University of Turin, Via Giuseppe Verdi 8, 10124 Turin, Italy., Wolint P; Division of Surgical Research, University Hospital Zurich, University of Zurich, Sternwartstrasse 14, 8091 Zurich, Switzerland., Hilbe M; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, 8057 Zurich, Switzerland., Andriolo G; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland., Balbi C; Laboratory of Cellular and Molecular Cardiology, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, V ia Tesserete 48, 6900 Lugano, Switzerland.; Center for Molecular Cardiology, University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland., Provasi E; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland., Turchetto L; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland., Radrizzani M; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland., Nazari-Shafti TZ; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany., Cesarovic N; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; Department of Health Sciences and Technology, ETH Zurich, Rämistrasse 101, 8092 Zurich, Switzerland., Neuber S; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany., Falk V; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; Department of Health Sciences and Technology, ETH Zurich, Rämistrasse 101, 8092 Zurich, Switzerland., Hoerstrup SP; Institute for Regenerative Medicine (IREM), University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland., Hemetsberger R; Department of Cardiology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria., Gyöngyösi M; Department of Cardiology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria., Barile L; Laboratory for Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, V ia Tesserete 48, 6900 Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Via Buffi 13, 6900 Lugano, Switzerland., Vassalli G; Laboratory of Cellular and Molecular Cardiology, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, V ia Tesserete 48, 6900 Lugano, Switzerland.; Center for Molecular Cardiology, University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Via Buffi 13, 6900 Lugano, Switzerland.
Source: European heart journal [Eur Heart J] 2024 Mar 01; Vol. 45 (9), pp. 728-732.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intracoronary delivery of extracellular vesicles from human cardiac progenitor cells reduces infarct size in porcine acute myocardial infarction.
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  Data: <searchLink fieldCode="AU" term="%22Emmert+MY%22">Emmert MY</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; Institute for Regenerative Medicine (IREM), University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Burrello+J%22">Burrello J</searchLink>; Department of Medical Sciences, University of Turin, Via Giuseppe Verdi 8, 10124 Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Wolint+P%22">Wolint P</searchLink>; Division of Surgical Research, University Hospital Zurich, University of Zurich, Sternwartstrasse 14, 8091 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hilbe+M%22">Hilbe M</searchLink>; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, 8057 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Andriolo+G%22">Andriolo G</searchLink>; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Balbi+C%22">Balbi C</searchLink>; Laboratory of Cellular and Molecular Cardiology, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, V ia Tesserete 48, 6900 Lugano, Switzerland.; Center for Molecular Cardiology, University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Provasi+E%22">Provasi E</searchLink>; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Turchetto+L%22">Turchetto L</searchLink>; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Radrizzani+M%22">Radrizzani M</searchLink>; Lugano Cell Factory, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Via Tesserete 48, 6900 Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nazari-Shafti+TZ%22">Nazari-Shafti TZ</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Cesarovic+N%22">Cesarovic N</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; Department of Health Sciences and Technology, ETH Zurich, Rämistrasse 101, 8092 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Neuber+S%22">Neuber S</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Falk+V%22">Falk V</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charite (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany.; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.; Department of Health Sciences and Technology, ETH Zurich, Rämistrasse 101, 8092 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hoerstrup+SP%22">Hoerstrup SP</searchLink>; Institute for Regenerative Medicine (IREM), University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hemetsberger+R%22">Hemetsberger R</searchLink>; Department of Cardiology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Gyöngyösi+M%22">Gyöngyösi M</searchLink>; Department of Cardiology, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Barile+L%22">Barile L</searchLink>; Laboratory for Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, V ia Tesserete 48, 6900 Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Via Buffi 13, 6900 Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vassalli+G%22">Vassalli G</searchLink>; Laboratory of Cellular and Molecular Cardiology, Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, V ia Tesserete 48, 6900 Lugano, Switzerland.; Center for Molecular Cardiology, University of Zurich, Wagistrasse 12, 8952 Schlieren, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Via Buffi 13, 6900 Lugano, Switzerland.
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